Role of nuclear factor-κB in oxidative stress associated with rabies virus Infection of adult rat dorsal root ganglion neurons

Journal of Virology

Volumn 86, Issue 15, 2012, Pages 8139-8146

  Kammouni, Wafa ^a   Hasan, Leena ^a   Saleh, Ali ^b   Wood, Heidi ^a,c   Fernyhough, Paul ^a,b   Jackson, Alan C ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b ST BONIFACE GENERAL HOSPITAL   (Canada)

^c PUBLIC HEALTH AGENCY OF CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; CILIARY NEUROTROPHIC FACTOR RECEPTOR; GENOMIC RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN P50; SN 50; SYNAPTOTAGMIN I; TUBULIN;

ADULT ANIMAL; ANIMAL CELL; ARTICLE; CELL NUCLEUS MEMBRANE; CELL SWELLING; CONTROLLED STUDY; CYTOPLASM VESICLE; LIPID PEROXIDATION; MALE; MOLECULAR DYNAMICS; NERVE FIBER GROWTH; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RABIES; RABIES VIRUS; RAT; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL; SPINAL GANGLION; TRANSCRIPTION REGULATION; VIRUS STRAIN; WESTERN BLOTTING;

ANIMALS; CELL LINE; CRICETINAE; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; LIPID PEROXIDATION; MALE; NEURONS; NF-KAPPA B P50 SUBUNIT; OXIDATIVE STRESS; PEPTIDES; RABIES; RABIES VIRUS; RATS; RATS, SPRAGUE-DAWLEY;

RABIES VIRUS; RATTUS;

EID: 84864386428     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00550-12     Document Type: Article

References (36)

1. Akude E, Zherebitskaya E, Chowdhury SKR, Girling K, Fernyhough P. 2010. 4-Hydroxy-2-nonenal induces mitochondrial dysfunction and ab-errant axonal outgrowth in adult sensory neurons that mimics features of diabetic neuropathy. Neurotox. Res. 17:28-38.
2. Baloh RH, Schmidt RE, Pestronk A, Milbrandt J. 2007. Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations. J. Neurosci. 27:422-430.
3. Bowie A, et al. 2000. A46R and A52R from vaccinia virus are antagonists of host IL-1 and Toll-like receptor signaling. Proc. Natl. Acad. Sci. U. S. A. 97:10162-10167.
4. Ebenezer GJ, et al. 2007. Denervation of skin in neuropathies: the sequence of axonal and Schwann cell changes in skin biopsies. Brain 130: 2703-2714.
5. Fernyhough P, et al. 1999. Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy. Diabetes 48:881-889.
6. Fernyhough P, et al. 2005. Activation of nuclear factor-κB via endogenous tumor necrosis factor regulates survival of axotomized adult sensory neurons. J. Neurosci. 25:1682-1690.
7. Fu ZF, Jackson AC. 2005. Neuronal dysfunction and death in rabies virus infection. J. Neurovirol. 11:101-106.
8. Grilli M, Memo M. 1999. Nuclear factor-kappaB/Rel proteins: a point of convergence of signalling pathways relevant in neuronal function and dysfunction. Biochem. Pharmacol. 57:1-7.
9. Gutierrez H, O'Keeffe GW, Gavalda N, Gallagher D, Davies AM. 2008. Nuclear factor kappa B signaling either stimulates or inhibits neurite growth depending on the phosphorylation status of p65/RelA. J. Neurosci. 28:8246-8256.
10. Hayden MS, Ghosh S. 2012. NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev. 26:203-234.
11. Iwasaki Y, Tobita M. 2002. Pathology, p 283-306. In Jackson AC, Wunner WH (ed), Rabies. Academic Press, San Diego, CA.
12. Jackson AC. 2007. Pathogenesis, p 341-381. In Jackson AC, WunnerWH (ed), Rabies. Elsevier Academic Press, London, United Kingdom.
13. Jackson AC. 2011. Therapy of human rabies. Adv. Virus Res. 79:365-375.
14. Jackson AC, Kammouni W, Zherebitskaya E, Fernyhough P. 2010. Role of oxidative stress in rabies virus infection of adult mouse dorsal root ganglion neurons. J. Virol. 84:4697-4705.
15. Jackson AC, Wunner WH. 2007. Rabies, 2nd ed. Elsevier Academic Press, London, United Kingdom.
16. Joo M, et al. 2005. Hepatitis C virus core protein suppresses NF-κB activation and cyclooxygenase-2 expression by direct interaction with IκB kinaseβ. J. Virol. 79:7648-7657.
17. Lauria G, et al. 2003. Axonal swellings predict the degeneration of epidermal nerve fibers in painful neuropathies. Neurology 61:631-636.
18. Nadin-Davis SA, Sheen M, Wandeler AI. 2009. Development of realtime reverse transcriptase polymerase chain reaction methods for human rabies diagnosis. J. Med. Virol. 81:1484-1497.
19. Obrosova IG, et al. 2005. Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications. Diabetes 54:234-242.
20. Oie KL, Pickup DJ. 2001. Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-κB activation. Virology 288:175-187.
21. Petersen DR, Doorn JA. 2004. Reactions of 4-hydroxynonenal with proteins and cellular targets. Free Radic. Biol. Med. 37:937-945.
22. Revilla Y, et al. 1998. Inhibition of nuclear factor κB activation by a virus-encoded I_B-like protein. J. Biol. Chem. 273:5405-5411.
23. Ridder DA, Schwaninger M. 2009. NF-kappaB signaling in cerebral ischemia. Neuroscience 158:995-1006.
24. Rossiter JP, Jackson AC. 2007. Pathology, p 383-409. In Jackson AC, Wunner WH (ed), Rabies. Elsevier Academic Press, London, United Kingdom.
25. Russell JW, et al. 2002. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J. 16:1738-1748.
26. Saleh A, et al. 2011. Tumor necrosis factor- elevates neurite outgrowth through an NF-κB-dependent pathway in cultured adult sensory neurons: diminished expression in diabetes may contribute to sensory neuropathy. Brain Res. 1423:87-95.
27. Sango K, Yanagisawa H, Komuta Y, Si Y, Kawano H. 2008. Neuroprotective properties of ciliary neurotrophic factor for cultured adult rat dorsal root ganglion neurons. Histochem. Cell Biol. 130:669-679.
28. Santoro MG, Rossi A, Amici C. 2003. NF-κB and virus infection: who controls whom. EMBO J. 22:2552-2560.
29. Sarnico I, et al. 2009. NF-kappaB dimers in the regulation of neuronal survival. Int. Rev. Neurobiol. 85:351-362.
30. Schmidt RE, Beaudet LN, Plurad SB, Dorsey DA. 1997. Axonal cytoskeletal pathology in aged and diabetic human sympathetic autonomic ganglia. Brain Res. 769:375-383.
31. Scott CA, Rossiter JP, Andrew RD, Jackson AC. 2008. Structural abnormalities in neurons are sufficient to explain the clinical disease and fatal outcome in experimental rabies in yellow fluorescent protein-expressing transgenic mice. J. Virol. 82:513-521.
32. Teng FY, Tang BL. 2010. NF-kappaB signaling in neurite growth and neuronal survival. Rev. Neurosci. 21:299-313.
33. Verkhratsky A, Fernyhough P. 2008. Mitochondrial malfunction and Ca2+dyshomeostasis drive neuronal pathology in diabetes. Cell Calcium 44:112-122.
34. Wakeley PR, et al. 2005. Development of a real-time, TaqMan reverse transcription-PCR assay for detection and differentiation of lyssavirus genotypes 1, 5, and 6. J. Clin. Microbiol. 43:2786-2792.
35. Waxman SG. 2006. Ions, energy and axonal injury: towards a molecular neurology of multiple sclerosis. Trends Mol. Med. 12:192-195.
36. Zherebitskaya E, Akude E, Smith DR, Fernyhough P. 2009. Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress. Diabetes 58:1356-1364.