Growth-inhibitory and apoptosis-inducing effects of tanshinones on hematological malignancy cells and their structure-activity relationship

Anti-Cancer Drugs

Volumn 23, Issue 8, 2012, Pages 846-855

  Li, Hui ^a,c   Zhang, Qing ^b   Chu, Ting ^b   Shi, Hua Yue ^b   Fu, Hui Min ^b   Song, Xiang Rong ^a   Meng, Wen Tong ^a   Mao, Sheng Jun ^b   Jia, Yong Qian ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

antitumor drug; apoptosis; hematological malignancy; structure activity relationship; tanshinones

Indexed keywords

ANTINEOPLASTIC AGENT; CRYPTOTANSHINONE; DIHYDROTANSHINONE; TANSHINONE I; TANSHINONE IIA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN K 562; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; IC 50; PHASE CONTRAST MICROSCOPE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BURKITT LYMPHOMA; CELL LINE, TUMOR; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MICROSCOPY, FLUORESCENCE; PHENANTHRENES; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84864409256     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e328351f896     Document Type: Article

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