A phage display vector optimized for the generation of human antibody combinatorial libraries and the molecular cloning of monoclonal antibody fragments

New Microbiologica

Volumn 35, Issue 3, 2012, Pages 289-294

  Solforosi, Laura ^a   Mancini, Nicasio ^a   Canducci, Filippo ^a   Clementi, Nicola ^a   Sautto, Giuseppe Andrea ^a   Diotti, Roberta Antonia ^a   Clementi, Massimo ^a   Burioni, Roberto ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Combinatorial antibody library; Human monoclonal antibody fragments (mFabs); Phage display; Phagemid vector

Indexed keywords

COMPLEMENTARY DNA; CORE PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; NP PROTEIN, INFLUENZA A VIRUS; RECOMBINANT PROTEIN; RNA BINDING PROTEIN; SIGNAL PEPTIDE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; ESCHERICHIA COLI; GENE VECTOR; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; LACTOSE OPERON; MALE; METHODOLOGY; MIDDLE AGED; MOLECULAR CLONING; PEPTIDE LIBRARY; PROMOTER REGION;

ANIMALS; CELL LINE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ESCHERICHIA COLI; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INFLUENZA A VIRUS, H1N1 SUBTYPE; LAC OPERON; MALE; MIDDLE AGED; PEPTIDE LIBRARY; PROMOTER REGIONS, GENETIC; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; RNA-BINDING PROTEINS; VIRAL CORE PROTEINS;

ESCHERICHIA COLI; INFLUENZA A VIRUS;

EID: 84864530741     PISSN: 11217138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. BARBAS C. F. III., SCOTT J. K., SILVERMAN G. J. (2001). Phage display: a laboratory manual. Cold Spring Harbor Laboratory Press, New York.
2. BARBAS C. F. III., KANG A. S., LERNER R. A., BENKOVIC S. J. (1991). Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proceedings of the National Academy of Sciences of the United States of America 88(18), 7978-7982. (Pubitemid 21915278)
3. BARBAS C. F. III., CROWE J. E. JR., CABABA D., JONES T. M., ZEBEDEE S. L., MURPHY B. R., CHANOCK R. M., BURTON D. R. (1992). Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity. Proceedings of the National Academy of Sciences of the United States of America. 89(21), 10164-10168.
4. BENDER E., WOOF J. M., ATKIN J. D., BARKER M. D., BEBBINGTON C. R., BURTON D. R. (1993). Recombinant human antibodies: linkage of an Fab fragment from a combinatorial library to an Fc fragment for expression in mammalian cell culture. Human antibodies and hybridomas. 4(2), 74-79. (Pubitemid 23167098)
5. BREITLING F., DUBEL S., SEEHAUS T., KLEWINGHAUS I., LITTLE M. (1991). A surface expression vector for antibody screening. Gene. 104(2), 147-153.
6. BUGLI F., BASTIDAS R., BURTON D. R., WILLIAMSON R. A., CLEMENTI M., BURIONI R. (2001). Molecular profile of a human monoclonal antibody Fab fragment specific for Epstein-Barr virus gp350/220 antigen. Human Immunology. 62(4), 362-367. (Pubitemid 32298978)
7. BUGLI F., PARONI STERBINI F., GRAFFEO R., CARIDI F., IANTOMASI R., TORELLI R., MASUCCI L., CATTANI P., FADDA G. (2011). Effective use of nitrocellulose-blotted antigens for phage display monoclonal antibody selection. New Microbiologica. 34(3), 281-286.
8. BURIONI R., WILLIAMSON R. A., SANNA P. P., BLOOM F. E., BURTON D. R. (1994). Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro. Proceedings of the National Academy of Sciences of the United States of America. 91(1), 355-359. (Pubitemid 24018703)
9. BURIONI R., PLAISANT P., RICCIO M. L., ROSSOLINI G. M., SATTA G. (1995). A new plasmid cloning vector for direct detection of recombinant clones, based on inactivation of a bacterial acid phosphatase-en-coding gene. New Microbiologica. 18(2), 201-206.
10. BURIONI R., PLAISANT P., DELLI CARRI V., VANNINI A., SPANU T., CLEMENTI M., FADDA G., VARALDO P. E. (1997). An improved phage display vector for antibody repertoire cloning by construction of combinatorial libraries. Research in virology. 148(2), 161-164. (Pubitemid 27162811)
11. BURIONI R., PLAISANT P., MANZIN A., ROSA D., DELLI CARRI V., BUGLI F., SOLFOROSI L., ABRIGNANI S., VARALDO P. E., FADDA G., CLEMENTI M. (1998). Dissection of human humoral immune response against hepatitis C virus E2 glycoprotein by repertoire cloning and generation of recombinant Fab fragments. Hepatology. 28(3), 810-814. (Pubitemid 28405434)
12. BURIONI R., PLAISANT P., BUGLI F., DELLI CARRI V., CLEMENTI M., FADDA G. (1998). A vector for the expression of recombinant monoclonal Fab fragments in bacteria. Journal of Immunological Methods. 217(1-2), 195-199. (Pubitemid 28449043)
13. BURIONI R., MATSUURA Y., MANCINI N., TANI H., MIYAMURA T., VARALDO P. E., CLEMENTI M. (2002). Diverging effects of human recombinant anti-hepatitis C virus (HCV) antibody fragments derived from a single patient on the infectivity of a vesicular stomatitis virus/HCV pseudotype. Journal of Virology. 76(22), 11775-11779. (Pubitemid 35231335)
14. BURIONI R., MANCINI N., CARLETTI S., PEROTTI M., GRIECO A., CANDUCCI F., VARALDO P. E., CLEMENTI M. (2004). Cross-reactive pseudovirus-neutralizing anti-envelope antibodies coexist with antibodies devoid of such activity in persistent hepatitis C virus infection. Virology. 327(2), 242-248. (Pubitemid 39213982)
15. BURIONI R., PEROTTI M., MANCINI N., CLEMENTI M. (2008). Perspectives for the utilization of neutralizing human monoclonal antibodies as anti-HCV drugs. Journal of Hepatology. 49(2), 299-300.
16. BURIONI R., CANDUCCI F., SAITA D., PEROTTI M., MANCINI N., DE MARCO D., CLEMENTI N., CHIEFFO A., DENARO M., CIANFLONE D., MANFREDI A. A., COLOMBO A., MASERI A., CLEMENTI M. (2009). Antigen-driven evolution of B lymphocytes in coronary atherosclerotic plaques. Journal of Immunology. 183(4), 2537-2544.
17. BURIONI R., CANDUCCI F., MANCINI N., CLEMENTI N., SASSI M., DE MARCO D., DIOTTI R. A., SAITA D., SAMPAOLO M., SAUTTO G., PIANEZZE M., CLEMENTI M. (2010). Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV). Virology. 399(1), 144-152.
18. CHANDRA P. K., HAZARI S., POAT B., GUNDUZ F., PRABHU R., LIU G., BURIONI R., CLEMENTI M., GARRY R. F., DASH S. (2010). Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone. Virology Journal. 7, 118.
19. CLEMENTI N., DE MARCO D., MANCINI N., SOLFOROSI L., MORENO G. J., GUBAREVA L. V., MISHIN V., DI PIETRO A., VICENZI E., SICCARDI A. G., CLEMENTI M., BURIONI R. (2011). A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes. PLoS One. 6(12), e28001.
20. CLEMENTI N., MANCINI N., SOLFOROSI L., CASTELLI M., CLEMENTI M., BURIONI R. (2012). Phage display-based strategies for cloning and optimization of monoclonal antibodies directed against human pathogens. International Journal of Molecular Sciences. 13, 8273-8292.
21. CONRAD U., SCHELLER J. (2005). Considerations on an-tibody-phage display methodology. Combinatorial Chemistry & High Throughput Screening. 8(2), 117-126.
22. DE MARCO D., CLEMENTI N., MANCINI N., SOLFOROSI L., MORENO G. J., SUN X., TUMPEY T. M., GUBAREVA L. V., MISHIN V., CLEMENTI M., BURIONI R. (2012). A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses. PLoS One. 7(4), e34415.
23. DESOGUS A., BURIONI R., INGIANNI A., BUGLI F., POMPEI R., FADDA G. (2003). Production and characterization of a human recombinant monoclonal Fab fragment specific for influenza A viruses. Clinical and Diagnostic Laboratory Immunology. 10(4), 680-685. (Pubitemid 36890456)
24. HUSE W. D., SASTRY L., IVERSON S. A., KANG A. S., ALTING-MEES M., BURTON D. R., BENKOVIC S. J., LERNER R. A. (1989). Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science. 246(4935), 1275-1281. (Pubitemid 20066710)
25. KANG A. S., JONES T. M., BURTON D. R. (1991). Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries. Proceedings of the National Academy of Sciences of the United States of America. 88(24), 11120-11123. (Pubitemid 21915991)
26. KIM S. J., JANG M. H., STAPLETON J. T., YOON S. O., KIM K. S., JEON E. S., HONG H. J. (2004). Neutralizing human monoclonal antibodies to hepatitis A virus recovered by phage display. Virology. 318(2), 598-607. (Pubitemid 38224302)
27. LANG I. M., CHUANG T. L., BARBAS C. F. 3RD., SCHLEEF R. R. (1996). Purification of storage granule protein-23. A novel protein identified by phage display technology and interaction with type I plasminogen activator inhibitor. The Journal of Biological Chemistry. 271 (47) 30126-30135. (Pubitemid 26389654)
28. MANCINI N., DIOTTI R. A., PEROTTI M., SAUTTO G., CLEMENTI N., NITTI G., PATEL A. H., BALL J. K., CLEMENTI M., BURIONI R. (2009). Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes. PLoS One. 4(12), e8254.
29. MANCINI N., SOLFOROSI L., CLEMENTI N., DE MARCO D., CLEMENTI M., BURIONI R. (2011). A potential role for monoclonal antibodies in prophylactic and therapeutic treatment of influenza. Antiviral Research. 92(1), 15-26.
30. PEROTTI M., GHIDOLI N., ALTARA R., DIOTTI R. A., CLEMENTI N., DE MARCO D., SASSI M., CLEMENTI M., BURIONI R., MANCINI N. (2008). Hepatitis C virus (HCV)-driven stimulation of subfamily-restricted natural IgM antibodies in mixed cryoglobulinemia. Autoimmunity Reviews. 7(6), 468-472.
31. PLAISANT P., BURIONI R., MANZIN A., SOLFOROSI L., CANDELA M., GABRIELLI A., FADDA G., CLEMENTI M. (1997). Human monoclonal recombinant Fabs specific for HCV antigens obtained by repertoire cloning in phage display combinatorial vectors. Research in Virology. 148(2), 165-169. (Pubitemid 27162812)
32. PORTELA A., DIGARD P. (2002). The influenza virus nu-cleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. The Journal of General Virology. 83(Pt 4), 723-734. (Pubitemid 34284855)
33. QI H., LU H., QIU H. J., PETRENKO V., LIU A. (2012). Phagemid vectors for phage display: properties, characteristics and construction. Journal of Molecular Biology. 417(3), 129-143.
34. RADER C., BARBAS C. F. III. (1997). Phage display of combinatorial antibody libraries. Current Opinion in Biotechnology. 8(4), 503-508. (Pubitemid 27351290)
35. SHU L. L., BEAN W. J., WEBSTER R. G. (1993). Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990. Journal of Virology. 67(5), 2723-2729. (Pubitemid 23118870)
36. WILLIAMSON R. A., BURIONI R., SANNA P. P., PARTRIDGE L. J., BARBAS C. F. III., BURTON D. R. (1993). Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries. Proceedings of the National Academy of Sciences of the United States of America. 90(9), 4141-4145. (Pubitemid 23134182)
37. WILLIAMSON R. A., LAZZAROTTO T., SANNA P. P., BASTIDAS R. B., DALLA CASA B., CAMPISI G., BURIONI R., LANDINI M. P., BURTON D. R. (1997). Use of recombinant human antibody fragments for detection of cy-tomegalovirus antigenemia. J of Clinical Microbiology. 35(8), 2047-2050. (Pubitemid 27318702)
38. YU R., WANG S., YU Y. Z., DU W. S., YANG F., YU W. Y., SUN Z. W. (2009). Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library. Journal of Biomolecular Screening. 14(8), 991-998.
39. ZEBEDEE S. L., BARBAS C. F. III., HOM Y. L., CAOTHIEN R. H., GRAFF R., DEGRAW J., PYATI J., LAPOLLA R., BURTON D. R., LERNER R. A., ET AL. (1992). Human combinatorial antibody libraries to hepatitis B surface antigen. Proceedings of the National Academy of Sciences of the United States of America. 89(8), 3175-3179.