An in vitro method to study the effects of thyroid hormone-disrupting chemicals on neuronal development

NeuroToxicology

Volumn 33, Issue 4, 2012, Pages 753-757

  Xiong, Yu ^a   Ibhazehiebo, Kingsley ^b,c   Iwasaki, Toshiharu ^b   Koibuchi, Noriyuki ^b  

^a GUNMA UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF BENIN   (Nigeria)

Author keywords

Brain development; Primary culture; Purkinje cell; Screening system; Thyroid hormone; Thyroid hormone receptor; Transcriptional regulation

Indexed keywords

DECABROMODIPHENYL ETHER; ENDOCRINE DISRUPTOR; THYROID HORMONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CHEMOLUMINESCENCE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENDRITIC CELL; DNA DETERMINATION; GENETIC ANALYSIS; HORMONE ACTION; HORMONE INHIBITION; IN VITRO STUDY; MOLECULAR DYNAMICS; NERVE CELL DIFFERENTIATION; NEWBORN; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PURKINJE CELL; RAT; REPORTER GENE;

ANIMALS; ANIMALS, NEWBORN; BINDING SITES; CELLS, CULTURED; CEREBELLUM; DENDRITES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; GENE EXPRESSION REGULATION; GENES, REPORTER; HALOGENATED DIPHENYL ETHERS; NEUROGENESIS; PURKINJE CELLS; RATS; THYROID HORMONE RECEPTORS BETA; THYROXINE; TOXICITY TESTS; TRANSCRIPTION, GENETIC; TRANSFECTION;

RATTUS;

EID: 84864521556     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.04.021     Document Type: Article

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