Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening

Journal of the American Chemical Society

Volumn 134, Issue 30, 2012, Pages 12732-12741

  Krauson, Aram J ^a   He, Jing ^a   Wimley, William C ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; BI-LAYER; CARBOXYL-TERMINAL; COMBINATORIAL PEPTIDE LIBRARIES; HIGH-THROUGHPUT; HIGH-THROUGHPUT ASSAYS; HIGH-THROUGHPUT SCREENING; LIBRARY SEQUENCES; MELITTIN; PEPTIDE TOXIN; PORE FORMATION; POTENTIAL APPLICATIONS; SELF-ASSEMBLE; STRUCTURAL INFORMATION; SURFACE BOUNDS; SYNTHETIC LIPID;

AMINO ACIDS; LIPID BILAYERS; ORTHOGONAL FUNCTIONS;

PEPTIDES;

MELITTIN; PROLINE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; COMBINATORIAL LIBRARY; HIGH THROUGHPUT SCREENING; PEPTIDE LIBRARY; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SURFACE PROPERTY;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; HIGH-THROUGHPUT SCREENING ASSAYS; MELITTEN; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PHOSPHOLIPIDS; UNILAMELLAR LIPOSOMES;

EID: 84864456742     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3042004     Document Type: Article

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