New N-arylamino biquinoline derivatives: Synthesis, antimicrobial, antituberculosis, and antimalarial evaluation

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 239-247

  Shah, Nimesh M ^a   Patel, Manish P ^a   Patel, Ranjan G ^a  

^a SARDAR PATEL UNIVERSITY   (India)

Author keywords

Antimicrobial activity; IC50; Multicomponent reaction; Quinoline

Indexed keywords

2 AMINO 4 [2 CHLORO (3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 FLUOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO (3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 METHYLPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHOXY(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 CHLOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHOXY(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 FLUOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHOXY(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 METHYLPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHOXY(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 PHENYLAMINO 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHYL(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 CHLOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHYL(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 FLUOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHYL(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 METHYLPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO 6 METHYL(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 PHENYLAMINO 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 METHOXYPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 CHLORO(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 PHENYLAMINO 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2 DICHLORO(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 METHYLPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2,6 DICHLORO (3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 CHLOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2,6 DICHLORO (3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 PHENYLAMINO 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 AMINO 4 [2,6 DICHLORO(3 QUINOLYL)] 7,7 DIMETHYL 5 OXO 1 (4 FLUOROPHENYLAMINO) 1,4,6,7,8 PENTAHYDRO QUINOLINE 3 CARBONITRILE; 2 CHLORO 3 FORMYLQUINOLINE DERIVATIVE; ALCOHOL; AMPICILLIN; ANTIBIOTIC AGENT; CHLORAMPHENICOL; CIPROFLOXACIN; ENHYDRAZINOKETONE DERIVATIVE; GRISEOFULVIN; KETONE DERIVATIVE; MALONONITRILE; N ARYLAMINO BIQUINOLINE DERIVATIVE; NORFLOXACIN; NYSTATIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYSICAL CHEMISTRY; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; ANTITUBERCULAR AGENTS; CHEMISTRY TECHNIQUES, SYNTHETIC; ELECTRONS; FUNGI; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM FALCIPARUM; QUINOLINES;

EID: 84864413116     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.05.004     Document Type: Article

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