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Volumn 54, Issue , 2012, Pages 87-94

Synthesis and biological evaluation of 4-alkoxy-6,9-dichloro[1,2,4] triazolo[4,3-a]quinoxalines as inhibitors of TNF-α and IL-6

(5) Guirado, Antonio a López Sánchez, José I a Ruiz Alcaraz, Antonio J a Bautista, Delia a Gálvez, Jesús a

a UNIVERSITY OF MURCIA (Spain)

Author keywords

Anti inflammatory activity; IL 6; TNF ; Triazoloquinoxalines

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (SEC BUTOXY) 6,9 DICHLORO[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 4 BENZYLOXY 6,9 DICHLORO[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 6,9 DICHLORO 4 (3 METHYLBENZYLOXY)[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 6,9 DICHLORO 4 (4 FLUOROBENZYLOXY)[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 6,9 DICHLORO 4 (4 METHOXYBENZYLOXY)[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 6,9 DICHLORO 4 ETHOXY[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 6,9 DICHLORO 4 ISOPROPOXY[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; 6,9 DICHLORO 4 METHOXY[1,2,4]TRIAZOLO[4,3 A]QUINOXALINE; INTERLEUKIN 6; QUINOXALINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CHEMISTRY TECHNIQUES, SYNTHETIC; HL-60 CELLS; HUMANS; INTERLEUKIN-6; QUINOXALINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864417273 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.04.035 Document Type: Article

Times cited : (44)

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