Prenatal ethanol exposure leads to greater ethanol-induced appetitive reinforcement

Alcohol

Volumn 46, Issue 6, 2012, Pages 585-593

  Pautassi, Ricardo M ^a,c   Nizhnikov, Michael E ^b   Spear, Norman E ^b   Molina, Juan C ^a,c  

^a INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

^b BINGHAMTON UNIVERSITY   (United States)

^c UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Aversion; Ethanol; Preference; Prenatal ethanol exposure; Second order conditioning

Indexed keywords

ALCOHOL; KAPPA OPIATE RECEPTOR; SACCHARIN;

ALCOHOL INTOXICATION; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GESTATION PERIOD; MALE; NONHUMAN; PLACE PREFERENCE; PREGNANCY; PRENATAL DRUG EXPOSURE; RAT; REINFORCEMENT; TASTE AVERSION;

ANIMALS; AVOIDANCE LEARNING; CONDITIONING, CLASSICAL; ETHANOL; FEMALE; MALE; MOTIVATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; RECEPTORS, OPIOID, KAPPA; REINFORCEMENT (PSYCHOLOGY);

RATTUS;

EID: 84864520290     PISSN: 07418329     EISSN: 18736823     Source Type: Journal    
DOI: 10.1016/j.alcohol.2012.05.004     Document Type: Article

References (40)

1. Abate P., Pepino M.Y., Dominguez H.D., Spear N.E., Molina J.C. Fetal associative learning mediated through maternal alcohol intoxication. Alcoholism: Clinical and Experimental Research 2000, 24:39-47.
2. Abate P., Pueta M., Spear N.E., Molina J.C. Fetal learning about ethanol and later ethanol responsiveness: evidence against " safe" amounts of prenatal exposure. Experimental Biology and Medicine 2008, 233:139-154.
3. Abate P., Spear N.E., Molina J.C. Fetal and infantile alcohol-mediated associative learning in the rat. Alcoholism: Clinical and Experimental Research 2001, 25:989-998.
4. Abel E.L., Bush R., Dintcheff B.A. Exposure of rats to alcohol in utero alters drug sensitivity in adulthood. Science 1981, 26:1531-1533.
5. Alati R., Mamum A.A., Williams G.M., O' Callaghan M., Najman J.M., Bor W. In utero alcohol exposure and prediction of alcohol disorders in early adulthood. Archives of General Psychiatry 2006, 63:1009-1016.
6. Arias C., Molina J.C., Mlewski E.C., Pautassi R.M., Spear N. Acute sensitivity and acute tolerance to ethanol in preweanling rats with or without prenatal experience with the drug. Pharmacology Biochemistry and Behavior 2008, 89:608-622.
7. Arias C., Pautassi R.M., Molina J.C., Spear N.E. A comparison between taste avoidance and conditioned disgust reactions induced by ethanol and lithium chloride in preweanling rats. Developmental Psychobiology 2010, 52:545-557.
8. Baer J.S., Sampson P.D., Barr H.M., Connor P.D., Streissguth A.P. A 21-year longitudinal analysis of the effects of prenatal alcohol exposure on young adult drinking. Archives of General Psychiatry 2003, 60:377-385.
9. Becker H.C., Weathersby R.T., Hale R.L. Prenatal ethanol exposure alters sensitivity to the effects of apomorphine given alone and in combination with ethanol on locomotor activity in adult male mouse offspring. Neurotoxicology and Teratology 1995, 17:57-64.
10. Campbell J.C., Szumlinski K.K., Kippin T.E. Contribution of early environmental stress to alcoholism vulnerability. Alcohol 2009, 43:547-554.
11. Chotro M.G., Arias C. Prenatal Exposure to ethanol increases ethanol consumption: a conditioned response?. Alcohol 2003, 30:19-28.
12. Chotro M.G., Arias C., Laviola G. Increased ethanol intake after prenatal ethanol exposure: studies with animals. Neuroscience and Biobehavioral Reviews 2007, 31:181-191.
13. Cunningham C.L., Fidler T.L., Hill K.G. Animal models of alcohol's motivational effects. Alcohol Research and Health 2000, 24:85-92.
14. Dellarosa Cummins D., Cummins R. Biological preparedness and evolutionary explanation. Cognition 1997, 73:B37-B53.
15. Díaz-Cenzano E., Chotro M.G. Prenatal binge ethanol exposure on gestation days 19-20, but not on days 17-18, increases postnatal ethanol acceptance in rats. Behavioral Neuroscience 2010, 124:362-369.
16. Gonzalez-Perez O., Gutiérrez-Smith Y., Guzmán-Muñiz J., Moy-López N.A. Intrauterine stress impairs spatial learning in the progeny of Wistar rats. Revista de Investigacion Clinica 2011, 63:279-286.
17. Harmon K.M., Greenwald M.L., McFarland A., Beckwith T., Cromwell H.C. The effects of prenatal stress on motivation in the rat pup. Stress 2009, 12:250-258.
18. Hosseini-Sharifabad M., Hadinedoushan H. Prenatal stress induces learning deficits and is associated with a decrease in granules and CA3 cell dendritic tree size in rat hippocampus. Anatomical Science International 2007, 82:211-217.
19. Land B.B., Bruchas M.R., Schattauer S., Giardino W.J., Aita M., Messinger D., et al. Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking. Proceedings of the National Academy of Science USA 2009, 106:19168-19173.
20. Lee P.R., Brady D.L., Shapiro R.A., Dorsa D.M., Koenig J.I. Prenatal stress generates deficits in rat social behavior: reversal by oxytocin. Brain Research 2007, 1156:152-167.
21. Miranda-Morales R.S., Molina J.C., Spear N.E., Abate P. Naloxone attenuation of ethanol-reinforced operant responding in infant rats in a re-exposure paradigm. Psychopharmacology 2012, 219:235-246.
22. Molina J.C., Pautassi R.M., Truxell E., Spear N.E. Differential motivational properties of ethanol during early ontogeny as a function of dose and postadministration time. Alcohol 2007, 41:41-55.
23. Molina J.C., Ponce L.F., Truxell E., Spear N.E. Infantile sensitivity to ethanol's motivational effects: ethanol reinforcement during the third postnatal week. Alcoholism: Clinical and Experimental Research 2006, 30:1506-1519.
24. Murawski N.J., Stanton M.E. Effects of dose and period of neonatal alcohol exposure on the context preexposure facilitation effect. Alcoholism: Clinical and Experimental Research 2011, 35:1160-1170.
25. National Research Council Guide for the care and use of laboratory animals 1996, National Academy Press, Washington, DC.
26. Nizhnikov M.E., Molina J.C., Varlinskaya E.I., Spear N.E. Prenatal ethanol exposure increases ethanol reinforcement in neonatal rats. Alcoholism: Clinical and Experimental Research 2006, 30:34-45.
27. Pautassi R.M., Myers M., Spear L.P., Molina J.C., Spear N.E. Adolescent but not adult rats exhibit ethanol-mediated appetitive second-order conditioning. Alcoholism: Clinical and Experimental Research 2008, 32:2016-2027.
28. Pautassi R.M., Myers M., Spear L.P., Molina J.C., Spear N.E. Ethanol induces second-order aversive conditioning in adolescent and adult rats. Alcohol 2011, 45:45-55.
29. Pautassi R.M., Nizhnikov M.E., Acevedo M.B., Spear N.E. Naloxone blocks ethanol-mediated appetitive conditioning and locomotor activation in adolescent rats. Behavioral Brain Research 2010, 216:262-269.
30. Pautassi R.M., Nizhnikov M.E., Acevedo M.B., Spear N.E. Early role of the κ opioid receptor in ethanol-induced reinforcement. Physiology and Behavior 2012, 105:1231-1241.
31. Pautassi R.M., Nizhnikov M.E., Fabio M.C., Spear N.E. Early maternal separation affects ethanol-induced conditioning in a nor-BNI insensitive manner, but does not alter ethanol-induced locomotor activity. Pharmacology Biochemistry and Behavior 2012, 100:630-638.
32. Pautassi R.M., Ponce L.F., Molina J.C. Efectos de la exposición temprana al etanol sobre subsiguientes aprendizajes mediados por los atributos incondicionales de la droga. Rev. Latinoam. Psicol. [Latin American Journal of Psychology] 2005, 37:131-149.
33. Pillai N.P., Ross D.H. Ethanol-induced hypothermia in rats: possible involvement of opiate kappa receptors. Alcohol 1986, 3:249-253.
34. Pohorecky L.A., Patel V., Roberts P. Effects of ethanol in an open field apparatus: modification by U50488H and WIN 44441-3. Physiology and Behavior 1989, 45:273-287.
35. Ponce L.F., Pautassi R.M., Spear N.E., Molina J.C. Ethanol-mediated operant learning in the infant rat leads to increased ethanol intake during adolescence. Pharmacology Biochemistry and Behavior 2008, 90:640-650.
36. Pueta M., Rovasio R.A., Abate P., Spear N.E., Molina J.C. Prenatal and postnatal ethanol experiences modulate consumption of the drug in rat pups, without impairment in the granular cell layer of the main olfactory bulb. Physiology and Behavior 2011, 102:63-75.
37. de Sanctis L., Memo L., Pichini S., Tarani L., Vagnarelli F. Fetal alcohol syndrome: new perspectives for an ancient and underestimated problem. Journal of Maternal-Fetal and Neonatal Medicine 2011, 24(Suppl. 1):34-37.
38. Spear N.E., Molina J.C. Fetal or infantile exposure to ethanol promotes ethanol ingestion in adolescence and adulthood: a theoretical review. Alcoholism: Clinical and Experimental Research 2005, 29:909-929.
39. Truxell E.M., Molina J.C., Spear N.E. Ethanol intake in the juvenile, adolescent, and adult rat: effects of age and prior exposure to ethanol. Alcoholism: Clinical and Experimental Research 2007, 31:755-765.
40. Yates W.R., Cadoret R.J., Troughton E.P., Stewart M., Giunta T.S. Effect of fetal alcohol exposure on adult symptoms of nicotine, alcohol, and drug dependence. Alcoholism: Clinical and Experimental Research 1998, 22:914-920.