Prednisone withdrawal 14 days after liver transplantation with mycophenolate: A prospective trial of cyclosporine and tacrolimus

Transplantation

Volumn 64, Issue 12, 1997, Pages 1755-1760

  Stegall, Mark D ^a   Wachs, Michael E ^a   Everson, Gregory ^a   Steinberg, Tracy ^a   Bilir, Bahri ^a   Shrestha, Roshan ^a   Karrer, Frederick ^a   Kam, Igal ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYCLOSPORIN; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

ADULT; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; GINGIVITIS; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; INTRAGASTRIC DRUG ADMINISTRATION; LEUKOPENIA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; NEUROTOXICITY; ORAL DRUG ADMINISTRATION; PHASE 2 CLINICAL TRIAL; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SEIZURE; THROMBOCYTOPENIA;

ACUTE DISEASE; ADULT; CYCLOSPORINE; DIABETES MELLITUS; DRUG ADMINISTRATION SCHEDULE; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; HYPERTENSION; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; LIVER; LIVER TRANSPLANTATION; MYCOPHENOLIC ACID; PREDNISONE; PROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TACROLIMUS; TIME FACTORS;

EID: 0031463441     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199712270-00023     Document Type: Conference Paper

References (17)

1. Stegall MD, Everson G, Schroter G, et al. Metabolic complications after liver transplantation: diabetes, hypercholesterolemia and obesity. Transplantation 1995; 60: 1057.
2. Higgins RM, Ratcliffe PJ. Hypercholesterolemia and vascular disease after transplantation. Transplant Rev 1991; 5: 131.
3. Levy MF, Goldstein RM, Husberg, et al. Baylor update: outcome analysis in liver transplantation. In: Terasaki P, Cecka J, eds. Clinical transplants 1993. Los Angeles: UCLA Tissue Typing Laboratory, 1994: 161.
4. European Mycophenolate Mofetil Cooperative Study Group. Placebo-controlled study of mycophenolate mofetil (MMF). Lancet 195; 345: 1321.
5. Sollinger HW for the U.S. Renal Transplant Mycophenolate Study Group. Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. Transplantation 1995; 60: 225.
6. Tricontinental Mycophenolate Mofetil Renal Transplant Study Group. A blinded, randomized clinical trial of mycophenolate for the prevention of acute rejection in cadaveric renal transplantation. Transplantation 1996; 61: 1029.
7. Halloran P, Hathew T, Tomlanovich S, et al. Mycophenolate mofetil in renal allograft recipients: a pooled efficacy analysis of three randomized, double-blind, clinical studies in prevention of rejection. Transplantation 1997; 63: 39.
8. Klintmalm G, Ascher N, Busuttil R, et al. RS61443 for treatment-resistant human liver rejection. Transplant Proc 1993; 25: 697.
9. Gavlik A, Goldberg MG, Tsaroucha A, et al. Mycophenolate mofetil rescue therapy in liver transplant recipients. Transplant Proc 1997; 29: 549.
10. European FK506 Multicentre Liver Study Group: Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejection. Lancet 1994; 344: 423.
11. The US Multicenter FK506 Liver Study Group: A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression in liver transplantation. N Engl J Med 1994; 331: 1110.
12. Busuttil RW, Holt CD. Tacrolimus (FK506) is superior to cyclosporine in liver transplantation. Transplant Proc 1997; 29: 534.
13. Stegall MD, Everson GT, Schroter G, et al. Prednisone withdrawal late after adult liver transplantation reduces diabetes, hypertension and hypercholesterolemia without causing graft loss. Hepatology 1997; 25: 173.
14. De Carlis L, Belli LS, Rondinara GF, et al. Early steroid withdrawal in liver transplant patients: final report of a prospective randomized trial. Transplant Proc 1997; 29: 539.
15. Padbury RTA, Gunson BK, Doussett B, et al. Steroid withdrawal from long-term immunosuppression in liver allograft recipients. Transplantation 1993; 55: 789.
16. Andrews WS, Shimoaka S, Sommerauer J, et al. Steroid withdrawal after pediatric liver transplantation. Transplant Proc 1994; 26: 159.
17. McDiarmid SV, Farmer D, Goldstein LI, et al. A randomized, prospective trial of steroid withdrawal after liver transplantation. Transplantation 1995; 60: 1443.