Bone and energy metabolism parameters in professional cyclists during the Giro d'Italia 3-weeks stage race

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Lombardi, Giovanni ^a   Lanteri, Patrizia ^a   Graziani, Rosa ^b   Colombini, Alessandra ^a   Banfi, Giuseppe ^a,c   Corsetti, Roberto ^d  

^a IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

^b CEDAL Lab   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d Liquigas Cannondale pro cycling team Medical board ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ADIPOCYTOKINE; ADIPONECTIN; ALKALINE PHOSPHATASE BONE ISOENZYME; HYDROCORTISONE; LEPTIN; OSTEOCALCIN; TARTRATE RESISTANT ACID PHOSPHATASE 5B; TESTOSTERONE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOCHEMISTRY; BONE METABOLISM; BONE TURNOVER; CONTROLLED STUDY; CYCLING; DOWN REGULATION; ENERGY CONSUMPTION; ENERGY EXPENDITURE; ENERGY METABOLISM; ENZYME IMMUNOASSAY; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; ITALY; METABOLIC PARAMETERS; METABOLIC REGULATION; OSTEOLYSIS; PROTEIN MODIFICATION; TESTOSTERONE BLOOD LEVEL; UPREGULATION;

ADIPOKINES; ANTHROPOMETRY; ATHLETES; BICYCLING; BIOLOGICAL MARKERS; BODY COMPOSITION; BONE AND BONES; ENERGY METABOLISM; HORMONES; HUMANS; KIDNEY; OSTEOCALCIN; TIME FACTORS;

EID: 84864401942     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042077     Document Type: Article

References (43)

1. Foster C, Hoyos J, Earnest C, Lucia A, ((2005)) Regulation of energy expenditure during prolonged athletic competition. Med Sci Sports Exerc 37:: 670--675.
2. Lucia A, Diaz B, Hoyos J, Fernandez C, Villa G, et al. ((2001)) Hormone levels of world class cyclists during the Tour of Spain stage race. Br J Sports Med 35:: 424--430.
3. Saris WH, van Erp-Baart MA, Brouns F, Westerterp KR, ten Hoor F, ((1989)) Study on food intake and energy expenditure during extreme sustained exercise: the Tour de France. Int J Sports Med 10 Suppl 1: S26--31.
4. Padilla S, Mujika I, Santisteban J, Impellizzeri FM, Goiriena JJ, ((2008)) Exercise intensity and load during uphill cycling in professional 3-week races. Eur J Appl Physiol 102:: 431--438.
5. Ihle R, Loucks AB, ((2004)) Dose-response relationships between energy availability and bone turnover in young exercising women. J Bone Miner Res 19:: 1231--1240.
6. Zanker CL, Swaine IL, ((2000)) Responses of bone turnover markers to repeated endurance running in humans under conditions of energy balance or energy restriction. Eur J Appl Physiol 83:: 434--440.
7. Chicharro JL, Lopez-Calderon A, Hoyos J, Martin-Velasco AI, Villa G, et al. ((2001)) Effects of an endurance cycling competition on resting serum insulin-like growth factor I (IGF-I) and its binding proteins IGFBP-1 and IGFBP-3. Br J Sports Med 35:: 303--307.
8. Corsetti R, Lombardi G, Lanteri P, Colombini A, Graziani R, et al. ((2012)) Haematological and iron metabolism parameters in professional cyclists during the Giro d'Italia 3-weeks stage race. Clin Chem Lab Med 50:: 949--956.
9. Chicharro JL, Hoyos J, Bandres F, Terrados N, Fernandez B, et al. ((2001)) Thyroid hormone levels during a 3-week professional road cycling competition. Horm Res 56:: 159--164.
10. McMurray RG, Hackney AC, ((2005)) Interactions of metabolic hormones, adipose tissue and exercise. Sports Med 35:: 393--412.
11. Fernandez-Garcia B, Lucia A, Hoyos J, Chicharro JL, Rodriguez-Alonso M, et al. ((2002)) The response of sexual and stress hormones of male pro-cyclists during continuous intense competition. Int J Sports Med 23:: 555--560.
12. Banfi G, Lombardi G, Colombini A, Lippi G, ((2010)) Bone metabolism markers in sports medicine. Sports Med. pp. 697--714.
13. Lombardi G, Colombini A, Freschi M, Tavana R, Banfi G, ((2011)) Seasonal variation of bone turnover markers in top-level female skiers. Eur J Appl Physiol 111:: 433--440.
14. Rector RS, Rogers R, Ruebel M, Hinton PS, ((2008)) Participation in road cycling vs running is associated with lower bone mineral density in men. Metabolism. pp. 226--232.
15. Nichols JF, Palmer JE, Levy SS, ((2003)) Low bone mineral density in highly trained male master cyclists. Osteoporos Int 14:: 644--649.
16. Olmedillas H, Gonzalez-Aguero A, Moreno LA, Casajus JA, Vicente-Rodriguez G, ((2011)) Bone related health status in adolescent cyclists. PLoS One 6:: e24841.
17. Confavreux CB, Levine RL, Karsenty G, ((2009)) A paradigm of integrative physiology, the crosstalk between bone and energy metabolisms. Mol Cell Endocrinol 310:: 21--29.
18. Confavreux CB, ((2011)) Bone: from a reservoir of minerals to a regulator of energy metabolism. Kidney Int. Suppl: S14-19.
19. Ducy P, ((2011)) The role of osteocalcin in the endocrine cross-talk between bone remodelling and energy metabolism. Diabetologia 54:: 1291--1297.
20. Bouassida A, Chamari K, Zaouali M, Feki Y, Zbidi A, et al. ((2010)) Review on leptin and adiponectin responses and adaptations to acute and chronic exercise. Br J Sports Med 44:: 620--630.
21. Vogt S, Heinrich L, Schumacher YO, Blum A, Roecker K, et al. ((2006)) Power output during stage racing in professional road cycling. Med Sci Sports Exerc 38:: 147--151.
22. Banfi G, Dolci A, ((2003)) Preanalytical phase of sport biochemistry and haematology. J Sports Med Phys Fitness 43:: 223--230.
23. Lippi G, Banfi G, Maffulli N, ((2010)) Preanalytical variability: the dark side of the moon in blood doping screening. Eur J Appl Physiol 109:: 1003--1005.
24. Meier C, Nguyen TV, Handelsman DJ, Schindler C, Kushnir MM, et al. ((2008)) Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study. Arch Intern Med 168:: 47--54.
25. Banfi G, Bauer K, Brand W, BuchbergerM (2002) Use Of Anticoagulants In Diagnostic Laboratory Investigations & Stability of blood, plasma and serum samples.
26. Colombini A, Corsetti R, Graziani R, Lombardi G, Lanteri P, et al. ((2012)) Evaluation of creatinine, cystatin C and eGFR by different equations in professional cyclists during the Giro d'Italia 3-weeks stage race. Scand J Clin Lab Invest 72:: 114--120.
27. Fernandez-Garcia B, Perez-Landaluce J, Rodriguez-Alonso M, Terrados N, ((2000)) Intensity of exercise during road race pro-cycling competition. Med Sci Sports Exerc 32:: 1002--1006.
28. Lucia A, Earnest C, Arribas C, ((2003)) The Tour de France: a physiological review. Scand J Med Sci Sports 13:: 275--283.
29. Wolf G, ((2008)) Energy regulation by the skeleton. Nutr Rev 66:: 229--233.
30. Ebert TR, Martin DT, Stephens B, Withers RT, ((2006)) Power output during a professional men's road-cycling tour. Int J Sports Physiol Perform 1:: 324--335.
31. Vogt S, Schumacher YO, Roecker K, Dickhuth HH, Schoberer U, et al. ((2007)) Power Output during the Tour de France. Int J Sports Med 28:: 756--761.
32. Vogt S, Roecker K, Schumacher YO, Pottgiesser T, Dickhuth HH, et al. ((2008)) Cadence-power-relationship during decisive mountain ascents at the Tour de France. Int J Sports Med 29:: 244--250.
33. Mouzopoulos G, Stamatakos M, Tzurbakis M, Tsembeli A, Manti C, et al. ((2007)) Changes of bone turnover markers after marathon running over 245 km. Int J Sports Med 28:: 576--579.
34. Maimoun L, Galy O, Manetta J, Coste O, Peruchon E, et al. ((2004)) Competitive season of triathlon does not alter bone metabolism and bone mineral status in male triathletes. Int J Sports Med 25:: 230--234.
35. Jurimae J, Purge P, Jurimae T, von Duvillard SP, ((2006)) Bone metabolism in elite male rowers: adaptation to volume-extended training. Eur J Appl Physiol 97:: 127--132.
36. Campion F, Nevill AM, Karlsson MK, Lounana J, Shabani M, et al. ((2010)) Bone status in professional cyclists. Int J Sports Med 31:: 511--515.
37. Smathers AM, Bemben MG, Bemben DA, ((2009)) Bone density comparisons in male competitive road cyclists and untrained controls. Med Sci Sports Exerc 41:: 290--296.
38. Wei J, Ducy P, ((2010)) Co-dependence of bone and energy metabolisms. Arch Biochem Biophys 503:: 35--40.
39. Dozio E, Corsi MM, Ruscica M, Passafaro L, Steffani L, et al. ((2011)) Adipokine actions on cartilage homeostasis. Adv Clin Chem 55:: 61--79.
40. Penteado VS, Castro CH, Pinheiro Mde M, Santana M, Bertolino S, et al. ((2010)) Diet, body composition, and bone mass in well-trained cyclists. J Clin Densitom 13:: 43--50.
41. Hinton PS, Rolleston A, Rehrer NJ, Hellemans IJ, Miller BF, ((2010)) Bone formation is increased to a greater extent than bone resorption during a cycling stage race. Appl Physiol Nutr Metab 35:: 344--349.
42. Duclos M, Corcuff JB, Rashedi M, Fougere V, Manier G, ((1996)) Does functional alteration of the gonadotropic axis occur in endurance trained athletes during and after exercise? A preliminary study. Eur J Appl Physiol Occup Physiol 73:: 427--433.
43. Hoogeveen AR, Zonderland ML, ((1996)) Relationships between testosterone, cortisol and performance in professional cyclists. Int J Sports Med 17:: 423--428.