Towards MR-navigable nanorobotic carriers for drug delivery into the brain

Proceedings - IEEE International Conference on Robotics and Automation

Volumn , Issue , 2012, Pages 727-732

  Tabatabaei, Seyed Nasrollah ^a   Duchemin, Sonia ^b   Girouard, Helene ^b   Martel, Sylvain ^a  

^a ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; MAGNETIC FIELDS; MAGNETIC RESONANCE IMAGING; NANOMAGNETICS; NANOPARTICLES; PROPULSION; ROBOTS; SATURATION MAGNETIZATION; TARGETED DRUG DELIVERY;

ALTERNATING MAGNETIC FIELD; BLOOD-BRAIN BARRIER; BRAIN DRUG DELIVERIES; HISTOLOGICAL OBSERVATIONS; HOMOGENEOUS MAGNETIC FIELD; MAGNETIC NANOPARTI CLES (MNPS); MAGNETIC RESONANCE IMAGING (MRI); MAGNETIZATION-SATURATION;

CONTROLLED DRUG DELIVERY;

EID: 84864437968     PISSN: 10504729     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ICRA.2012.6225041     Document Type: Conference Paper

References (33)

1. W. M. Pardridge, "Blood-brain barrier drug targeting: the future of brain drug development," Molecular Interventions, vol. 3, pp. 90-105, March 1, 2003 2003.
2. P. Pouponneau, J.-C. Leroux, and S. Martel, "Magnetic nanoparticles encapsulated into biodegradable microparticles steered with an upgraded magnetic resonance imaging system for tumor chemoembolization," Biomaterials, vol. 30, pp. 6327-6332, 2009.
3. P. Pouponneau, J.-C. Leroux, G. Soulez, L. Gaboury, and S. Martel, "Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation," Biomaterials, vol. In Press, Corrected Proof, 2011.
4. E. Moriyama, M. Salcman, and R. D. Broadwell, "Blood-brain barrier alteration after microwave-induced hyperthermia is purely a thermal effect: I. Temperature and power measurements," Surgical Neurology, vol. 35, pp. 177-182, 1991.
5. H. S. Sharma, J. A. Duncan, and C. E. Johanson, "Whole-body hyperthermia in the rat disrupts the blood-cerebrospinal fluid barrier and induces brain edema," in Brain Edema XIII. vol. 96, J. T. Hoff, R. F. Keep, G. Xi, and Y. Hua, Eds., ed: Springer Vienna, 2006, pp. 426-431.
6. J. C. Lin, P. M. K. Yuan, and D. T. Jung, "Enhancement of anticancer drug delivery to the brain by microwave induced hyperthermia," Bioelectrochemistry and Bioenergetics, vol. 47, pp. 259-264, 1998.
7. H. Masuda, A. Hirata, H. Kawai, K. Wake, S. Watanabe, T. Arima, F. Poulletier de Gannes, I. Lagroye, and B. Veyret, "Local exposure of the rat cortex to radiofrequency electromagnetic fields increases local cerebral blood flow along with temperature," Journal of Applied Physiology, vol. 110, pp. 142-148, 2011.
8. P. Wust, B. Hildebrandt, G. Sreenivasa, B. Rau, J. Gellermann, H. Riess, R. Felix, and P. M. Schlag, "Hyperthermia in combined treatment of cancer," The Lancet Oncology, vol. 3, pp. 487-497, 2002.
9. Q. A. Pankhurst, J. Connolly, S. K. Jones, and J. Dobson, "Applications of magnetic nanoparticles in biomedicine," Journal of Physics D: Applied Physics, vol. 36, pp. R167-R181, 2003.
10. E. R. Kandel, J. H. Schwartz, and T. M. Jessell, Principles of Neural Science, 4th ed.: McGraw-Hill, 2000.
11. H. Fischer, R. Gottschlich, and A. Seelig, "Blood-Brain Barrier Permeation: Molecular Parameters Governing Passive Diffusion," Journal of Membrane Biology, vol. 165, pp. 201-211, 1998.
12. A. BÈduneau, P. Saulnier, and J.-P. Benoit, "Active targeting of brain tumors using nanocarriers," Biomaterials, vol. 28, pp. 4947-4967, 2007.
13. W. M. Pardridge, Brain drug targeting. United Kingdom: Cambridge University Press, 2001.
14. W. M. Pardridge, "Drug and gene targeting to the brain via blood-brain barrier receptor-mediated transport systems," International Congress Series, vol. 1277, pp. 49-62, 2005.
15. N. J. Abbott, L. Ronnback, and E. Hansson, "Astrocyte-endothelial interactions at the blood-brain barrier," Nat Rev Neurosci, vol. 7, pp. 41-53, 2006.
16. K. E. Schlageter, P. Molnar, G. D. Lapin, and D. R. Groothuis, "Microvessel Organization and Structure in Experimental Brain Tumors: Microvessel Populations with Distinctive Structural and Functional Properties," Microvascular Research, vol. 58, pp. 312-328, 1999.
17. Josef Friedl, Ewa Turner, and H. R. Alexander, "Augmentation of endothelial cell monolayer permeability by hyperthermia but not tumor necrosis factor: Evidence for disruption of vascular integrity via VE-cadherin down-regulation," International Journal of Oncology, vol. 23, pp. 611-616, 2003.
18. V. V. Jeliazkova-Mecheva, W. C. Hymer, N. C. Nicholas, and D. J. Bobilya, "Brief heat shock affects the permeability and thermotolerance of an in vitro blood-brain barrier model of porcine brain microvascular endothelial cells," Microvascular Research, vol. 71, pp. 108-114, 2006.
19. L. v. Michael and et al., "Magnetically induced hyperthermia: size-dependent heating power of $-Fe 2 O 3 nanoparticles," Journal of Physics: Condensed Matter, vol. 20, p. 204133, 2008.
20. R. Hergt and S. Dutz, "Magnetic particle hyperthermia - biophysical limitations of a visionary tumour therapy," Journal of Magnetism and Magnetic Materials, vol. 311, pp. 187-192, 2007.
21. W. H. Suh, K. S. Suslick, G. D. Stucky, and Y.-H. Suh, "Nanotechnology, nanotoxicology, and neuroscience," Progress in Neurobiology, vol. 87, pp. 133-170, 2009.
22. S. N. Tabatabaei, J. Lapointe, and S. Martel, "Shrinkable Hydrogel- Based Magnetic Microrobots for Interventions in the Vascular Network," Advanced Robotics, vol. 25, pp. 1049-1067, 2011.
23. S. N. Tabatabaei, "Evaluation of hyperthermia using magnetic nanoparticles and alternating magnetic field," Master, Institute of Biomedical Engineering, University of Montreal, Montreal, 2010.
24. J.-H. Lee, J.-t. Jang, J.-s. Choi, S. H. Moon, S.-h. Noh, J.-w. Kim, J.-G. Kim, I.-S. Kim, K. I. Park, and J. Cheon, "Exchange-coupled magnetic nanoparticles for efficient heat induction," Nat Nano, vol. 6, pp. 418-422, 2011.
25. O. Pillai and R. Panchagnula, "Polymers in drug delivery," Current Opinion in Chemical Biology, vol. 5, pp. 447-451, 2001.
26. D. Jiles, Introduction to magnetism and magnetic materials, 1st ed. New York: Chapman and Hall, 1990.
27. C. Alexiou, W. Arnold, R. J. Klein, F. G. Parak, P. Hulin, C. Bergemann, W. Erhardt, S. Wagenpfeil, and A. S. L√°bbe, "Locoregional Cancer Treatment with Magnetic Drug Targeting," Cancer Research, vol. 60, pp. 6641-6648, December 1, 2000 2000.
28. S. Martel, O. Felfoul, J.-B. Mathieu, A. Chanu, S. Tamaz, M. Mohammadi, M. Mankiewicz, and N. Tabatabaei, "MRI-based Medical Nanorobotic Platform for the Control of Magnetic Nanoparticles and Flagellated Bacteria for Target Interventions in Human Capillaries," The International Journal of Robotics Research, vol. 28, pp. 1169-1182, September 1, 2009 2009.
29. J. Lin and M. Lin, "Microwave hyperthermia-induced blood-brain barrier alterations," Radiation Research, vol. 89, pp. 77-87, 1982.
30. E. A. Kiyatkin and H. S. Sharma, "Permeability of the blood-brain barrier depends on brain temperature," Neuroscience, vol. 161, pp. 926-939, 2009.
31. J. Hed, C. Dahlgren, and I. Rundquist, "A simple fluorescence technique to stain the plasma membrane of human neutrophils," Histochemistry and Cell Biology, vol. 79, pp. 105-110, 1983.
32. E. Duguet, L. Hardel, and S. Vasseur, "Cell Targeting and Magnetically Induced Hyperthermia," in Thermal Nanosystems and Nanomaterials. vol. 118, S. Volz, Ed., ed: Springer Berlin / Heidelberg, 2009, pp. 343-365.
33. S. M. Moghimi, A. C. Hunter, and J. C. Murray, "Long-Circulating and Target-Specific Nanoparticles: Theory to Practice," Pharmacological Reviews, vol. 53, pp. 283-318, June 1, 2001 2001.