Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Schmidt, Felix ^a,b   Levin, Johannes ^a   Kamp, Frits ^a,b   Kretzschmar, Hans ^b   Giese, Armin ^b   Bötzel, Kai ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; BAICALEIN; IRON; PORIN;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DEGENERATIVE DISEASE; ELECTROPHYSIOLOGY; HUMAN; INCUBATION TIME; LIPID BILAYER; MEMBRANE CONDUCTANCE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; OLIGOMERIZATION; PROTEIN AGGREGATION; SINGLE CHANNEL ELECTROPHYSIOLOGY; VOLTAGE CLAMP;

ALPHA-SYNUCLEIN; CATIONS; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGICAL PHENOMENA; HUMANS; LIPID BILAYERS; MODELS, BIOLOGICAL; POROSITY; PROTEIN STRUCTURE, QUATERNARY; TIME FACTORS;

BACTERIA (MICROORGANISMS);

EID: 84864538288     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042545     Document Type: Article

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