Regioselective reaction: Synthesis, characterization and pharmacological activity of some new Mannich and Schiff bases containing sydnone

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 597-604

  Nithinchandra, ^a   Kalluraya, B ^a   Aamir, S ^b   Shabaraya, A R ^b  

^a MANGALORE UNIVERSITY   (India)

^b SRINIVAS COLLEGE OF PHARMACY   (India)

Author keywords

1,2,4 Triazole; Analgesic agents; Anti inflammatory agents; Mannich bases; Schiff bases; Sydnone

Indexed keywords

1 MORPHOLINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 (3 PHENYL 4 SYDNONYLIDENE)AMINO 1,2,4 TRIAZOL 5 THIONE; 1 MORPHOLINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 ANISYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 1 MORPHOLINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 TOLYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 1 N ETHYL PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 (3 PHENYL 4 SYDNONYLIDENE)AMINO 1,2,4 TRIAZOL 5 THIONE; 1 N METHYL PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 (3 PHENYL 4 SYDNONYLIDENE)AMINO 1,2,4 TRIAZOL 5 THIONE; 1 N METHYL PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 ANISYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 1 N PHENYL PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 (3 PHENYL 4 SYDNONYLIDENE)AMINO 1,2,4 TRIAZOL 5 THIONE; 1 N PHENYL PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 TOLYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 1 N PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 TOLYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 1 PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 (3 PHENYL 4 SYDNONYLIDENE)AMINO 1,2,4 TRIAZOL 5 THIONE; 1 PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 ANISYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 1 PIPERIDINOMETHYL 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [(4 TOLYL) 4 SYDNONYLIDENE]AMINO 1,2,4 TRIAZOL 5 THIONE; 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 (3 PHENYL 4 SYDNONYLIDENE)AMINO 5 MERCAPTO 1,2,4 TRIAZOLE; 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [3 (4 ANISYL) 4 SYDNONYLIDENE]AMINO 5 MERCAPTO 1,2,4 TRIAZOLE; 3 [1 (4 ISOBUTYLPHENYL)ETHYL] 4 [3 (4 TOLYL) 4 SYDNONYLIDENE]AMINO 5 MERCAPTO 1,2,4 TRIAZOLE; ANALGESIC AGENT; FORMALDEHYDE; INDOMETACIN; MANNICH BASE; PENTAZOCINE; SCHIFF BASE; SYDNONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; INFRARED SPECTROMETRY; METHYLATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CHEMISTRY TECHNIQUES, SYNTHETIC; FEMALE; MALE; MANNICH BASES; RATS; RATS, WISTAR; SCHIFF BASES; STEREOISOMERISM; SUBSTRATE SPECIFICITY; SYDNONES;

EID: 84864405447     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.06.011     Document Type: Article

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