Suppression of Akt/Foxp3-mediated miR-183 expression blocks Sp1-mediated ADAM17 expression and TNFα-mediated NFκB activation in piceatannol-treated human leukemia U937 cells

Biochemical Pharmacology

Volumn 84, Issue 5, 2012, Pages 670-680

  Liu, Wen Hsin ^a   Chang, Long Sen ^a,b  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

TrCP; Foxp3; miR 183; Piceatannol; Sp1; TNF

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 183; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PICEATANNOL; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE INACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

ADAM PROTEINS; BASE SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; LEUKEMIA; MICRORNAS; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SP1 TRANSCRIPTION FACTOR; STILBENES; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 84864418149     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.06.007     Document Type: Article

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