Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression

Prostaglandins and Other Lipid Mediators

Volumn 98, Issue 3-4, 2012, Pages 122-128

  Marcantoni, Emanuela ^a   Di Francesco, Luigia ^a   Totani, Licia ^b   Piccoli, Antonio ^b   Evangelista, Virgilio ^b   Tacconelli, Stefania ^a   Patrignani, Paola ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b 66030 Santa Maria Imbaro ^*  (Italy)

Author keywords

17 Estradiol; Cyclooxygenase 2; Heme oxygenase 1; HUVEC; Prostacyclin

Indexed keywords

CYCLOOXYGENASE 2; ESTRADIOL; HEME OXYGENASE 1; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTANOID;

ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM; HUMAN; HUMAN CELL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SHEAR STRESS; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

CYCLOOXYGENASE 2; ESTROGENS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PROSTAGLANDINS; RNA, MESSENGER; STRESS, MECHANICAL;

EID: 84864457674     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2012.01.006     Document Type: Article

References (40)

1. M.E. Mendelsohn Protective effects of estrogen on the cardiovascular system Am J Cardiol 89 2002 12E 17E
2. M.K. Hong, P.A. Romm, K. Reagan, C.E. Green, and C.E. Rackley Effects of estrogen replacement therapy on serum lipid values and angiographically defined coronary artery disease in postmenopausal women Am J Cardiol 69 1992 176 178
3. R. Erkkola, R. Lammintausta, R. Punnonen, and L. Rauramo The effect of estriol succinate therapy on plasma renin activity and urinary aldosterone in postmenopausal women Maturitas 1 1978 9 14
4. H. Schunkert, A.H. Danser, H.W. Hense, F.H. Derkx, S. Kürzinger, and G.A. Riegger Effects of estrogen replacement therapy on the renin-angiotensin system in postmenopausal women Circulation 95 1997 39 45
5. K. Sugioka, Y. Shimosegawa, and M. Nakano Estrogens as natural antioxidants of membrane phospholipid peroxidation FEBS Lett 210 1987 37 39
6. 2+ uptake Circ Res 81 1997 242 248
7. C.W. Jiang, P.M. Sarrel, D.C. Lindsay, P.A. Poole-Wilson, and P. Collins Endothelium-independent relaxation of rabbit coronary artery by 17 beta-oestradiol in vitro Br J Pharmacol 104 1991 1033 1037
8. R.L. Lantin-Hermoso, C.R. Rosenfeld, I.S. Yuhanna, Z. German, Z. Chen, and P.W. Shaul Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium Am J Physiol 273 1997 L119 L126
9. 2+ mobilization Circ Res 81 1997 885 892
10. K.M. Egan, J.A. Lawson, and S. Fries COX-2-derived prostacyclin confers atheroprotection on female mice Science 306 2004 1954 1957
11. T. Prestera, P. Talalay, J. Alam, Y.I. Ahn, P.J. Lee, and A.M. Choi Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE) Mol Med 1 1995 827 837
12. N.G. Abraham, J. Cao, D. Sacerdoti, X. Li, and G. Drummond Heme oxygenase: the key to renal function regulation Am J Physiol Renal Physiol 297 2009 F1137 F1152
13. S. Novella, and C. Hermenegildo Fulya Akin Estradiol regulation of prostanoids production in endothelium, basic and clinical endocrinology up-to-date 2011 InTech 978-953-307-340-8 http://www.intechopen.com/articles/ show/title/estradiol-regulation-of-prostanoids-production-in-endothelium
14. E.C. Turner, and B.T. Kinsella Estrogen increases expression of the human prostacyclin receptor within the vasculature through an ERα-dependent mechanism J Mol Biol 396 2010 473 486
15. M. Braddock, J.L. Schwachtgen, P. Houston, M.C. Dickson, M.J. Lee, and C.J. Campbell Fluid shear stress modulation of gene expression in endothelial cells Physiology 13 1998 241 246
16. J.N. Topper, J. Cai, D. Falb, and M.A. Gimbrone Jr. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress Proc Natl Acad Sci USA 93 1996 10417 10422
17. H. Inoue, Y. Taba, Y. Miwa, C. Yokota, M. Miyagi, and T. Sasaguri Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells Arterioscler Thromb Vasc Biol 22 2002 1415 1420
18. L. Di Francesco, L. Totani, and M. Dovizio Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis fact or-α biosynthesis via heme oxygenase-1 in human endothelial cells Circ Res 104 2009 506 513
19. K.R. Bley, A. Bhattacharya, and D.V. Daniels RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists Br J Pharmacol 147 2006 335 345
20. M.A. Gimbrone Jr. Culture of vascular endothelium Prog Hemost Thromb 3 1976 1 28
21. J.A. Frangos, L.V. McIntire, and S.G. Eskin Shear stress induced stimulation of mammalian cell metabolism Biotechnol Bioeng 32 1998 1053 1060
22. J.A. Maier, T. Hla, and T. Maciag Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells J Biol Chem 265 1990 10805 10808
23. P. Patrignani, M.R. Panara, and A. Greco Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases J Pharmacol Exp Ther 271 1994 1705 1712
24. 2 through cAMP Mediat Inflamm 8 1999 287 294
25. K.A. Harper, and A.J. Tyson-Capper Complexity of COX-2 gene regulation Biochem Soc Trans 36 2008 543 545
26. S.S. Jun, Z. Chen, M.C. Pace, and P.W. Shaul Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium Clin Invest 102 1998 176 183
27. T. Mikkola, P. Turunen, K. Avela, A. Orpana, L. Viinikka, and O. Ylikorkala 17 beta-estradiol stimulates prostacyclin, but not endothelin-1, production in human vascular endothelial cells J Clin Endocrinol Metab 80 1995 1832 1836
28. 2 and NO in endothelial cells Maturitas 25 1996 141 147
29. A. Sobrino, P.J. Oviedo, and S. Novella Estradiol selectively stimulates endothelial prostacyclin production through estrogen receptor-{alpha} J Mol Endocrinol 44 2010 237 246
30. A.O. Mueck, H. Seeger, and D. Wallwiener Medroxyprogesterone acetate versus norethisterone: effect on estradiol-induced changes of markers for endothelial function and atherosclerotic plaque characteristics in human female coronary endothelial cell cultures Menopause 9 2002 273 281
31. J.N. Topper, J. Cai, and G. Stavrakis Human prostaglandin transporter gene (hPGT) is regulated by fluid mechanical stimuli in cultured endothelial cells and expressed in vascular endothelium in vivo Circulation 98 1998 2396 2403
32. L.E. Young, and D.A. Dixon Posttranscriptional regulation of cyclooxygenase 2 expression in colorectal cancer Curr Colorectal Cancer Rep 6 2010 60 67
33. D.A. Dixon, C.D. Kaplan, T.M. McIntyre, G.A. Zimmerman, and S.M. Prescott Post-transcriptional control of cyclooxygenase-2 gene expression J Biol Chem 275 2000 11750 11757
34. D.A. Dixon, N.D. Tolley, and K. Bemis-Standoli Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling J Clin Invest 116 2006 2727 2738
35. J.M. Hall, J.F. Couse, and K.S. Korach The multifaceted mechanisms of estradiol and estrogen receptor signaling J Biol Chem 276 2001 36869 36872
36. J. Favre, J. Gao, and J.P. Henry Endothelial estrogen receptor {alpha} plays an essential role in the coronary and myocardial protective effects of estradiol in ischemia/reperfusion Arterioscler Thromb Vasc Biol 30 2010 2562 2567
37. L. Novensà, S. Novella, and P. Medina Aging negatively affects estrogens-mediated effects on nitric oxide bioavailability by shifting ERα/ERβ balance in female mice PLoS One 6 2011 e25335
38. A. Foryst-Ludwig, M. Clemenz, and S. Hohmann Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma PLoS Genet 4 2008 e1000108
39. G. Krönke, A. Kadl, and E. Ikonomu Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors Arterioscler Thromb Vasc Biol 27 2007 1276 1282
40. J.E. Rossouw, G.L. Anderson, and R.L. Prentice Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial JAMA 288 2002 321 333