Use of UV-C radiation to disinfect non-critical patient care items: A laboratory assessment of the Nanoclave Cabinet

BMC Infectious Diseases

Volumn 12, Issue , 2012, Pages

  Moore, Ginny ^a   Ali, Shanom ^a   Cloutman Green, Elaine A ^b   Bradley, Christina R ^c   Wilkinson, Martyn AC ^c   Hartley, John C ^b   Fraise, Adam P ^c   Wilson, A Peter R ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Adenovirus; Nosocomial pathogens; Surface disinfection; Ultraviolet radiation

Indexed keywords

BENZALKONIUM CHLORIDE; DISINFECTANT AGENT; PEROXIDE; VIRUS DNA;

ACINETOBACTER BAUMANNII; ADENOVIRUS; ARTICLE; BACTERIAL COUNT; BACTERIAL LOAD; BACTERIAL SPORE; BACTERIAL SURVIVAL; BACTERIUM CONTAMINATION; BLOOD PRESSURE CUFF; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; DISINFECTION; DNA DEGRADATION; ENTEROCOCCUS HIRAE; ESCHERICHIA COLI; INSTRUMENT STERILIZATION; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; NONHUMAN; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; RADIATION EQUIPMENT; SOIL; ULTRAVIOLET C RADIATION; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ADENOVIRIDAE; CLOSTRIDIUM DIFFICILE; COLONY COUNT, MICROBIAL; DISINFECTION; DNA, VIRAL; ENVIRONMENTAL MICROBIOLOGY; EQUIPMENT AND SUPPLIES; HUMANS; MICROBIAL VIABILITY; POLYMERASE CHAIN REACTION; SPORES, BACTERIAL; ULTRAVIOLET RAYS;

EID: 84864515315     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-12-174     Document Type: Article

References (28)

1. Sexton T, Clarke P, O'Neill EO, Dillane T, Humphreys H. Environmental reservoirs of methicillin-resistant Staphylococcus aureus in isolation rooms: correlation with patient isolates and implications for hospital hygiene. J Hosp Infect 2006, 62:187-194. 10.1016/j.jhin.2005.07.017, 16290319.
2. Hayden MK, Bonten MJM, Blom DW, Lyle EA, van de Vijver DAMC, Weinstein RA. Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures. Clin Infect Dis 2006, 42:1552-1560. 10.1086/503845, 16652312.
3. Manian FA, Meyer L, Jenne J. Clostridium difficile contamination of blood pressure cuffs: a call for a closer look at gloving practices in the era of universal precautions. Infect Control Hosp Epidemiol 1996, 17:180-182. 10.1086/647271, 8708361.
4. Rutala WA. Disinfection and sterilization of patient-care items. Infect Control Hosp Epidemiol 1996, 17:377-384. 10.1086/647324, 8805073.
5. Gould D. The fall and rise of cleanliness in British healthcare and the nursing contribution. J Res Nurs 2005, 10:495-509.
6. Walker N, Gupta R, Cheesbrough J. Blood pressure cuffs: friend or foe?. J Hosp Infect 2006, 63:167-169. 10.1016/j.jhin.2005.10.019, 16616799.
7. Hijnen WAM, Beerendonk EF, Medema GJ. Inactivation credit of UV radiation for viruses, bacteria and protozoan (oo)cysts in water: A review. Wat Res 2006, 40:3-22.
8. Andersen BM, Bånrud H, Bøe E, Bjordal O, Drangsholt F. Comparison of UV C light and chemicals for disinfection of surfaces in hospital isolation rooms. Infect Control Hosp Epidemiol 2006, 27:729-734. 10.1086/503643, 16807849.
9. Nerandzic MM, Cadnum JL, Pultz MJ, Donskey CJ. Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. BMC Infect Dis 2010, 10:197-204. 10.1186/1471-2334-10-197, 2910020, 20615229.
10. Rutala WA, Gergen MF, Weber DJ. Room decontamination with UV radiation. Infect Control Hosp Epidemiol 2010, 31:1025-1029. 10.1086/656244, 20804377.
11. Rastogi VK, Wallace L, Smith LS. Disinfection of Acinetobacter baumannii-contaminated surfaces relevant to medical treatment facilities with ultraviolet C light. Military Med 2007, 11:1166-1169.
12. Shetty N, Srinivasan S, Holton J, Ridgway GL. Evaluation of microbicidal activity of a new disinfectant: Sterilox 2500 against Clostridium difficile spores, Helicobacter pylori, vancomycin resistant Enterococcus species, Candida albicans and several Mycobacterium species. J Hosp Infect 1999, 41:101-105. 10.1016/S0195-6701(99)90046-4, 10063471.
13. Heim A, Ebnet C, Harste G, Pring-Akerblom P. Rapid and quantitative detection of human Adenovirus DNA by real-time PCR. J Med Virol 2003, 70:228-239. 10.1002/jmv.10382, 12696109.
14. Mitchell A, DeAlwis N, Collins J, Chew K, Taylor R, Schwa U, Narayanan M. Stethoscope or 'staphoscope'? Infection by auscultation. J Hosp Infect 2010, 76:278-279. 10.1016/j.jhin.2010.06.015, 20692728.
15. Porwancher R, Sheth A, Remphrey S, Taylor E, Hinkle C, Zervos M. Epidemiological study of hospital-acquired infection with vancomycin-resistant Enterococcus faecium: Possible transmission by an electronic ear-probe thermometer. Infect Control Hosp Epidemiol 1997, 18:771-773. 10.1086/647535, 9397374.
16. Rutala WA, White MS, Gergen MF, Weber DJ. Bacterial contamination of keyboards: efficacy and functional impact of disinfectants. Infect Control Hosp Epidemiol 2006, 27:372-377. 10.1086/503340, 16622815.
17. Cefai C, Elliot TSJ. Re-usable ECG electrodes - a vehicle for cross-infection?. J Hosp Infect 1988, 12:65-67. 10.1016/0195-6701(88)90124-7, 2905376.
18. Creamer E, Humphreys H. The contribution of beds to healthcare-associated infection: the importance of adequate decontamination. J Hosp Infect 2008, 69:8-23. 10.1016/j.jhin.2008.01.014, 18355943.
19. Sattar SA. Promises and pitfalls of recent advances in chemical means of preventing the spread of nosocomial infections by environmental surfaces. Am J Infect Control 2010, 38:S34-S40. 10.1016/j.ajic.2010.04.207, 20569854.
20. Casey AL, Adams D, Karpanen TJ, Lambert PA, Cookson BD, Nightingale P, Miruszenko L, Shillam R, Christian P, Elliott TSJ. Role of copper in reducing hospital environment contamination. J Hosp Infect 2010, 74:72-77. 10.1016/j.jhin.2009.08.018, 19931938.
21. Otter JA, Cummins M, Ahmad F, van Tonder C, Drabu YJ. Assessing the biological efficacy and rate of recontamination following hydrogen peroxide vapour decontamination. J Hosp Infect 1997, 67:182-188.
22. Medicine and Healthcare Products Regulatory Agency Medical device alert (MDA/2007/034) 2007, , London, Medicine and Healthcare Products Regulatory Agency.
23. Gritz DC, Lee TY, McDonnell PJ, Shih K, Baron N. Ultraviolet radiation for the sterilization of contact lenses. Eye Contact Lens 1990, 16:294-298.
24. Büttgen S, Gebel J, Hornei B, Engelhart S, Koch ONJ, Exner M. Comparison of chemo resistance of Clostridium difficile ribotype 027 spores and Bacillus subtilis spores against disinfectants. Hyg Med 2008, 33:513-517.
25. Snelling AM, Beggs CB, Kerr KG, Shepherd SJ. Spores of Clostridium difficile in hospital air. Clin Infect Dis 2010, 51:1104-1105. 10.1086/656686, 20925506.
26. Moisan M, Barbeau J, Moreau S, Pelletier J, Tabrizian M, Yahia LH. Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms. Int J Pharm 2001, 226:1-21. 10.1016/S0378-5173(01)00752-9, 11532565.
27. Humphreys PN. Testing standards for sporicides. J Hosp Infect 2011, 77:193-198. 10.1016/j.jhin.2010.08.011, 21122947.
28. Hijnen WAM, Beerendonk EF, Medema GJ. Inactivation credit of UV radiation for viruses, bacteria and protozoan (oo)cysts in water. Water Res 2006, 40:3-22. 10.1016/j.watres.2005.10.030, 16386286.