Overexpressing transcriptional regulator in Chaetomium globosum activates a silent biosynthetic pathway: Evaluation of shanorellin biosynthesis

Journal of Antibiotics

Volumn 65, Issue 7, 2012, Pages 377-380

  Tsunematsu, Yuta ^a   Ichinoseki, Suguru ^a   Nakazawa, Takehito ^a   Ishikawa, Noriyasu ^a   Noguchi, Hiroshi ^a   Hotta, Kinya ^b   Watanabe, Kenji ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

biosynthesis; fungi; PKS; silent gene cluster; transcriptional regulator

Indexed keywords

DNA; HYGROMYCIN; QUINONE DERIVATIVE; SHANORELLIN; UNCLASSIFIED DRUG;

ARTICLE; CHAETOMIUM; CHAETOMIUM GLOBOSUM; DNA SEQUENCE; DRUG SYNTHESIS; GENE CLUSTER; GENE OVEREXPRESSION; HETERONUCLEAR MULTIPLE BOND CORRELATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSCRIPTION REGULATION;

BENZOQUINONES; BIOSYNTHETIC PATHWAYS; CHAETOMIUM; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; MULTIGENE FAMILY; POLYKETIDES; TRANSCRIPTION FACTORS;

CHAETOMIUM GLOBOSUM; FUNGI;

EID: 84864482614     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2012.34     Document Type: Article

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