Do premenopausal women with major depression have low bone mineral density? A 36-month prospective study

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Cizza, Giovanni ^a   Mistry, Sima ^b   Nguyen, Vi T ^a   Eskandari, Farideh ^a   Martinez, Pedro ^c   Torvik, Sara ^a   Reynolds, James C ^d   Gold, Philip W ^c   Sinai, Ninet ^d   Csako, Gyorgy ^d  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; ALENDRONIC ACID; ALKALINE PHOSPHATASE BONE ISOENZYME; AMINO TERMINAL TELOPEPTIDE; CALCIUM ION; CORTICOTROPIN; HYDROCORTISONE; OSTEOCALCIN; PARATHYROID HORMONE; PLACEBO;

ADULT; ANXIETY; ARTICLE; BONE DENSITY; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DISEASE SEVERITY; FEMALE; FEMUR NECK; HIP; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; LUMBAR SPINE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; OSTEOPOROSIS; PREMENOPAUSE; PROSPECTIVE STUDY; RADIUS; RANDOMIZED CONTROLLED TRIAL;

ADRENOCORTICOTROPIC HORMONE; ADULT; BONE DENSITY; CALCIUM; COLLAGEN TYPE I; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; HYDROCORTISONE; MIDDLE AGED; OSTEOCALCIN; OSTEOPOROSIS; PARATHYROID HORMONE; PEPTIDES; PROSPECTIVE STUDIES; VITAMIN D;

EID: 84864402787     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040894     Document Type: Article

References (64)

1. World Health Organization (2008) The global burden of disease: 2004 update Geneva World Health Organization ISBN 92 4 156257 9.
2. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, et al. (2003) The epidemiology of major depressive disorder: results from the national comorbidity survey replication (NCS-R). JAMA 289: 3095-3105.
3. Stewart WF, Ricci JA, Chee E, Hahn SR, Morganstein D, (2003) Cost of lost productive work time among US workers with depression. JAMA 289: 3135-3144.
4. Licinio J, Wong ML, (1999) The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection. Mol Psychiatry 4: 317-327.
5. Barth J, Schumacher M, Herrmann-Lingen C, (2004) Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis. Psychosom Med 66: 802-813.
6. Lett HS, Blumenthal JA, Babyak MA, Sherwood A, Strauman T, et al. (2004) Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment. Psychosom Med 66: 305-315.
7. Whang W, Kubzansky LD, Kawachi I, Rexrode KM, Kroenke CH, et al. (2009) Depression and risk of sudden cardiac death and coronary heart disease in women: results from the Nurses' Health Study. J Am Coll Cardiol 53: 950-958.
8. Rubinow DR, Girdler S, (2011) Hormones, heart disease, and health: individualized medicine versus throwing the baby out with the bathwater. Depress Anxiety 28: E1-E15.
9. Alesci S, Martinez PE, Kelkar S, Ilias I, Ronsaville DS, et al. (2005) Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications. J Clin Endocrinol Metab 90: 2522-2530.
10. Anisman H, Merali Z, Hayley S, (2008) Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders. Prog Neurobiol 85: 1-74.
11. Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW, (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9: 46-56.
12. Blume J, Douglas SD, Evans DL, (2011) Immune suppression and immune activation in depression. Brain Behav Immun 25: 221-229.
13. Brown ES, Varghese FP, McEwen BS, (2004) Association of depression with medical illness: does cortisol play a role? Biol Psychiatry 55: 1-9.
14. Timonen M, Laakso M, Jokelainen J, Rajala U, Meyer-Rochow VB, et al. (2005) Insulin resistance and depression: cross sectional study. BMJ 330: 17-18.
15. Adriaanse MC, Dekker JM, Nijpels G, Heine RJ, Snoek FJ, et al. (2006) Associations between depressive symptoms and insulin resistance: the Hoorn Study. Diabetologia 49: 2874-2877.
16. Skilton MR, Moulin P, Terra JL, Bonnet F, (2007) Associations between anxiety, depression, and the metabolic syndrome. Biol Psychiatry 62: 1251-1257.
17. Everson-Rose SA, Meyer PM, Powell LH, Pandey D, Torréns JI, et al. (2004) Depressive symptoms, insulin resistance, and risk of diabetes in women at midlife. Diabetes Care 27: 2856-2862.
18. Mezuk B, Eaton WW, Albrecht S, Golden SH, (2008) Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care 31: 2383-90.
19. Golden SH, Lazo M, Carnethon M, Bertoni AG, Schreiner PJ, et al. (2008) Examining a bidirectional association between depressive symptoms and diabetes. JAMA 299: 2751-2759.
20. Pan A, Lucas M, Sun Q, van Dam RM, Franco OH, et al. (2010) Bidirectional association between depression and type 2 diabetes mellitus in women. Arch Intern Med 170: 1884-1891.
21. Onyike CI, Crum RM, Lee HB, Lyketsos CG, Eaton WW, (2003) Is obesity associated with major depression? results from the Third National Health and Nutrition Examination Survey. Am J Epidemiol 158: 1139-1147.
22. Blaine B, (2008) Does depression cause obesity? A meta-analysis of longitudinal studies of depression and weight control. J Health Psychol 13: 1190-1197.
23. Simon GE, Ludman EJ, Linde JA, Operskalski BH, Ichikawa L, et al. (2008) Association between obesity and depression in middle-aged women. Gen Hosp Psychiatry 30: 32-39.
24. Allison DB, Newcomer JW, Dunn AL, Blumenthal JA, Fabricatore AN, et al. (2009) Obesity among those with mental disorders: a National Institute of Mental Health meeting report. Am J Prev Med 36: 341-350.
25. Amsterdam J, Hooper M, (1998) Bone density measurement in major depression. Prog Neuropsychopharmacol Biol Psychiatry 22: 267-277.
26. Cizza G, Ravn P, Chrousos GP, Gold PW, (2001) Depression: a major, unrecognized risk factor for osteoporosis? Trends Endocrinol Metab 12: 198-203.
27. Eskandari F, Martinez PE, Torvik S, Phillips TM, Sternberg EM, et al. (2007) Low bone mass in premenopausal women with depression. Arch Intern Med 167: 2329-2336.
28. Cizza G, Primma S, Csako G, (2009) Depression as a risk factor for osteoporosis. Trends Endocrinol Metab 20: 367-373.
29. Yirmiya R, Bab I, (2009) Major depression is a risk factor for low bone mineral density: a meta-analysis. Biol Psychiatry 66: 423-43.
30. Cizza G, Primma S, Coyle M, Gourgiotis L, Csako G, (2010) Depression and osteoporosis: a research synthesis with meta-analysis. Horm Metab Re 42: 467-482.
31. Williams LJ, Bjerkeset O, Langhammer A, Berk M, Pasco JA, et al. (2011) The association between depressive and anxiety symptoms and bone mineral density in the general population: the HUNT Study. J Affect Disord 131: 164-171.
32. Mussolino ME, Jonas BS, Looker AC, (2004) Depression and bone mineral density in young adults: results from NHANES III. Psychosom Med 66: 533-537.
33. Mussolino ME, (2005) Depression and hip fracture risk: the NHANES I epidemiologic follow-up study. Public Health Rep 120: 71-75.
34. Kahl KG, Greggersen W, Rudolf S, Stoeckelhuber BM, Bergmann-Koester CU, et al. (2006) Bone mineral density, bone turnover, and osteoprotegerin in depressed women with and without borderline personality disorder. Psychosom Med 68: 669-674.
35. Petronijevic M, Petronijevic N, Ivkovic M, Stefanović D, Radonjić N, et al. (2008) Low bone mineral density and high bone metabolism turnover in premenopausal women with unipolar depression. Bone 42: 582-590.
36. Michelson D, Stratakis C, Hill L, Reynolds J, Galliven E, et al. (1996) Bone mineral density in women with depression. N Engl J Med 335: 1176-1181.
37. Ozsoy S, Esel E, Turan MT, Kula M, Demir H, et al. (2005) Is there any alteration in bone mineral density in patients with depression? Turk Psikiyatri Derg 16: 77-82.
38. Reginster JY, Deroisy R, Paul I, Hansenne M, Ansseau M, (1999) Depressive vulnerability is not an independent risk factor for osteoporosis in postmenopausal women. Maturitas 33: 133-137.
39. Whooley MA, Cauley JA, Zmuda JM, Haney EM, Glynn NW, (2004) Depressive symptoms and bone mineral density in older men. J Geriatr Psychiatry Neurol 17: 88-92.
40. Yazici AE, Bagis S, Tot S, Sahin G, Yazici K, et al. (2005) Bone mineral density in premenopausal women with major depression. Joint Bone Spine 72: 540-543.
41. Halbreich U, Rojansky N, Palter S, Hreshchyshyn M, Kreeger J, et al. (1995) Decreased bone mineral density in medicated psychiatric patients. Psychosom Med 57: 485-491.
42. Michelson D, Stratakis C, Hill L, Reynolds J, Galliven E, et al. (1996) Bone mineral density in women with depression. N Engl J Med 16: 1176-1181.
43. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, et al. (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res 22: 465-475.
44. Bouxsein ML, Myburgh KH, van der Meulen MC, Lindenberger E, Marcus R, (1994) Age-related differences in cross-sectional geometry of the forearm bones in healthy women. Calcif Tissue Int 54: 113-118.
45. Burger H, van Daele PLA, Algra D, van den Ouweland FA, Grobbee DE, et al. (1994) The association between age and bone mineral density in men and women aged 55 years and over: The Rotterdam Study. Bone Miner 25: 1-13.
46. Ahlborg HG, Johnell O, Turner CH, Rannevik G, Karlsson MK, (2003) Bone loss and bone size after menopause. N Engl J Med 349: 327-334.
47. Emaus N, Berntsen GK, Joakimsen RM, Fønnebø V, (2005) Longitudinal changes in forearm bone mineral density in women and men aged 25-44 years: the Tromsø study: a population-based study. Am J Epidemiol 162: 633-643.
48. Matkovic V, Jelic T, Wardlaw GM, Ilich JZ, Goel PK, et al. (1994) Timing of peak bone mass in Caucasian females and its implication for the prevention of osteoporosis. J Clin Invest 93: 799-808.
49. Heaney RP, Abrams S, Dawson-Hughes B, Looker A, Marcus R, et al. (2000) Peak bone mass. Osteoporos Int 11: 985-1009.
50. Stetler C, Miller GE, (2011) Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research. Psychosom Med 73: 114-126.
51. Aihara M, Ida I, Yuuki N, Oshima A, Kumano H, et al. (2007) HPA axis dysfunction in unmedicated major depressive disorder and its normalization by pharmacotherapy correlates with alteration of neural activity in prefrontal cortex and limbic/paralimbic regions. Neuroimaging 155: 245-256.
52. Heuser I, Yassouridis A, Holsboer F, (1994) The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J Psychiatr Res 28: 341-356.
53. Kunugi H, Ida I, Owashi T, Kimura M, Inoue Y, et al. (2006) Assessment of the dexamethasone/CRH test as a state-dependent marker for hypothalamic-pituitaryadrenal (HPA) axis abnormalities in major depressive episode: a multicenter study. Neuropsychopharmacology 31: 212-220.
54. Krishnamurthy P, Romagni P, Torvik S, Gold PW, Charney DS, et al. (2008) Glucocorticoid receptor gene polymorphisms in premenopausal women with depression. Horm Metab Res 40: 194-198.
55. van Rossum EF, Koper JW, van den Beld AW, Uitterlinden AG, Arp P, et al. (2003) Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index. Clin Endocrinol 59: 585-592.
56. van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, et al. (2006) Polymorphisms of the glucocorticoid receptor gene and major depression. Biol Psychiatry 59: 681-688.
57. Nemeroff CB, (1996) The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions. Mol Psychiatry 1: 336-342.
58. Cizza G, Ronsaville DS, Kleitz H, Eskandari F, Mistry S, et al. (2012) Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power study. PLoS One 7 (1): e28912.
59. Adachi JD, Saag KG, Delmas PD, Liberman UA, Emkey RD, et al. (2001) Two-year effects of alendronate on bone mineral density and vertebral fracture in patients receiving glucocorticoids. Arthritis Rheum 4444: 202-211.
60. Gourlay M, Brown SA, (2004) Clinical considerations in premenopausal osteoporosis. Arch Intern Med 164: 603-614.
61. Bhalla A, (2010) Management of osteoporosis in a pre-menopausal woman. Best Pract Res Clin Rheumatol 24: 313-332.
62. Wu Q, Bencaz AF, Hentz JG, Crowell MD, (2012) Selective serotonin reuptake inhibitor treatment and risk of fractures: a meta-analysis of cohort and case-control studies. Osteoporos Int 23: 365-375.
63. Hoogendijk WJG, Lips P, Dik MG, Deeg DJ, Beekman AT, et al. (2008) Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults. Arch Gen Psychiatry 65: 508-512.
64. Zhao G, Ford ES, Li C, Balluz LS, (2010) No associations between serum concentrations of 25-hydroxyvitamin D and parathyroid hormone and depression among US adults. Br J Nutr 104: 1696-1702.