The levels of circulating and urinary monocyte chemoattractant protein-1 are associated with chronic renal injury in obese men

Clinica Chimica Acta

Volumn 413, Issue 19-20, 2012, Pages 1647-1651

  Fu, Chia Po ^a   Lee, I Te ^a,b   Sheu, Wayne H H ^a,b   Lee, Wen Jane ^a,c   Liang, Kae Woei ^a,b,d   Lee, Wen Lieng ^a   Lin, Shih Yi ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c TUNGHAI UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Cystatin C; Inflammation; MCP 1; Obesity

Indexed keywords

CYSTATIN C; GLUCOSE; INSULIN; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADULT; ARTICLE; BODY FAT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; ESTIMATED GLOMERULUS FILTRATION RATE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS MODEL ASSESSMENT INSULIN RESISTANCE INDEX; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; KIDNEY FUNCTION; KIDNEY INJURY; MACROALBUMINURIA; MALE; MICROALBUMINURIA; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN URINE LEVEL; RENAL SYSTEM PARAMETERS; SYSTOLIC BLOOD PRESSURE; URINARY CYSTATIN C TO CREATININE RATIO; URINARY MONOCYTE CHEMOTACTIC PROTEIN 1 TO CREATININE RATIO; WAIST CIRCUMFERENCE;

ADIPOSE TISSUE; ADULT; ALBUMINURIA; BIOLOGICAL MARKERS; BODY MASS INDEX; CHEMOKINE CCL2; CREATININE; CYSTATIN C; GLOMERULAR FILTRATION RATE; HUMANS; INSULIN RESISTANCE; KIDNEY; MALE; MIDDLE AGED; MONOCYTES; OBESITY; RENAL INSUFFICIENCY, CHRONIC;

EID: 84864392517     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2012.05.008     Document Type: Article

References (57)

1. Despres J.P., Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006, 444:881-887.
2. Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
3. Van Gaal L.F., Mertens I.L., De Block C.E. Mechanisms linking obesity with cardiovascular disease. Nature 2006, 444:875-880.
4. Gelber R.P., Kurth T., Kausz A.T., et al. Association between body mass index and CKD in apparently healthy men. Am J Kidney Dis 2005, 46:871-880.
5. Hsu C.Y., McCulloch C.E., Iribarren C., Darbinian J., Go A.S. Body mass index and risk for end-stage renal disease. Ann Intern Med 2006, 144:21-28.
6. Hunley T.E., Ma L.J., Kon V. Scope and mechanisms of obesity-related renal disease. Curr Opin Nephrol Hypertens 2010, 19:227-234.
7. Ejerblad E., Fored C.M., Lindblad P., Fryzek J., McLaughlin J.K., Nyren O. Obesity and risk for chronic renal failure. J Am Soc Nephrol 2006, 17:1695-1702.
8. Fox C.S., Larson M.G., Leip E.P., Culleton B., Wilson P.W., Levy D. Predictors of new-onset kidney disease in a community-based population. JAMA 2004, 291:844-850.
9. Iseki K., Ikemiya Y., Kinjo K., Inoue T., Iseki C., Takishita S. Body mass index and the risk of development of end-stage renal disease in a screened cohort. Kidney Int 2004, 65:1870-1876.
10. Kambham N., Markowitz G.S., Valeri A.M., Lin J., D'Agati V.D. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int 2001, 59:1498-1509.
11. Serra A., Romero R., Lopez D., et al. Renal injury in the extremely obese patients with normal renal function. Kidney Int 2008, 73:947-955.
12. Berg A.H., Scherer P.E. Adipose tissue, inflammation, and cardiovascular disease. Circ Res 2005, 96:939-949.
13. Takahashi K., Mizuarai S., Araki H., et al. Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice. J Biol Chem 2003, 278:46654-46660.
14. Kanda H., Tateya S., Tamori Y., et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006, 116:1494-1505.
15. Malavazos A.E., Cereda E., Morricone L., Coman C., Corsi M.M., Ambrosi B. Monocyte chemoattractant protein 1: a possible link between visceral adipose tissue-associated inflammation and subclinical echocardiographic abnormalities in uncomplicated obesity. Eur J Endocrinol 2005, 153:871-877.
16. Tonelli M., Sacks F., Pfeffer M., Jhangri G.S., Curhan G. Biomarkers of inflammation and progression of chronic kidney disease. Kidney Int 2005, 68:237-245.
17. Keller C.R., Odden M.C., Fried L.F., et al. Kidney function and markers of inflammation in elderly persons without chronic kidney disease: the health, aging, and body composition study. Kidney Int 2007, 71:239-244.
18. Khan S.B., Cook H.T., Bhangal G., Smith J., Tam F.W., Pusey C.D. Antibody blockade of TNF-alpha reduces inflammation and scarring in experimental crescentic glomerulonephritis. Kidney Int 2005, 67:1812-1820.
19. Abrahamson M., Olafsson I., Palsdottir A., et al. Structure and expression of the human cystatin C gene. Biochem J 1990, 268:287-294.
20. Abrahamson M., Dalboge H., Olafsson I., Carlsen S., Grubb A. Efficient production of native, biologically active human cystatin C by Escherichia coli. FEBS Lett 1988, 236:14-18.
21. Dharnidharka V.R., Kwon C., Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis 2002, 40:221-226.
22. Rule A.D., Larson T.S., Bergstralh E.J., Slezak J.M., Jacobsen S.J., Cosio F.G. Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med 2004, 141:929-937.
23. Rule A.D., Bergstralh E.J., Slezak J.M., Bergert J., Larson T.S. Glomerular filtration rate estimated by cystatin C among different clinical presentations. Kidney Int 2006, 69:399-405.
24. Stevens L.A., Coresh J., Greene T., Levey A.S. Assessing kidney function-measured and estimated glomerular filtration rate. N Engl J Med 2006, 354:2473-2483.
25. Herget-Rosenthal S., Feldkamp T., Volbracht L., Kribben A. Measurement of urinary cystatin C by particle-enhanced nephelometric immunoassay: precision, interferences, stability and reference range. Ann Clin Biochem 2004, 41:111-118.
26. Herget-Rosenthal S., van Wijk J.A., Brocker-Preuss M., Bokenkamp A. Increased urinary cystatin C reflects structural and functional renal tubular impairment independent of glomerular filtration rate. Clin Biochem 2007, 40:946-951.
27. Koyner J.L., Bennett M.R., Worcester E.M., et al. Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int 2008, 74:1059-1069.
28. Rovin B.H., Doe N., Tan L.C. Monocyte chemoattractant protein-1 levels in patients with glomerular disease. Am J Kidney Dis 1996, 27:640-646.
29. Brown Z., Robson R.L., Westwick J. Regulation and expression of chemokines: potential role in glomerulonephritis. J Leukoc Biol 1996, 59:75-80.
30. Banba N., Nakamura T., Matsumura M., Kuroda H., Hattori Y., Kasai K. Possible relationship of monocyte chemoattractant protein-1 with diabetic nephropathy. Kidney Int 2000, 58:684-690.
31. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
32. Levey A.S., Bosch J.P., Lewis J.B., Greene T., Rogers N., Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999, 130:461-470.
33. Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., Ferrante A.W. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003, 112:1796-1808.
34. Wellen K.E., Hotamisligil G.S. Inflammation, stress, and diabetes. J Clin Invest 2005, 115:1111-1119.
35. Xu H., Barnes G.T., Yang Q., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003, 112:1821-1830.
36. Sartipy P., Loskutoff D.J. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci U S A 2003, 100:7265-7270.
37. Cox C.L., Stanhope K.L., Schwarz J.M., et al. Circulating concentrations of monocyte chemoattractant protein-1, plaminogen activator inhibitor-1, and soluble leukocyte adhesion molecule-1 in overweight/obese men and woman consuming fructose- or glucose-sweetened beverages for 10weeks. J Clin Endocrinol Metab 2011, 96:E2034-E2038.
38. Mine S., Okada Y., Tanikawa T., Kawahara C., Tabata T., Tanaka Y. Increased expression levels of monocyte CCR2 and monocyte chemoattractant protein-1 in patients with diabetes mellitus. Biochem Biophys Res Commun 2006, 344:780-785.
39. Christiansen T., Richelsen B., Bruun J.M. Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects. Int J Obes (Lond) 2005, 29:146-150.
40. Bruun J.M., Lihn A.S., Pedersen S.B., Richelsen B. Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT. J Clin Endocrinol Metab 2005, 90:2282-2289.
41. Charo I.F., Taubman M.B. Chemokines in the pathogenesis of vascular disease. Circ Res 2004, 95:858-866.
42. Tateya S., Tamori Y., Kawaguchi T., Kanda H., Kasuga M. An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice. Endocrinology 2010, 151:971-979.
43. Rose C.E., Sung S.S., Fu S.M. Significant involvement of CCL2 (MCP-1) in inflammatory disorders of the lung. Microcirculation 2003, 10:273-288.
44. Eardley K.S., Zehnder D., Quinkler M., et al. The relationship between albuminuria, MCP-1/CCL2, and interstitial macrophages in chronic kidney disease. Kidney Int 2006, 69:1189-1197.
45. Chow F.Y., Nikolic-Paterson D.J., Ma F.Y., Ozols E., Rollins B.J., Tesch G.H. Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice. Diabetologia 2007, 50:471-480.
46. Ikezumi Y., Hurst L.A., Masaki T., Atkins R.C., Nikolic-Paterson D.J. Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation. Kidney Int 2003, 63:83-95.
47. Parikh C.R., Lu J.C., Coca S.G., Devarajan P. Tubular proteinuria in acute kidney injury: a critical evaluation of current status and future promise. Ann Clin Biochem 2010, 47:301-312.
48. Muntner P., Winston J., Uribarri J., Mann D., Fox C.S. Overweight, obesity, and elevated serum cystatin C levels in adults in the United States. Am J Med 2008, 121:341-348.
49. Knight E.L., Verhave J.C., Spiegelman D., et al. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int 2004, 65:1416-1421.
50. Stevens L.A., Schmid C.H., Greene T., et al. Factors other than glomerular filtration rate affect serum cystatin C levels. Kidney Int 2009, 75:652-660.
51. Naour N., Fellahi S., Renucci J.F., et al. Potential contribution of adipose tissue to elevated serum cystatin C in human obesity. Obesity (Silver Spring) 2009, 17:2121-2126.
52. Naour N., Rouault C., Fellahi S., et al. Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation. J Clin Endocrinol Metab 2010, 95:1861-1868.
53. Bemelmans M.H., Gouma D.J., Buurman W.A. Tissue distribution and clearance of soluble murine TNF receptors in mice. Cytokine 1994, 6:608-615.
54. Fukami A., Yamagishi S., Adachi H., et al. High white blood cell count and low estimated glomerular filtration rate are independently associated with serum level of monocyte chemoattractant protein-1 in a general population. Clin Cardiol 2011, 34:189-194.
55. Vaziri N.D., Xu Z.G., Shahkarami A., Huang K.T., Rodriguez-Iturbe B., Natarajan R. Role of AT-1 receptor in regulation of vascular MCP-1, IL-6, PAI-1, MAP kinase, and matrix expressions in obesity. Kidney Int 2005, 68:2787-2793.
56. Upadhyay A., Larson M.G., Guo C.Y., et al. Inflammation, kidney function and albuminuria in the Framingham Offspring cohort. Nephrol Dial Transplant 2011, 26:920-926.
57. Chapman H.A., Riese R.J., Shi G.P. Emerging roles for cysteine proteases in human biology. Annu Rev Physiol 1997, 59:63-88.