Progress in high-throughput assays of MGMT and APE1 activities in cell extracts

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 736, Issue 1-2, 2012, Pages 25-32

  Georgiadis, Panagiotis ^a   Polychronaki, Nektaria ^a   Kyrtopoulos, Soterios A ^a  

^a INSTITUTE OF BIOLOGY   (Greece)

Author keywords

APE1; BER pathway; MGMT; Molecular epidemiology; O 6 methylguanine; Phenotypic assay

Indexed keywords

6 O BENZYLGUANINE; ALKALINE PHOSPHATASE; APURINIC APYRIMIDINIC ENDONUCLEASE 1; BIOTIN; CYSTEINE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; OLIGONUCLEOTIDE; STREPTAVIDIN; TETRAHYDROFURAN; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SUBSTITUTION; ARTICLE; CELL ASSAY; CHEMOLUMINESCENCE; COMPLEX FORMATION; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME IMMOBILIZATION; ENZYME SUBSTRATE; EXCISION REPAIR; FLUORESCENCE ANALYSIS; GENOTOXICITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MICROTITER PLATE ASSAY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN ISOLATION; QUANTITATIVE STUDY; RESIDUE ANALYSIS; SENSITIVITY ANALYSIS;

CELL EXTRACTS; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MOLECULAR EPIDEMIOLOGY; MUTAGENS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; VALIDATION STUDIES AS TOPIC;

EID: 84864525248     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2012.05.002     Document Type: Article

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