SCOPUS 정보 검색 플랫폼

Journal of the American Chemical Society

Volumn 131, Issue 22, 2009, Pages 7609-7617

Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: The importance of interfacial activity

(3) Rathinakumar, Ramesh a Walkenhorst, William F b Wimley, William C a

a TULANE UNIVERSITY HEALTH SCIENCES CENTER (United States)

b LOYOLA UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; BIOLOGICAL ACTIVITIES; COMBINATORIAL DESIGN; COMBINATORIAL LIBRARY; D-AMINO ACID; HIGH-THROUGHPUT SCREENING; IN-VITRO; IN-VIVO; INTERFACIAL ACTIVITY; MAMMALIAN CELLS; MECHANISM OF ACTION; MEMBRANE INTERFACE; MEMBRANE PERMEABILIZATION; NATURAL MEMBRANES; NET CHARGES; PEPTIDE LIBRARY; SECONDARY STRUCTURES; SEQUENCE MOTIFS; SYNTHETIC LIPID; WELL-DEFINED STRUCTURES;

AMINO ACIDS; BACTERIA; BACTERIOLOGY; BIOACTIVITY; BIOLOGICAL MEMBRANES; MAMMALS; ORGANIC ACIDS; PEPTIDES;

AMINES;

DEXTRO AMINO ACID; POLYPEPTIDE ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; PEPTIDE LIBRARY;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; DRUG STRUCTURE; FUNGUS; HEMOLYSIS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; MEMBRANE PERMEABILITY; NONHUMAN; PROTEIN SECONDARY STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; CELL STRAIN 3T3; CHEMISTRY; CIRCULAR DICHROISM; CRYPTOCOCCUS NEOFORMANS; DRUG EFFECT; ESCHERICHIA COLI; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; MOUSE; PSEUDOMONAS AERUGINOSA; SHEEP; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; COMBINATORIAL CHEMISTRY TECHNIQUES; CRYPTOCOCCUS NEOFORMANS; ESCHERICHIA COLI; HUMANS; MEMBRANE POTENTIALS; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; PEPTIDE LIBRARY; PSEUDOMONAS AERUGINOSA; SHEEP; STAPHYLOCOCCUS AUREUS;

EID: 67650566598 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja8093247 Document Type: Article

Times cited : (277)

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