The effect of artificial rearing on gut microbiota in a mouse pup-in-a-cup model

Experimental Animals

Volumn 61, Issue 4, 2012, Pages 453-460

  Zeng, Benhua ^a   Yuan, Jing ^a   Li, Wenxia ^a   Tang, Huan ^a   Wei, Hong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Artificially reared; Gut microbiota; PCR DGGE; Pup in a cup

Indexed keywords

RNA 16S;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL MILK; BODY GROWTH; CLUSTER ANALYSIS; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; DIGESTIVE TRACT INTUBATION; EXPERIMENTAL MOUSE; GENE EXPRESSION PROFILING; INTESTINE FLORA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PUP (RODENT); REARING; RNA FINGERPRINTING; RNA SEQUENCE; SEQUENCE HOMOLOGY; TUBE FEEDING;

ANIMAL HUSBANDRY; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; ANIMALS, NEWBORN; BACTERIA; CLUSTER ANALYSIS; DENATURING GRADIENT GEL ELECTROPHORESIS; FECES; INTUBATION, GASTROINTESTINAL; MATERNAL DEPRIVATION; MICE; MICE, INBRED C57BL; MILK SUBSTITUTES; PHYLOGENY; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; SPECIFIC PATHOGEN-FREE ORGANISMS; STOMACH;

MUS;

EID: 84864508017     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.61.453     Document Type: Article

References (24)

1. Beierle, E.A., Chen, M.K., Hartwich, J.E., Iyengar, M., Dai, W., Li, N., Demarco, V., and Neu, J. 2004. Artificial rearing of mouse pups: development of a mouse pup-in-a-cup model. Pediatr. Res. 56: 250-255. [Medline] [CrossRef]
2. Chatterjee, D., Chatterjee-Chakraborty, M., Rees, S., Cauchi, J., de Medeiros, C.B., and Fleming, A.S. 2007. Maternal isolation alters the expression of neural proteins during development: 'Stroking' stimulation reverses these effects. Brain Res. 1158: 11-27. [Medline] [CrossRef]
3. Dimmitt, R.A., Staley, E.M., Chuang, G., Tanner, S.M., Soltau, T.D., and Lorenz, R.G. 2010. Role of postnatal acquisition of the intestinal microbiome in the early development of immune function. J. Pediatr. Gastroenterol. Nutr. 51: 262-273. [Medline]
4. Dvorak, B., McWilliam, D.L., Williams, C.S., Dominguez, J.A., Machen, N.W., McCuskey, R.S., and Philipps, A.F. 2000. Artificial formula induces precocious maturation of the small intestine of artificially reared suckling rats. J. Pediatr. Gastroenterol. Nutr. 31: 162-169. [Medline] [CrossRef]
5. Francis, D.D., Diorio, J., Plotsky, P.M., and Meaney, M.J. 2002. Environmental enrichment reverses the effects of maternal separation on stress reactivity. J. Neurosci. 22: 7840-7843. [Medline]
6. Gafan, G.P., Lucas, V.S., Roberts, G.J., Aarons, L., Ashley, M.P., Hull, P.S., and McBain, A.J. 2005. Statistical analyses of complex denaturing gradient gel electrophoresis profiles. J. Clin. Microbiol. 43: 3971-3978. [Medline] [CrossRef]
7. Guarner, F. and Malagelada, J.R. 2003. Gut flora in health and disease. Lancet 361: 512-519. [Medline] [CrossRef]
8. Hall, W.G. 1975. Weaning and growth of artificially reared rats. Science 190: 1313-1315. [Medline] [CrossRef]
9. Isolauri, E., Kalliomaki, M., Laitinen, K., and Salminen, S. 2008. Modulation of the maturing gut barrier and microbiota: a novel target in allergic disease. Curr. Pharm. Des. 14: 1368-1375. [Medline] [CrossRef]
10. Ley, R.E., Backhed, F., Turnbaugh, P., Lozupone, C.A., Knight, R.D., and Gordon, J.I. 2005. Obesity alters gut microbial ecology. Proc. Natl. Acad. Sci. U.S.A. 102: 11070-11075. [Medline] [CrossRef]
11. Muyzer, G., de Waal, E.C., and Uitterlinden, A.G. 1993. Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. Appl. Environ. Microbiol. 59: 695-700. [Medline]
12. Patel, M.S. and Hiremagalur, B.K. 1992. Artificial-rearing technique: its usefulness in nutrition research. J. Nutr. 122: 412-419. [Medline]
13. Patel, M.S., Srinivasan, M., and Laychock, S.G. 2009. Metabolic programming: role of nutrition in the immediate postnatal life. J. Inherit. Metab. Dis. 32: 218-228. [Medline] [CrossRef]
14. Penders, J., Thijs, C., Vink, C., Stelma, F.F., Snijders, B., Kummeling, I., van den Brandt, P.A., and Stobberingh, E.E. 2006. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 118: 511-521. [Medline] [CrossRef]
15. Penders, J., Vink, C., Driessen, C., London, N., Thijs, C., and Stobberingh, E.E. 2005. Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by real-time PCR. FEMS Microbiol. Lett. 243: 141-147. [Medline] [CrossRef]
16. Plotsky, P.M., Thrivikraman, K.V., Nemeroff, C.B., Caldji, C., Sharma, S., and Meaney, M.J. 2005. Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology 30: 2192-2204. [Medline] [CrossRef]
17. Pryce, C.R., Bettschen, D., Bahr, N.I., and Feldon, J. 2001. Comparison of the effects of infant handling, isolation, and nonhandling on acoustic startle, prepulse inhibition, locomotion, and HPA activity in the adult rat. Behav. Neurosci. 115: 71-83. [Medline] [CrossRef]
18. Rhees, R.W., Lephart, E.D., and Eliason, D. 2001. Effects of maternal separation during early postnatal development on male sexual behavior and female reproductive function. Behav. Brain Res. 123: 1-10. [Medline] [CrossRef]
19. Schmidt, M., Okimoto, D.K., Dent, G.W., Gordon, M.K., and Levine, S. 2002. Maternal regulation of the hypothalamic-pituitary-adrenal axis in the 20-day-old rat: consequences of laboratory weaning. J. Neuroendocrinol. 14: 450-457. [Medline] [CrossRef]
20. West, J.R. 1993. Use of pup-in-a-cup model to study brain development. J. Nutr. 123: 382-385. [Medline]
21. Yajima, M., Hoshiba, J., Terahara, M., and Yajima, T. 2007. Reduced thymic size and numbers of splenic CD4+ and CD8+ cells in artificially reared mouse pups. Biosci. Biotechnol. Biochem. 71: 2420-2427. [Medline] [CrossRef]
22. Yajima, M., Kanno, T., and Yajima, T. 2006. A chemically derived milk substitute that is compatible with mouse milk for artificial rearing of mouse pups. Exp. Anim. 55: 391-397. [Medline] [CrossRef]
23. Yajima, M., Nakayama, M., Hatano, S., Yamazaki, K., Aoyama, Y., Yajima, T., and Kuwata, T. 2001. Bacterial translocation in neonatal rats: the relation between intestinal flora, translocated bacteria, and influence of milk. J. Pediatr. Gastroenterol. Nutr. 33: 592-601. [Medline] [CrossRef]
24. Yuan, J., Wei, H., Zeng, B., Tang, H., Li, W., and Zhang, Z. 2010. Impact of neonatal antibiotic treatment on the biodiversity of the murine intestinal Lactobacillus community. Curr. Microbiol. 60: 6-11. [Medline] [CrossRef]