1,25(OH)2D3 inhibits the deleterious effects induced by high glucose on osteoblasts through undercarboxylated osteocalcin and insulin signaling

Journal of Steroid Biochemistry and Molecular Biology

Volumn 132, Issue 1-2, 2012, Pages 112-119

  Wu, Ying Ying ^a,b   Yu, Tao ^b,c   Zhang, Xiao Hui ^a,b   Liu, Yan Shan ^a,b   Li, Feng ^a,b   Wang, Yan Ying ^a,b   Wang, Yong Yue ^a,b   Gong, Ping ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

1,25(OH)2D3; Diabetes mellitus; Insulin; Osteoblast; Undercarboxylated osteocalcin

Indexed keywords

1,25 DIHYDROXYERGOCALCIFEROL; ALKALINE PHOSPHATASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; MESSENGER RNA; OSTEOCALCIN; VITAMIN D RECEPTOR;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSPOT ASSAY; IN VITRO STUDY; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANIMALS; CALCITRIOL; CELL PROLIFERATION; CELLS, CULTURED; GLUCOSE; INSULIN; OSTEOBLASTS; OSTEOCALCIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; RECEPTORS, CALCITRIOL; RNA, MESSENGER;

RATTUS;

EID: 84864437833     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.05.002     Document Type: Article

References (33)

1. P.T. Kumar, S. Antony, M.S. Nandhu, J. Sadanandan, G. Naijil, and C.S. Paulose Vitamin D3 restores altered cholinergic and insulin receptor expression in the cerebral cortex and muscarinic M3 receptor expression in pancreatic islets of streptozotocin induced diabetic rats The Journal of Nutritional Biochemistry 22 2011 418 425
2. M. Gerritsen, J.A. Lutterman, and J.A. Jansen Wound healing around boneanchored percutaneous devices in experimental diabetes mellitus Journal of Biomedical Materials Research 53 2000 702 709
3. E. Balint, P. Szabo, C.F. Marshall, and S.M. Sprague Glucose-induced inhibition of in vitro bone mineralization Bone 28 2001 21 28 (Pubitemid 32114089)
4. D. Zhen, Y. Chen, and X. Tang Metformin reverses the deleterious effects of high glucose on osteoblast function Journal of Diabetes and its Complications 24 2010 334 344
5. M. Terada, M. Inaba, Y. Yano, T. Hasuma, Y. Nishizawa, H. Morii, and S. Otani Growth-inhibitory effect of a high glucose concentration on osteoblast-like cells Bone 22 1998 17 23 (Pubitemid 28033648)
6. K. Fulzele, R.C. Riddle, D.J. DiGirolamo, X. Cao, C. Wan, D. Chen, M.C. Faugere, S. Aja, M.A. Hussain, J.C. Brüning, and T.L. Clemens Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition Cell 142 2010 309 319
7. M. Kasuga, Y. Fujita-Yamaguchi, D.L. Blithe, M.F. White, and C.R. Kahn Characterization of the insulin receptor kinase purified from human placental membranes Journal of Biological Chemistry 258 1983 10973 10980 (Pubitemid 13021262)
8. Z. Zhang, and Z. Zhang Comment on Vitamin D deficiency is the cause of common obesity Medical Hypotheses 73 2009 123
9. M. McCart Poor vitamin D status may contribute to high risk for insulin resistance, obesity, and cardiovascular disease in Asian Indians Medical Hypotheses 72 2009 647 651
10. B.M. Misof, P. Roschger, W. Tesch, P.A. Baldock, A. Valenta, P. Messmer, J.A. Eisman, A.L. Boskey, E.M. Gardiner, P. Fratzi, and K. Klaushofer Targeted overexpression of Vitamin D receptor in osteoblasts increases calcium concentration without affecting structural properties of bone mineral crystals Calcified Tissue International 73 2003 251 257 (Pubitemid 37152886)
11. B. Maestro, S. Molero, S. Bajo, N. Dávila, and C. Calle Transcriptional activation of the human insulin receptor gene by 1,25-dihydroxyvitamin D3 Cell Biochemistry and Function 20 2002 227 232
12. B. Maestro, J. Campión, N. Dávila, and C. Calle Stimulation by 1,25-dihydroxyvitamin D3 of insulin receptor expression and insulin responsiveness for glucose transport in U-937 human promonocytic cells Endocrine Journal 47 2000 383 391
13. U. Zeitz, K. Weber, D.W. Soegiarto, E. Wolf, R. Balling, and R.G. Erben Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor FASEB Journal 17 2003 509 511
14. H.A. Bischoff, M. Borchers, F. Gudat, U. Duermueller, R. Thheiler, H.B. Stähelin, and W. Dick In situ detection of 1,25-dihydroxyvitamin D3 receptor in human skeletal muscle tissue Histochemical Journal 33 2001 19 24 (Pubitemid 32368054)
15. A.W. Norman Minireview: vitamin D receptor: new assignments for an already busy receptor Endocrinology 147 2006 5542 5548 (Pubitemid 44833469)
16. J.A. Alvarez, and A. Ashraf Role of vitamin D in insulin secretion and insulin sensitivity for glucose homeostasis International Journal of Endocrinology 35 2010 1385
17. M. Yamauchi, T. Yamaguchi, K. Nawata, S. Takaoka, and T. Sugimoto Relationships between undercarboxylated osteocalcin and vitamin K intakes, bone turnover, and bone mineral density in healthy women Clinical Nutrition 29 2010 761 765
18. M.S. Fewtrell, C. Benden, J.E. Williams, S. Chomtho, F. Ginty, S.V. Nigdikar, and A. Jaffe Undercarboxylated osteocalcin and bone mass in 8-12 year old children with cystic fibrosis Journal of Cystic Fibrosis 7 2008 307 312
19. M. Ferron, J. Wei, T. Yoshizawa, A. Del Fattore, R.A. DePinho, A. Teti, P. Ducy, and G. Karsenty Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism Cell 142 2010 296 308
20. E. Hinoi, N. Gao, D.Y. Jung, V. Yadav, T. Yoshizawa, M.G. Myers Jr., S.C. Chua Jr., J.K. Kim, K.H. Kaestner, and G. Karsenty The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity The Journal of Cell Biology 183 2008 1235 1242
21. N.K. Lee, H. Sowa, E. Hinoi, M. Ferron, J.D. Ahn, C. Confavreux, R. Dacquin, P.J. Mee, M.D. Mckee, D.Y. Jung, Z. Zhang, J.K. Kim, F. Mauvais-Jarvis, P. Ducy, and G. Karsenty Endocrine regulation of energy metabolism by the skeleton Cell 130 2007 456 469 (Pubitemid 47208519)
22. D. Masquelier, B. Herbert, N. Hauser, P. Mermillod, E. Schonne, and C. Remacle Morphologic characterization of osteoblast-like cell cultures isolated from newborn rat calvaria Calcified Tissue International 47 1990 92 104 (Pubitemid 20238173)
23. S. Varghese, N. Wyzga, A.M. Griffiths, and F.A. Sylvester Effects of serum from children with newly diagnosed Crohn disease on primary cultures of rat osteoblasts Journal of Pediatric Gastroenterology and Nutrition 35 2002 641 648 (Pubitemid 35417735)
24. S.L. Wang, N. Liu, S.Y. Yang, H. Wu, and Z.G. Zha Culture and identification of SD rat osteoblastsby modified enzymatic digestion in vitro Journal of Clinical Rehabilitative Tissue Engineering Research 12 2008 2983 2987 (Pubitemid 351864547)
25. G. Liu, and M. Peacock Age-related changes in serum undercarboxylated osteocalcin and its relationships with bone density, bone quality, and hip fracture Calcified Tissue International 62 1998 286 289 (Pubitemid 28139308)
26. H. Streeck, N. Frahm, and B.D. Walker The role of IFN-gamma Elispot assay in HIV vaccine research Nature Protocols 4 2009 461 469
27. M. Blüher, M.D. Michael, O.D. Peroni, K. Ueki, N. Carter, B.B. Kahn, and C.R. Kahn Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance Developmental Cell 3 2002 25 38 (Pubitemid 34778393)
28. R.N. Kulkarni, J.C. Brüning, J.N. Winnay, C. Postic, M.A. Magnuson, and C.R. Kahn Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes Cell 96 1999 329 339 (Pubitemid 29077587)
29. M.D. Michael, R.N. Kulkarni, C. Postic, S.F. Previs, G.I. Shulman, M.A. Magnuson, and C.R. Kahn Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction Molecular Cell 6 2000 87 97
30. A.W. Norman, J.B. Frankel, A.M. Heldt, and G.M. Grodsky Vitamin D deficiency inhibits pancreatic secretion of insulin Science 209 1980 823 825 (Pubitemid 10017495)
31. C. Cade, and A.N. Norman Vitamin D3 improves impaired glucose tolerance and insulin secretion in the vitamin D-deficient rat in vivo Endocrinology 119 1986 84 90 (Pubitemid 16100711)
32. H. Kaji, I. Hisa, Y. Inoue, J. Naito, T. Sugimoto, and M. Kasuga Analysis of factors affecting increase in bone mineral density at lumbar spine by bisphosphonate treatment in postmenopausal osteoporosis Journal of Bone and Mineral Metabolism 27 2009 76 82
33. P. Lips Vitamin D physiology Progress in Biophysics and Molecular Biology 92 2006 4 8 (Pubitemid 43831956)