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Volumn 18, Issue 28, 2012, Pages 3627-3634

Metabolic syndrome after liver transplantation: Preventable illness or common consequence?

Author keywords

Diabetes mellitus; Dyslipidemias; Hypertension; Immunosuppression; Liver transplantation; Metabolic syndrome X; Obesity

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; RAPAMYCIN; TACROLIMUS; TRIACYLGLYCEROL;

EID: 84864447614     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v18.i28.3627     Document Type: Editorial
Times cited : (34)

References (88)
  • 4
    • 0028856817 scopus 로고
    • Metabolic complications after liver transplantation. Diabetes, hypercholesterolemia, hypertension, and obesity
    • Stegall MD, Everson G, Schroter G, Bilir B, Karrer F, Kam I. Metabolic complications after liver transplantation. Diabetes, hypercholesterolemia, hypertension, and obesity. Transplantation 1995; 60: 1057-1060
    • (1995) Transplantation , vol.60 , pp. 1057-1060
    • Stegall, M.D.1    Everson, G.2    Schroter, G.3    Bilir, B.4    Karrer, F.5    Kam, I.6
  • 7
    • 57849130369 scopus 로고    scopus 로고
    • Metabolic syndrome in liver transplantation: Relation to etiology and immunosuppression
    • Bianchi G, Marchesini G, Marzocchi R, Pinna AD, Zoli M. Metabolic syndrome in liver transplantation: relation to etiology and immunosuppression. Liver Transpl 2008; 14: 1648-1654
    • (2008) Liver Transpl , vol.14 , pp. 1648-1654
    • Bianchi, G.1    Marchesini, G.2    Marzocchi, R.3    Pinna, A.D.4    Zoli, M.5
  • 10
    • 79251488789 scopus 로고    scopus 로고
    • Metabolic syndrome in liver transplant recipients: Prevalence, risk factors, and association with cardiovascular events
    • Laish I, Braun M, Mor E, Sulkes J, Harif Y, Ben Ari Z. Metabolic syndrome in liver transplant recipients: prevalence, risk factors, and association with cardiovascular events. Liver Transpl 2011; 17: 15-22
    • (2011) Liver Transpl , vol.17 , pp. 15-22
    • Laish, I.1    Braun, M.2    Mor, E.3    Sulkes, J.4    Harif, Y.5    Ben Ari, Z.6
  • 11
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the third National Health and Nutrition Examination Survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002; 287: 356-359
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 12
    • 0037126526 scopus 로고    scopus 로고
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report
    • Third Report of the National Cholesterol Education Program (NCEP)
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143-3421
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 13
    • 77952902738 scopus 로고    scopus 로고
    • Evolution of causes and risk factors for mortality post-liver transplant: Results of the NIDDK long-term followup study
    • Watt KD, Pedersen RA, Kremers WK, Heimbach JK, Charlton MR. Evolution of causes and risk factors for mortality post-liver transplant: results of the NIDDK long-term followup study. Am J Transplant 2010; 10: 1420-1427
    • (2010) Am J Transplant , vol.10 , pp. 1420-1427
    • Watt, K.D.1    Pedersen, R.A.2    Kremers, W.K.3    Heimbach, J.K.4    Charlton, M.R.5
  • 15
    • 0033797838 scopus 로고    scopus 로고
    • Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: A casecontrol study
    • Poonawala A, Nair SP, Thuluvath PJ. Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a casecontrol study. Hepatology 2000; 32: 689-692
    • (2000) Hepatology , vol.32 , pp. 689-692
    • Poonawala, A.1    Nair, S.P.2    Thuluvath, P.J.3
  • 16
    • 33645554182 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and liver transplantation
    • Angulo P. Nonalcoholic fatty liver disease and liver transplantation. Liver Transpl 2006; 12: 523-534
    • (2006) Liver Transpl , vol.12 , pp. 523-534
    • Angulo, P.1
  • 17
    • 11144264156 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A review of current understanding and future impact
    • Charlton M. Nonalcoholic fatty liver disease: a review of current understanding and future impact. Clin Gastroenterol Hepatol 2004; 2: 1048-1058
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 1048-1058
    • Charlton, M.1
  • 18
    • 84864457170 scopus 로고    scopus 로고
    • Organ Procurement and Transplantation Network (OPTN) and Scientific Registry of Transplant Recipients (SRTR)
    • Rockville, MD: Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation
    • Organ Procurement and Transplantation Network (OPTN) and Scientific Registry of Transplant Recipients (SRTR). OPTN/SRTR 2010 Annual Data Report. Rockville, MD: Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation; 2011
    • (2011) OPTN/SRTR 2010 Annual Data Report
  • 20
    • 2542546652 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss
    • Dixon JB, Bhathal PS, Hughes NR, O'Brien PE. Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss. Hepatology 2004; 39: 1647-1654
    • (2004) Hepatology , vol.39 , pp. 1647-1654
    • Dixon, J.B.1    Bhathal, P.S.2    Hughes, N.R.3    O'Brien, P.E.4
  • 28
    • 65449152558 scopus 로고    scopus 로고
    • American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults
    • Donnelly JE, Blair SN, Jakicic JM, Manore MM, Rankin JW, Smith BK. American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc 2009; 41: 459-471
    • (2009) Med Sci Sports Exerc , vol.41 , pp. 459-471
    • Donnelly, J.E.1    Blair, S.N.2    Jakicic, J.M.3    Manore, M.M.4    Rankin, J.W.5    Smith, B.K.6
  • 29
    • 33749265114 scopus 로고    scopus 로고
    • Aerobic capacity, muscle strength and health-related quality of life before and after orthotopic liver transplantation: Preliminary data of an Austrian transplantation centre
    • Pieber K, Crevenna R, Nuhr MJ, Quittan M, Peck-Radosavljevic M, Fialka-Moser V, Wiesinger GF. Aerobic capacity, muscle strength and health-related quality of life before and after orthotopic liver transplantation: preliminary data of an Austrian transplantation centre. J Rehabil Med 2006; 38: 322-328
    • (2006) J Rehabil Med , vol.38 , pp. 322-328
    • Pieber, K.1    Crevenna, R.2    Nuhr, M.J.3    Quittan, M.4    Peck-Radosavljevic, M.5    Fialka-Moser, V.6    Wiesinger, G.F.7
  • 33
    • 0025808662 scopus 로고
    • Excessive weight gain after liver transplantation
    • Palmer M, Schaffner F, Thung SN. Excessive weight gain after liver transplantation. Transplantation 1991; 51: 797-800
    • (1991) Transplantation , vol.51 , pp. 797-800
    • Palmer, M.1    Schaffner, F.2    Thung, S.N.3
  • 37
    • 0034964914 scopus 로고    scopus 로고
    • Beneficial effects of converting liver transplant recipients from cyclosporine to tacrolimus on blood pressure, serum lipids, and weight
    • Neal DA, Gimson AE, Gibbs P, Alexander GJ. Beneficial effects of converting liver transplant recipients from cyclosporine to tacrolimus on blood pressure, serum lipids, and weight. Liver Transpl 2001; 7: 533-539
    • (2001) Liver Transpl , vol.7 , pp. 533-539
    • Neal, D.A.1    Gimson, A.E.2    Gibbs, P.3    Alexander, G.J.4
  • 39
    • 0033610677 scopus 로고    scopus 로고
    • The effects of maintenance doses of FK506 versus cyclosporin A on glucose and lipid metabolism after orthotopic liver transplantation
    • Fernandez LA, Lehmann R, Luzi L, Battezzati A, Angelico MC, Ricordi C, Tzakis A, Alejandro R. The effects of maintenance doses of FK506 versus cyclosporin A on glucose and lipid metabolism after orthotopic liver transplantation. Transplantation 1999; 68: 1532-1541
    • (1999) Transplantation , vol.68 , pp. 1532-1541
    • Fernandez, L.A.1    Lehmann, R.2    Luzi, L.3    Battezzati, A.4    Angelico, M.C.5    Ricordi, C.6    Tzakis, A.7    Alejandro, R.8
  • 41
    • 1642392488 scopus 로고    scopus 로고
    • New onset diabetes mellitus after liver transplantation: The critical role of hepatitis C infection
    • Khalili M, Lim JW, Bass N, Ascher NL, Roberts JP, Terrault NA. New onset diabetes mellitus after liver transplantation: the critical role of hepatitis C infection. Liver Transpl 2004; 10: 349-355
    • (2004) Liver Transpl , vol.10 , pp. 349-355
    • Khalili, M.1    Lim, J.W.2    Bass, N.3    Ascher, N.L.4    Roberts, J.P.5    Terrault, N.A.6
  • 42
    • 2942696213 scopus 로고    scopus 로고
    • Results of lis2t, a multicenter, randomized study comparing cyclosporine microemulsion with C2 monitoring and tacrolimus with C0 monitoring in de novo liver transplantation
    • Levy G, Villamil F, Samuel D, Sanjuan F, Grazi GL, Wu Y, Marotta P, Boillot O, Muehlbacher F, Klintmalm G. Results of lis2t, a multicenter, randomized study comparing cyclosporine microemulsion with C2 monitoring and tacrolimus with C0 monitoring in de novo liver transplantation. Transplantation 2004; 77: 1632-1638
    • (2004) Transplantation , vol.77 , pp. 1632-1638
    • Levy, G.1    Villamil, F.2    Samuel, D.3    Sanjuan, F.4    Grazi, G.L.5    Wu, Y.6    Marotta, P.7    Boillot, O.8    Muehlbacher, F.9    Klintmalm, G.10
  • 43
    • 33745336579 scopus 로고    scopus 로고
    • Cyclosporin versus tacrolimus as primary immunosuppressant after liver transplantation: A metaanalysis
    • McAlister VC, Haddad E, Renouf E, Malthaner RA, Kjaer MS, Gluud LL. Cyclosporin versus tacrolimus as primary immunosuppressant after liver transplantation: a metaanalysis. Am J Transplant 2006; 6: 1578-1585
    • (2006) Am J Transplant , vol.6 , pp. 1578-1585
    • McAlister, V.C.1    Haddad, E.2    Renouf, E.3    Malthaner, R.A.4    Kjaer, M.S.5    Gluud, L.L.6
  • 44
    • 0038434537 scopus 로고    scopus 로고
    • Diabetes mellitus after liver transplant new etiologic clues and cornerstones for understanding
    • Tueche SG. Diabetes mellitus after liver transplant new etiologic clues and cornerstones for understanding. Transplant Proc 2003; 35: 1466-1468
    • (2003) Transplant Proc , vol.35 , pp. 1466-1468
    • Tueche, S.G.1
  • 45
    • 77951880020 scopus 로고    scopus 로고
    • Risk factors for new-onset diabetes mellitus in adult liver transplant recipients, an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing database
    • Kuo HT, Sampaio MS, Ye X, Reddy P, Martin P, Bunnapradist S. Risk factors for new-onset diabetes mellitus in adult liver transplant recipients, an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing database. Transplantation 2010; 89: 1134-1140
    • (2010) Transplantation , vol.89 , pp. 1134-1140
    • Kuo, H.T.1    Sampaio, M.S.2    Ye, X.3    Reddy, P.4    Martin, P.5    Bunnapradist, S.6
  • 49
    • 0036810356 scopus 로고    scopus 로고
    • Mechanisms involved in the side effects of glucocorticoids
    • Schäcke H, Döcke WD, Asadullah K. Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 2002; 96: 23-43
    • (2002) Pharmacol Ther , vol.96 , pp. 23-43
    • Schäcke, H.1    Döcke, W.D.2    Asadullah, K.3
  • 51
    • 34248652125 scopus 로고    scopus 로고
    • Tacrolimus monotherapy without steroids after liver transplantation--a prospective randomized double-blinded placebo-controlled trial
    • Moench C, Barreiros AP, Schuchmann M, Bittinger F, Thiesen J, Hommel G, Kraemer I, Otto G. Tacrolimus monotherapy without steroids after liver transplantation--a prospective randomized double-blinded placebo-controlled trial. Am J Transplant 2007; 7: 1616-1623
    • (2007) Am J Transplant , vol.7 , pp. 1616-1623
    • Moench, C.1    Barreiros, A.P.2    Schuchmann, M.3    Bittinger, F.4    Thiesen, J.5    Hommel, G.6    Kraemer, I.7    Otto, G.8
  • 56
    • 0031463441 scopus 로고    scopus 로고
    • Prednisone withdrawal 14 days after liver transplantation with mycophenolate: A prospective trial of cyclosporine and tacrolimus
    • Stegall MD, Wachs ME, Everson G, Steinberg T, Bilir B, Shrestha R, Karrer F, Kam I. Prednisone withdrawal 14 days after liver transplantation with mycophenolate: a prospective trial of cyclosporine and tacrolimus. Transplantation 1997; 64: 1755-1760
    • (1997) Transplantation , vol.64 , pp. 1755-1760
    • Stegall, M.D.1    Wachs, M.E.2    Everson, G.3    Steinberg, T.4    Bilir, B.5    Shrestha, R.6    Karrer, F.7    Kam, I.8
  • 57
    • 0031032623 scopus 로고    scopus 로고
    • Prednisone withdrawal late after adult liver transplantation reduces diabetes, hypertension, and hypercholesterolemia without causing graft loss
    • Stegall MD, Everson GT, Schroter G, Karrer F, Bilir B, Sternberg T, Shrestha R, Wachs M, Kam I. Prednisone withdrawal late after adult liver transplantation reduces diabetes, hypertension, and hypercholesterolemia without causing graft loss. Hepatology 1997; 25: 173-177
    • (1997) Hepatology , vol.25 , pp. 173-177
    • Stegall, M.D.1    Everson, G.T.2    Schroter, G.3    Karrer, F.4    Bilir, B.5    Sternberg, T.6    Shrestha, R.7    Wachs, M.8    Kam, I.9
  • 62
    • 0035960038 scopus 로고    scopus 로고
    • Posttransplant diabetes mellitus in liver transplant recipients: Risk factors, temporal relationship with hepatitis C virus allograft hepatitis, and impact on mortality
    • Baid S, Cosimi AB, Farrell ML, Schoenfeld DA, Feng S, Chung RT, Tolkoff-Rubin N, Pascual M. Posttransplant diabetes mellitus in liver transplant recipients: risk factors, temporal relationship with hepatitis C virus allograft hepatitis, and impact on mortality. Transplantation 2001; 72: 1066-1072
    • (2001) Transplantation , vol.72 , pp. 1066-1072
    • Baid, S.1    Cosimi, A.B.2    Farrell, M.L.3    Schoenfeld, D.A.4    Feng, S.5    Chung, R.T.6    Tolkoff-Rubin, N.7    Pascual, M.8
  • 65
    • 0036023929 scopus 로고    scopus 로고
    • Outcome of patients with newonset diabetes mellitus after liver transplantation compared with those without diabetes mellitus
    • John PR, Thuluvath PJ. Outcome of patients with newonset diabetes mellitus after liver transplantation compared with those without diabetes mellitus. Liver Transpl 2002; 8: 708-713
    • (2002) Liver Transpl , vol.8 , pp. 708-713
    • John, P.R.1    Thuluvath, P.J.2
  • 67
    • 77954423888 scopus 로고    scopus 로고
    • Diabetes mellitus increases the risk of mortality following liver transplantation independent of MELD score
    • Samuelson AL, Lee M, Kamal A, Keeffe EB, Ahmed A. Diabetes mellitus increases the risk of mortality following liver transplantation independent of MELD score. Dig Dis Sci 2010; 55: 2089-2094
    • (2010) Dig Dis Sci , vol.55 , pp. 2089-2094
    • Samuelson, A.L.1    Lee, M.2    Kamal, A.3    Keeffe, E.B.4    Ahmed, A.5
  • 68
    • 0036782790 scopus 로고    scopus 로고
    • Hypertensinogenic mechanism of the calcineurin inhibitors
    • Curtis JJ. Hypertensinogenic mechanism of the calcineurin inhibitors. Curr Hypertens Rep 2002; 4: 377-380
    • (2002) Curr Hypertens Rep , vol.4 , pp. 377-380
    • Curtis, J.J.1
  • 69
    • 0036270101 scopus 로고    scopus 로고
    • Immunosuppression impact on long-term cardiovascular complications after liver transplantation
    • Rabkin JM, Corless CL, Rosen HR, Olyaei AJ. Immunosuppression impact on long-term cardiovascular complications after liver transplantation. Am J Surg 2002; 183: 595-599
    • (2002) Am J Surg , vol.183 , pp. 595-599
    • Rabkin, J.M.1    Corless, C.L.2    Rosen, H.R.3    Olyaei, A.J.4
  • 73
    • 0032957129 scopus 로고    scopus 로고
    • Serum cholesterol changes in long-term survivors of liver transplantation: A comparison between cyclosporine and tacrolimus therapy
    • Charco R, Cantarell C, Vargas V, Capdevila L, Lázaro JL, Hidalgo E, Murio E, Margarit C. Serum cholesterol changes in long-term survivors of liver transplantation: a comparison between cyclosporine and tacrolimus therapy. Liver Transpl Surg 1999; 5: 204-208
    • (1999) Liver Transpl Surg , vol.5 , pp. 204-208
    • Charco, R.1    Cantarell, C.2    Vargas, V.3    Capdevila, L.4    Lázaro, J.L.5    Hidalgo, E.6    Murio, E.7    Margarit, C.8
  • 77
    • 0037623421 scopus 로고    scopus 로고
    • Ten years of sirolimus therapy in orthotopic liver transplant recipients
    • Neff GW, Montalbano M, Tzakis AG. Ten years of sirolimus therapy in orthotopic liver transplant recipients. Transplant Proc 2003; 35: 209S-216S
    • (2003) Transplant Proc , vol.35
    • Neff, G.W.1    Montalbano, M.2    Tzakis, A.G.3
  • 79
    • 0035018702 scopus 로고    scopus 로고
    • Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus
    • Trotter JF, Wachs ME, Trouillot TE, Bak T, Kugelmas M, Kam I, Everson G. Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus. Liver Transpl 2001; 7: 401-408
    • (2001) Liver Transpl , vol.7 , pp. 401-408
    • Trotter, J.F.1    Wachs, M.E.2    Trouillot, T.E.3    Bak, T.4    Kugelmas, M.5    Kam, I.6    Everson, G.7
  • 83
    • 0035082875 scopus 로고    scopus 로고
    • Physical activity and health-related quality of life in liver transplant recipients
    • Painter P, Krasnoff J, Paul SM, Ascher NL. Physical activity and health-related quality of life in liver transplant recipients. Liver Transpl 2001; 7: 213-219
    • (2001) Liver Transpl , vol.7 , pp. 213-219
    • Painter, P.1    Krasnoff, J.2    Paul, S.M.3    Ascher, N.L.4
  • 84
    • 0033040097 scopus 로고    scopus 로고
    • Liver transplantation, body composition, and substrate utilization: Does organ transplantation normalize the metabolic situation of the patient?
    • Roske AE, Plauth M. Liver transplantation, body composition, and substrate utilization: does organ transplantation normalize the metabolic situation of the patient? Nutrition 1999; 15: 504-505
    • (1999) Nutrition , vol.15 , pp. 504-505
    • Roske, A.E.1    Plauth, M.2
  • 87
    • 56549097541 scopus 로고    scopus 로고
    • Adjustable gastric banding in a morbidly obese patient during liver transplantation
    • Campsen J, Zimmerman M, Shoen J, Wachs M, Bak T, Mandell MS, Kam I. Adjustable gastric banding in a morbidly obese patient during liver transplantation. Obes Surg 2008; 18: 1625-1627
    • (2008) Obes Surg , vol.18 , pp. 1625-1627
    • Campsen, J.1    Zimmerman, M.2    Shoen, J.3    Wachs, M.4    Bak, T.5    Mandell, M.S.6    Kam, I.7
  • 88
    • 84864439248 scopus 로고    scopus 로고
    • Elevated Serum Creatinine and the Metabolic Syndrome are Associated with Major Vascular Events After Liver Transplantation
    • Kallwitz ER, TenCate V, Mettu PS, Koyhnw N, Berkes JL, Layden TJ, Cotler SJ. Elevated Serum Creatinine and the Metabolic Syndrome are Associated with Major Vascular Events After Liver Transplantation. Hepatology 2011; 54: A574
    • (2011) Hepatology , vol.54
    • Kallwitz, E.R.1    TenCate, V.2    Mettu, P.S.3    Koyhnw, N.4    Berkes, J.L.5    Layden, T.J.6    Cotler, S.J.7


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