메뉴 건너뛰기




Volumn 413, Issue 19-20, 2012, Pages 1583-1590

Interleukin 6 and C-reactive protein in esophageal cancer

Author keywords

Adenocarcinoma of esophagus; C reactive protein; Esophageal cancer; Esophageal squamous cell cancer; Interleukin 6

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; C REACTIVE PROTEIN; CYCLOOXYGENASE 2 INHIBITOR; INTERLEUKIN 6; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84864383761     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2012.05.009     Document Type: Review
Times cited : (50)

References (102)
  • 1
    • 4043144935 scopus 로고    scopus 로고
    • Epidemiology of upper gastrointestinal malignancies
    • Crew K.D., Neugut A. Epidemiology of upper gastrointestinal malignancies. Semin Oncol 2004, 31:450-464.
    • (2004) Semin Oncol , vol.31 , pp. 450-464
    • Crew, K.D.1    Neugut, A.2
  • 2
    • 13744258445 scopus 로고    scopus 로고
    • The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence
    • Pohn H., Welch H.G. The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 2005, 97:142-146.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 142-146
    • Pohn, H.1    Welch, H.G.2
  • 4
    • 33846582706 scopus 로고    scopus 로고
    • Prognostic value of microvessel density, matrix metalloproteinase-9 and p53 protein expression in esophageal cancer
    • El-Shahat M., Lotfy M., Fahmy L., Abouel-Nour M.F., El-Kenawy Ael-M. Prognostic value of microvessel density, matrix metalloproteinase-9 and p53 protein expression in esophageal cancer. J Egypt Natl Cancer Inst 2004, 16:224-230.
    • (2004) J Egypt Natl Cancer Inst , vol.16 , pp. 224-230
    • El-Shahat, M.1    Lotfy, M.2    Fahmy, L.3    Abouel-Nour, M.F.4    El-Kenawy, A.-M.5
  • 5
    • 33750454439 scopus 로고    scopus 로고
    • Predictive and prognostic molecular markers in outcome of esophageal cancer
    • Vallbohmer D., Lenz H.J. Predictive and prognostic molecular markers in outcome of esophageal cancer. Dis Esophagus 2006, 19:425-432.
    • (2006) Dis Esophagus , vol.19 , pp. 425-432
    • Vallbohmer, D.1    Lenz, H.J.2
  • 6
    • 78649373414 scopus 로고    scopus 로고
    • Etiology and risk factors for esophageal carcinoma
    • Lundell L.R. Etiology and risk factors for esophageal carcinoma. Dig Dis 2010, 28:641-644.
    • (2010) Dig Dis , vol.28 , pp. 641-644
    • Lundell, L.R.1
  • 7
    • 2342530749 scopus 로고    scopus 로고
    • Eurocare-3 summary: cancer survival in Europe at the end of the 20th century
    • Coleman M.P., Gatta G., Verdecchia A., et al. Eurocare-3 summary: cancer survival in Europe at the end of the 20th century. Ann Oncol 2003, 14:128-149.
    • (2003) Ann Oncol , vol.14 , pp. 128-149
    • Coleman, M.P.1    Gatta, G.2    Verdecchia, A.3
  • 8
    • 33845485257 scopus 로고    scopus 로고
    • Epidemiology and pathogenesis of esophageal cancer
    • Holmes R.S., Vaughan T.L. Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol 2007, 17:2-9.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 2-9
    • Holmes, R.S.1    Vaughan, T.L.2
  • 9
    • 0036846327 scopus 로고    scopus 로고
    • Diet, obesity and reflux in the etiology of adenocarcinomas of the esophagus and gastric cardia in humans
    • Mayne S.T., Navarro S.A. Diet, obesity and reflux in the etiology of adenocarcinomas of the esophagus and gastric cardia in humans. J Nutr 2002, 132:3467S-3470S.
    • (2002) J Nutr , vol.132
    • Mayne, S.T.1    Navarro, S.A.2
  • 10
    • 21244474867 scopus 로고    scopus 로고
    • Body mass, tobacco and alcohol and risk of esophageal, gastric cardia, and gastric non-cardia adenocarcinoma among men and women in a nested case-control study
    • Lindblad M., Rodríguez L.A., Lagergren J. Body mass, tobacco and alcohol and risk of esophageal, gastric cardia, and gastric non-cardia adenocarcinoma among men and women in a nested case-control study. Cancer Causes Control 2005, 16:285-294.
    • (2005) Cancer Causes Control , vol.16 , pp. 285-294
    • Lindblad, M.1    Rodríguez, L.A.2    Lagergren, J.3
  • 11
    • 0037243474 scopus 로고    scopus 로고
    • Barrett's oesophagus: optimal strategies for prevention and treatment
    • Fass R., Sampliner R.E. Barrett's oesophagus: optimal strategies for prevention and treatment. Drugs 2003, 63:555-564.
    • (2003) Drugs , vol.63 , pp. 555-564
    • Fass, R.1    Sampliner, R.E.2
  • 12
    • 0642376411 scopus 로고    scopus 로고
    • EMR as salvage treatment for patients with locoregional failure of definitive chemoradiotherapy for esophageal cancer
    • Hattori S., Muto M., Ohtsu A., et al. EMR as salvage treatment for patients with locoregional failure of definitive chemoradiotherapy for esophageal cancer. Gastrointest Endosc 2003, 58:65-70.
    • (2003) Gastrointest Endosc , vol.58 , pp. 65-70
    • Hattori, S.1    Muto, M.2    Ohtsu, A.3
  • 13
    • 0034535179 scopus 로고    scopus 로고
    • Evaluation of HPV, CMV, HSV and EBV in esophageal squamous cell carcinomas from a high-incidence area of China
    • Chang F., Syrjänen S., Shen Q., et al. Evaluation of HPV, CMV, HSV and EBV in esophageal squamous cell carcinomas from a high-incidence area of China. Anticancer Res 2000, 20:3935-3940.
    • (2000) Anticancer Res , vol.20 , pp. 3935-3940
    • Chang, F.1    Syrjänen, S.2    Shen, Q.3
  • 14
    • 18744386460 scopus 로고    scopus 로고
    • Evaluation of the prevalence of human papillomavirus and Epstein-Barr virus in esophageal squamous cell carcinomas
    • Lyronis I.D., Baritaki S., Bizakis I., Tsardi M., Spandidos D.A. Evaluation of the prevalence of human papillomavirus and Epstein-Barr virus in esophageal squamous cell carcinomas. Int J Biol Markers 2005, 20:5-10.
    • (2005) Int J Biol Markers , vol.20 , pp. 5-10
    • Lyronis, I.D.1    Baritaki, S.2    Bizakis, I.3    Tsardi, M.4    Spandidos, D.A.5
  • 15
    • 33645506107 scopus 로고    scopus 로고
    • Evidence of human papilloma virus infection and its epidemiology in esophageal squamous cell carcinoma
    • Yao P.F., Li G.C., Li J., et al. Evidence of human papilloma virus infection and its epidemiology in esophageal squamous cell carcinoma. World J Gastroenterol 2006, 12:1352-1355.
    • (2006) World J Gastroenterol , vol.12 , pp. 1352-1355
    • Yao, P.F.1    Li, G.C.2    Li, J.3
  • 16
    • 79954448525 scopus 로고    scopus 로고
    • Cancer in cohort of HIV-infected population: prevalence and clinical characteristics
    • Zhang Y.X., Gui X.E., Zhong Y.H., Rong Y.P., Yan Y.J. Cancer in cohort of HIV-infected population: prevalence and clinical characteristics. J Cancer Res Clin Oncol 2011, 137:609-614.
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 609-614
    • Zhang, Y.X.1    Gui, X.E.2    Zhong, Y.H.3    Rong, Y.P.4    Yan, Y.J.5
  • 18
    • 0042563122 scopus 로고    scopus 로고
    • Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma
    • Shimada H., Nabeya Y., Tagawa M., et al. Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma. Cancer Sci 2003, 94:628-632.
    • (2003) Cancer Sci , vol.94 , pp. 628-632
    • Shimada, H.1    Nabeya, Y.2    Tagawa, M.3
  • 19
    • 85021062648 scopus 로고
    • Serological reactions in pneumonia with a nonprotein somatic fraction of pneumococcus
    • Tillett W.S., Francis T. Serological reactions in pneumonia with a nonprotein somatic fraction of pneumococcus. J Exp Med 1930, 52:561-585.
    • (1930) J Exp Med , vol.52 , pp. 561-585
    • Tillett, W.S.1    Francis, T.2
  • 20
    • 85025416904 scopus 로고
    • The occurrence during acute infections of a protein not normally present in the blood. I. Distribution of the reactive protein in patients' sera and the effect of calcium on the flocculation reaction with C polysaccharide of pneumococcus
    • Abernethy T.J., Avery O.T. The occurrence during acute infections of a protein not normally present in the blood. I. Distribution of the reactive protein in patients' sera and the effect of calcium on the flocculation reaction with C polysaccharide of pneumococcus. J Exp Med 1941, 73:173-182.
    • (1941) J Exp Med , vol.73 , pp. 173-182
    • Abernethy, T.J.1    Avery, O.T.2
  • 21
    • 0025651707 scopus 로고
    • Rotation function studies of human C-reactive protein
    • Myles D.A., Rule S.A., DeLucas L.J., et al. Rotation function studies of human C-reactive protein. J Mol Biol 1990, 216:491-496.
    • (1990) J Mol Biol , vol.216 , pp. 491-496
    • Myles, D.A.1    Rule, S.A.2    DeLucas, L.J.3
  • 22
    • 0034040639 scopus 로고    scopus 로고
    • Immunohistochemical localization of modified C-reactive protein antigen in normal vascular tissue
    • Diehl E.E., Haines G.K., Radosevich J.A., Potempa L.A. Immunohistochemical localization of modified C-reactive protein antigen in normal vascular tissue. Am J Med Sci 2000, 319:79-83.
    • (2000) Am J Med Sci , vol.319 , pp. 79-83
    • Diehl, E.E.1    Haines, G.K.2    Radosevich, J.A.3    Potempa, L.A.4
  • 23
    • 0023273456 scopus 로고
    • Expression, detection, and assay of neoantigen (neo-CRP) associated with a free, human C-reactive subunit
    • Potempa L.A., Siegel J.N., Fiedel B.A., Potempa R.T., Gewurz H. Expression, detection, and assay of neoantigen (neo-CRP) associated with a free, human C-reactive subunit. Mol Immunol 1987, 24:531-541.
    • (1987) Mol Immunol , vol.24 , pp. 531-541
    • Potempa, L.A.1    Siegel, J.N.2    Fiedel, B.A.3    Potempa, R.T.4    Gewurz, H.5
  • 24
    • 0024325622 scopus 로고
    • Identification and partial characterization of multiple native and neoantigenic epitopes of human C-reactive protein by using monoclonal antibodies
    • Ying S.C., Gewurz H., Kinoshita C.M., Potempa L.A., Siegel J.N. Identification and partial characterization of multiple native and neoantigenic epitopes of human C-reactive protein by using monoclonal antibodies. J Immunol 1989, 143:221-228.
    • (1989) J Immunol , vol.143 , pp. 221-228
    • Ying, S.C.1    Gewurz, H.2    Kinoshita, C.M.3    Potempa, L.A.4    Siegel, J.N.5
  • 26
    • 0017714715 scopus 로고
    • Interactions of C-reactive protein with the first component of human complement
    • Claus D.R., Siegel J., Petras K., Osmand A.P., Gewurz H. Interactions of C-reactive protein with the first component of human complement. J Immunol 1977, 119:187-192.
    • (1977) J Immunol , vol.119 , pp. 187-192
    • Claus, D.R.1    Siegel, J.2    Petras, K.3    Osmand, A.P.4    Gewurz, H.5
  • 28
    • 0030668555 scopus 로고    scopus 로고
    • Interleukin-6-dependent and independent regulation of the human C-reactive protein gene
    • Weinhold B., Ruther U. Interleukin-6-dependent and independent regulation of the human C-reactive protein gene. Biochem J 1997, 327:425-429.
    • (1997) Biochem J , vol.327 , pp. 425-429
    • Weinhold, B.1    Ruther, U.2
  • 29
    • 0029155329 scopus 로고
    • C-reactive protein expression in Hep3B cells is exerted at the transcriptional level
    • Zhang D., Jiang S.L., Rzewnicki D., Samols D., Kushner I. C-reactive protein expression in Hep3B cells is exerted at the transcriptional level. Biochem J 1995, 310:143-148.
    • (1995) Biochem J , vol.310 , pp. 143-148
    • Zhang, D.1    Jiang, S.L.2    Rzewnicki, D.3    Samols, D.4    Kushner, I.5
  • 30
    • 0025841744 scopus 로고
    • Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6
    • Baumann H., Schendel P. Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6. J Biol Chem 1991, 266:20424-20427.
    • (1991) J Biol Chem , vol.266 , pp. 20424-20427
    • Baumann, H.1    Schendel, P.2
  • 32
    • 0025190310 scopus 로고
    • Transforming growth factor B1 regulates production of acute phase proteins
    • Mackiewicz A., Ganapathi M.K., Schultz D., et al. Transforming growth factor B1 regulates production of acute phase proteins. Proc Natl Acad Sci U S A 1990, 87:1491-1495.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1491-1495
    • Mackiewicz, A.1    Ganapathi, M.K.2    Schultz, D.3
  • 33
    • 0022536320 scopus 로고
    • C-reactive protein is produced by a small number of normal human peripheral blood lymphocytes
    • Kuta A.E., Baum L.L. C-reactive protein is produced by a small number of normal human peripheral blood lymphocytes. J Exp Med 1986, 164:321-326.
    • (1986) J Exp Med , vol.164 , pp. 321-326
    • Kuta, A.E.1    Baum, L.L.2
  • 34
    • 0027501319 scopus 로고
    • Membrane associated C-reactive protein on rat liver macrophages is synthesized within the macrophages, expressed as neo-C-reactive protein and bound through a C-reactive protein-specific membrane receptor
    • Egenhofer C., Alsdorff K., Fehsel K., Kolb-Bachofen V. Membrane associated C-reactive protein on rat liver macrophages is synthesized within the macrophages, expressed as neo-C-reactive protein and bound through a C-reactive protein-specific membrane receptor. Hepatology 1995, 18:1216-1223.
    • (1995) Hepatology , vol.18 , pp. 1216-1223
    • Egenhofer, C.1    Alsdorff, K.2    Fehsel, K.3    Kolb-Bachofen, V.4
  • 35
    • 33645461474 scopus 로고    scopus 로고
    • Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells
    • Kang D.H., Park S.K., Lee I.K., Johnson R.J. Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells. J Am Soc Nephrol 2005, 16:3553-3562.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3553-3562
    • Kang, D.H.1    Park, S.K.2    Lee, I.K.3    Johnson, R.J.4
  • 36
    • 0029949314 scopus 로고    scopus 로고
    • Expression of C-reactive protein by alveolar macrophages
    • Dong Q., Wright J.R. Expression of C-reactive protein by alveolar macrophages. J Immunol 1996, 156:4815-4820.
    • (1996) J Immunol , vol.156 , pp. 4815-4820
    • Dong, Q.1    Wright, J.R.2
  • 37
    • 0035115645 scopus 로고    scopus 로고
    • Expression of C-reactive protein in the human respiratory tract
    • Gould J.M., Weiser J.N. Expression of C-reactive protein in the human respiratory tract. Infect Immun 2001, 69:1747-1754.
    • (2001) Infect Immun , vol.69 , pp. 1747-1754
    • Gould, J.M.1    Weiser, J.N.2
  • 38
    • 0034869253 scopus 로고    scopus 로고
    • Human C-reactive protein: expression, structure, and function
    • Volanakis J.E. Human C-reactive protein: expression, structure, and function. Mol Immunol 2001, 38:189-197.
    • (2001) Mol Immunol , vol.38 , pp. 189-197
    • Volanakis, J.E.1
  • 39
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker P.M., Hennekens C.H., Buring J.E., Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000, 342:836-843.
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 40
  • 41
    • 70449397951 scopus 로고    scopus 로고
    • C-reactive protein and malignancy: clinico-pathological association and therapeutic implication
    • Wang C.S., Sun C.F. C-reactive protein and malignancy: clinico-pathological association and therapeutic implication. Chang Gung Med J 2009, 32:471-482.
    • (2009) Chang Gung Med J , vol.32 , pp. 471-482
    • Wang, C.S.1    Sun, C.F.2
  • 42
    • 33748117796 scopus 로고    scopus 로고
    • Interleukin-6: discovery of pleiotropic cytokine
    • Kishimoto T. Interleukin-6: discovery of pleiotropic cytokine. Arthritis Res Ther 2006, 8:S2.
    • (2006) Arthritis Res Ther , vol.8
    • Kishimoto, T.1
  • 43
    • 0035983251 scopus 로고    scopus 로고
    • Identification of a novel IL-6 isoform binding to the endogenous IL-6 receptor
    • Bihl M.P., Heinimann K., Rüdiger J.J., et al. Identification of a novel IL-6 isoform binding to the endogenous IL-6 receptor. Am J Resp Cell Mol Biol 2002, 27:48-56.
    • (2002) Am J Resp Cell Mol Biol , vol.27 , pp. 48-56
    • Bihl, M.P.1    Heinimann, K.2    Rüdiger, J.J.3
  • 44
    • 0024364807 scopus 로고
    • The molecular biology of beta-2-interferon/interleukin 6 (IFN beta 2)
    • Bowcock A.M., Ray A., Erlich H.A., Sehgal P.B. The molecular biology of beta-2-interferon/interleukin 6 (IFN beta 2). Ann NY Acad Sci 1989, 557:345-352.
    • (1989) Ann NY Acad Sci , vol.557 , pp. 345-352
    • Bowcock, A.M.1    Ray, A.2    Erlich, H.A.3    Sehgal, P.B.4
  • 45
    • 0025216240 scopus 로고
    • Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene
    • Hattori M., Abraham L.J., Northemann W., Fey G.H. Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene. Proc Natl Acad Sci U S A 1990, 87:2364-2368.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 2364-2368
    • Hattori, M.1    Abraham, L.J.2    Northemann, W.3    Fey, G.H.4
  • 46
    • 0025986128 scopus 로고
    • Differential induction of interleukin-6 production by monocytes, endothelial cells and smooth muscle cells
    • Helle M., Boeije L., Pascual-Salcedo D., Aarden L. Differential induction of interleukin-6 production by monocytes, endothelial cells and smooth muscle cells. Prog Clin Biol Res 1991, 367:61-71.
    • (1991) Prog Clin Biol Res , vol.367 , pp. 61-71
    • Helle, M.1    Boeije, L.2    Pascual-Salcedo, D.3    Aarden, L.4
  • 49
    • 23944441266 scopus 로고    scopus 로고
    • Hobisch A interleukin-6 regulation of prostate cancer cell growth
    • Culig Z., Steiner H., Bartsch G. Hobisch A interleukin-6 regulation of prostate cancer cell growth. J Cell Biochem 2005, 95:497-505.
    • (2005) J Cell Biochem , vol.95 , pp. 497-505
    • Culig, Z.1    Steiner, H.2    Bartsch, G.3
  • 50
    • 0037455841 scopus 로고    scopus 로고
    • Circulating interleukin-6 predictors survival in patients with metastatic breast cancer
    • Salgado R., Junius S., Benoy I., et al. Circulating interleukin-6 predictors survival in patients with metastatic breast cancer. Int J Cancer 2003, 103:642-646.
    • (2003) Int J Cancer , vol.103 , pp. 642-646
    • Salgado, R.1    Junius, S.2    Benoy, I.3
  • 51
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich P.C., Castell J.V., Andus T. Interleukin-6 and the acute phase response. Biochem J 1990, 265:621-636.
    • (1990) Biochem J , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 52
    • 0026333033 scopus 로고
    • Interleukin-6 and its relation to inflammation and disease
    • Hirano T. Interleukin-6 and its relation to inflammation and disease. Clin Immunol Immunopathol 1992, 62:S60-S65.
    • (1992) Clin Immunol Immunopathol , vol.62
    • Hirano, T.1
  • 53
    • 0024365825 scopus 로고
    • Interleukin 3 and interleukin 6 synergistically promote the proliferation and differentiation of malignant plasma cell precursors in multiple myeloma
    • Bergui L., Schena M., Gaidano G., Riva M., Caligaris-Cappio F. Interleukin 3 and interleukin 6 synergistically promote the proliferation and differentiation of malignant plasma cell precursors in multiple myeloma. J Exp Med 1989, 170:613-619.
    • (1989) J Exp Med , vol.170 , pp. 613-619
    • Bergui, L.1    Schena, M.2    Gaidano, G.3    Riva, M.4    Caligaris-Cappio, F.5
  • 55
    • 0026604636 scopus 로고
    • Is interleukin 6 the physiological regulator of thrombopoiesis?
    • Straneva J.E., van Besien K.W., Derigs G., Hoffman R. Is interleukin 6 the physiological regulator of thrombopoiesis?. Exp Hematol 1992, 20:47-50.
    • (1992) Exp Hematol , vol.20 , pp. 47-50
    • Straneva, J.E.1    van Besien, K.W.2    Derigs, G.3    Hoffman, R.4
  • 56
    • 0022499547 scopus 로고
    • Complementary DNA for novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
    • Hirano T., Yasukawa K., Harada H., et al. Complementary DNA for novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 1986, 324:73-76.
    • (1986) Nature , vol.324 , pp. 73-76
    • Hirano, T.1    Yasukawa, K.2    Harada, H.3
  • 57
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.1    Werb, Z.2
  • 58
    • 3543102542 scopus 로고    scopus 로고
    • Inflammation and necrosis promote tumour growth
    • Vakkila J., Lotze M. Inflammation and necrosis promote tumour growth. Nat Rev Immunol 2004, 4:641-648.
    • (2004) Nat Rev Immunol , vol.4 , pp. 641-648
    • Vakkila, J.1    Lotze, M.2
  • 59
    • 11344282264 scopus 로고    scopus 로고
    • Addicted to death: invasive cancer and the immune response to unscheduled cell death
    • Zeh Hr, Lotze M. Addicted to death: invasive cancer and the immune response to unscheduled cell death. J Immunother 2005, 28:1-9.
    • (2005) J Immunother , vol.28 , pp. 1-9
    • Zeh, H.1    Lotze, M.2
  • 60
    • 0024369797 scopus 로고
    • Interleukin 6 is a potent myeloma cell growth factor in patients with aggressive multiple myeloma
    • Zhang X.G., Klein B., Bataille R. Interleukin 6 is a potent myeloma cell growth factor in patients with aggressive multiple myeloma. Blood 1989, 74:11-13.
    • (1989) Blood , vol.74 , pp. 11-13
    • Zhang, X.G.1    Klein, B.2    Bataille, R.3
  • 61
    • 0025853227 scopus 로고
    • Serum levels of interleukin-6 in multiple myeloma and other hematological disorders: correlation with disease activity and other prognostic parameters
    • Nachbaur D.M., Herold M., Maneschg A., Huber H. Serum levels of interleukin-6 in multiple myeloma and other hematological disorders: correlation with disease activity and other prognostic parameters. Ann Hematol 1991, 62:54-58.
    • (1991) Ann Hematol , vol.62 , pp. 54-58
    • Nachbaur, D.M.1    Herold, M.2    Maneschg, A.3    Huber, H.4
  • 62
    • 0027302498 scopus 로고
    • Interleukin-6 gene expression in multiple myeloma: a characteristic of immature tumor cells
    • Hata H., Xiao H., Petrucci M.T., Woodliff J., Chang R., Epstein J. Interleukin-6 gene expression in multiple myeloma: a characteristic of immature tumor cells. Blood 1993, 81:3357-3364.
    • (1993) Blood , vol.81 , pp. 3357-3364
    • Hata, H.1    Xiao, H.2    Petrucci, M.T.3    Woodliff, J.4    Chang, R.5    Epstein, J.6
  • 63
    • 0027303024 scopus 로고
    • Interleukin-6 (IL6) functions as an autocrine growth factor in cervical carcinomas in vitro
    • Eustace D., Han X., Gooding R., Rowbottom A., Riches P., Heyderman E. Interleukin-6 (IL6) functions as an autocrine growth factor in cervical carcinomas in vitro. Gynecol Oncol 1993, 50:15-19.
    • (1993) Gynecol Oncol , vol.50 , pp. 15-19
    • Eustace, D.1    Han, X.2    Gooding, R.3    Rowbottom, A.4    Riches, P.5    Heyderman, E.6
  • 64
    • 2842605597 scopus 로고
    • Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-β
    • Chen L., Mory Y., Zilberstein A., Revel M. Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-β. Proc Natl Acad Sci 1988, 85:8037-8041.
    • (1988) Proc Natl Acad Sci , vol.85 , pp. 8037-8041
    • Chen, L.1    Mory, Y.2    Zilberstein, A.3    Revel, M.4
  • 65
    • 0027858352 scopus 로고
    • Growth inhibition of human lung cancer cell lines by interleukin 6 in vitro: a possible role in tumor growth via an autocrine mechanism
    • Takizawa H., Ohtoshi T., Ohta K., et al. Growth inhibition of human lung cancer cell lines by interleukin 6 in vitro: a possible role in tumor growth via an autocrine mechanism. Cancer Res 1993, 1553:4175-4181.
    • (1993) Cancer Res , vol.1553 , pp. 4175-4181
    • Takizawa, H.1    Ohtoshi, T.2    Ohta, K.3
  • 66
    • 0026049122 scopus 로고
    • Interleukin-4 inhibits growth of multiple myelomas by suppressing interleukin-6 expression
    • Herrmann F., Andreeff M., Gruss H.J., Brach M.A., Lübbert M., Mertelsmann R. Interleukin-4 inhibits growth of multiple myelomas by suppressing interleukin-6 expression. Blood 1991, 78:2070-2074.
    • (1991) Blood , vol.78 , pp. 2070-2074
    • Herrmann, F.1    Andreeff, M.2    Gruss, H.J.3    Brach, M.A.4    Lübbert, M.5    Mertelsmann, R.6
  • 67
    • 0036912873 scopus 로고    scopus 로고
    • Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma
    • Huang S., Wu M., Wang H., Yang C., Kuo M., Lin J. Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma. J Gastroenterol Hepatol 2002, 17:1165-1169.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 1165-1169
    • Huang, S.1    Wu, M.2    Wang, H.3    Yang, C.4    Kuo, M.5    Lin, J.6
  • 68
    • 79952015621 scopus 로고    scopus 로고
    • Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients
    • Ravishankaran P., Karunanithi R. Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients. World J Surg Oncol 2011, 9:18-23.
    • (2011) World J Surg Oncol , vol.9 , pp. 18-23
    • Ravishankaran, P.1    Karunanithi, R.2
  • 69
    • 20444467988 scopus 로고    scopus 로고
    • High serum levels of interleukin-6 in endometrial carcinoma are associated with uterine serous papillary histology, a highly aggressive and chemotherapy-resistant variant of endometrial cancer
    • Bellone S., Watts K., Cane' S., et al. High serum levels of interleukin-6 in endometrial carcinoma are associated with uterine serous papillary histology, a highly aggressive and chemotherapy-resistant variant of endometrial cancer. Gynecol Oncol 2005, 98:92-98.
    • (2005) Gynecol Oncol , vol.98 , pp. 92-98
    • Bellone, S.1    Watts, K.2    Cane', S.3
  • 70
    • 0035459901 scopus 로고    scopus 로고
    • Changes of serum IL-6 and CRP after chemotherapy in patients with ovarian carcinoma
    • Zakrzewska I., Pozański J. Changes of serum IL-6 and CRP after chemotherapy in patients with ovarian carcinoma. Pol Merkuriusz Lek 2001, 11:210-213.
    • (2001) Pol Merkuriusz Lek , vol.11 , pp. 210-213
    • Zakrzewska, I.1    Pozański, J.2
  • 71
    • 33846798310 scopus 로고    scopus 로고
    • Interleukin-6, interleukin-10, and vascular endothelial growth factor in metastatic renal cell carcinoma: prognostic value of interleukin-6
    • Negrier S., Perol D., Menetrier-Caux C., et al. Interleukin-6, interleukin-10, and vascular endothelial growth factor in metastatic renal cell carcinoma: prognostic value of interleukin-6. J Clin Oncol 2005, 23:1044-1045.
    • (2005) J Clin Oncol , vol.23 , pp. 1044-1045
    • Negrier, S.1    Perol, D.2    Menetrier-Caux, C.3
  • 72
    • 67649801143 scopus 로고    scopus 로고
    • Clinical significances of preoperative serum interleukin-6 and C-reactive protein level in operable gastric cancer
    • Kim D.K., Oh S.Y., Kwon H.C., et al. Clinical significances of preoperative serum interleukin-6 and C-reactive protein level in operable gastric cancer. BMC Cancer 2009, 9:155-163.
    • (2009) BMC Cancer , vol.9 , pp. 155-163
    • Kim, D.K.1    Oh, S.Y.2    Kwon, H.C.3
  • 73
    • 53849129529 scopus 로고    scopus 로고
    • Serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels in colorectal adenoma and cancer patients
    • Groblewska M., Mroczko B., Wereszczyńska-Siemiatkowska U., et al. Serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels in colorectal adenoma and cancer patients. Clin Chem Lab Med 2008, 46:1423-1428.
    • (2008) Clin Chem Lab Med , vol.46 , pp. 1423-1428
    • Groblewska, M.1    Mroczko, B.2    Wereszczyńska-Siemiatkowska, U.3
  • 74
    • 77955642845 scopus 로고    scopus 로고
    • Diagnostic usefulness of serum interleukin 6 (IL-6) and C-reactive protein (CRP) in the differentiation between pancreatic cancer and chronic pancreatitis
    • Mroczko B., Groblewska M., Gryko M., Kedra B., Szmitkowski M. Diagnostic usefulness of serum interleukin 6 (IL-6) and C-reactive protein (CRP) in the differentiation between pancreatic cancer and chronic pancreatitis. J Clin Lab Anal 2010, 24:256-261.
    • (2010) J Clin Lab Anal , vol.24 , pp. 256-261
    • Mroczko, B.1    Groblewska, M.2    Gryko, M.3    Kedra, B.4    Szmitkowski, M.5
  • 75
    • 2942616855 scopus 로고    scopus 로고
    • Serum interleukin-6 levels correlate with malnutrition and survival in patients with advanced non-small cell lung cancer
    • Songür N., Kuru B., Kalkan F., Ozdilekcan C., Cakmak H., Hizel N. Serum interleukin-6 levels correlate with malnutrition and survival in patients with advanced non-small cell lung cancer. Tumori 2004, 90:196-200.
    • (2004) Tumori , vol.90 , pp. 196-200
    • Songür, N.1    Kuru, B.2    Kalkan, F.3    Ozdilekcan, C.4    Cakmak, H.5    Hizel, N.6
  • 76
    • 79958156564 scopus 로고    scopus 로고
    • Comparison between clinical significance of serum proinflammatory proteins (IL-6 and CRP) and classic tumor markers (CEA and CA 19-9) in gastric cancer
    • Łukaszewicz-Zajac M., Mroczko B., Gryko M., Kedra B., Szmitkowski M. Comparison between clinical significance of serum proinflammatory proteins (IL-6 and CRP) and classic tumor markers (CEA and CA 19-9) in gastric cancer. Clin Exp Med 2011, 11:89-96.
    • (2011) Clin Exp Med , vol.11 , pp. 89-96
    • Łukaszewicz-Zajac, M.1    Mroczko, B.2    Gryko, M.3    Kedra, B.4    Szmitkowski, M.5
  • 77
    • 84860390434 scopus 로고    scopus 로고
    • Elevated pre-treatment levels of plasma C-reactive protein are associated with poor prognosis after breast cancer: a cohort study
    • Allin K.H., Nordestgaard B.G., Flyger H., Bojesen S.E. Elevated pre-treatment levels of plasma C-reactive protein are associated with poor prognosis after breast cancer: a cohort study. Breast Cancer Res 2011, 13:R55.
    • (2011) Breast Cancer Res , vol.13
    • Allin, K.H.1    Nordestgaard, B.G.2    Flyger, H.3    Bojesen, S.E.4
  • 78
    • 79956214581 scopus 로고    scopus 로고
    • Preoperative elevation of serum C-reactive protein as an independent prognostic indicator for gastric cancer
    • Nozoe T., Iguchi T., Adachi E., Matsukuma A., Ezaki T. Preoperative elevation of serum C-reactive protein as an independent prognostic indicator for gastric cancer. Surg Today 2011, 41:510-513.
    • (2011) Surg Today , vol.41 , pp. 510-513
    • Nozoe, T.1    Iguchi, T.2    Adachi, E.3    Matsukuma, A.4    Ezaki, T.5
  • 79
    • 0028784135 scopus 로고
    • Cytokine mRNA expression patterns in human esophageal cancer cell lines
    • Oka M., Hirose K., Iizuka N., et al. Cytokine mRNA expression patterns in human esophageal cancer cell lines. J Interferon Cytokine Res 1995, 15:1005-1009.
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 1005-1009
    • Oka, M.1    Hirose, K.2    Iizuka, N.3
  • 80
    • 0030478812 scopus 로고    scopus 로고
    • The influence of interleukin-6 on the growth of human esophageal cancer cell lines
    • Oka M., Iizuka N., Yamamoto K., et al. The influence of interleukin-6 on the growth of human esophageal cancer cell lines. J Interferon Cytokine Res 1996, 16:1001-1006.
    • (1996) J Interferon Cytokine Res , vol.16 , pp. 1001-1006
    • Oka, M.1    Iizuka, N.2    Yamamoto, K.3
  • 81
    • 9344266888 scopus 로고    scopus 로고
    • Relationship between serum levels of interleukin 6, various disease parameters and malnutrition in patients with esophageal squamous cell carcinoma
    • Oka M., Iizuka N., Yamamoto K., et al. Relationship between serum levels of interleukin 6, various disease parameters and malnutrition in patients with esophageal squamous cell carcinoma. Cancer Res 1996, 56:2776-2780.
    • (1996) Cancer Res , vol.56 , pp. 2776-2780
    • Oka, M.1    Iizuka, N.2    Yamamoto, K.3
  • 82
    • 0344441877 scopus 로고    scopus 로고
    • Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways
    • Leu C.M., Wong F.H., Chang C., Huang S.F., Hu C.P. Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. Oncogene 2003, 22:7809-7818.
    • (2003) Oncogene , vol.22 , pp. 7809-7818
    • Leu, C.M.1    Wong, F.H.2    Chang, C.3    Huang, S.F.4    Hu, C.P.5
  • 83
    • 33845265094 scopus 로고    scopus 로고
    • Elevated tumour interleukin-1beta is associated with systemic inflammation: a marker of reduced survival in gastro-oesophageal cancer
    • Deans D.A., Wigmore S.J., Gilmour H., Paterson-Brown S., Ross J.A., Fearon K.C. Elevated tumour interleukin-1beta is associated with systemic inflammation: a marker of reduced survival in gastro-oesophageal cancer. Br J Cancer 2006, 95:1568-1575.
    • (2006) Br J Cancer , vol.95 , pp. 1568-1575
    • Deans, D.A.1    Wigmore, S.J.2    Gilmour, H.3    Paterson-Brown, S.4    Ross, J.A.5    Fearon, K.C.6
  • 84
    • 0037456675 scopus 로고    scopus 로고
    • Immunohistochemical expression of C-reactive protein in squamous cell carcinoma of the esophagus-significance as a tumor marker
    • Nozoe T., Korenaga D., Futatsugi M., Saeki H., Maehara Y., Sugimachi K. Immunohistochemical expression of C-reactive protein in squamous cell carcinoma of the esophagus-significance as a tumor marker. Cancer Lett 2003, 192:89-95.
    • (2003) Cancer Lett , vol.192 , pp. 89-95
    • Nozoe, T.1    Korenaga, D.2    Futatsugi, M.3    Saeki, H.4    Maehara, Y.5    Sugimachi, K.6
  • 85
    • 77954690798 scopus 로고    scopus 로고
    • C-reactive protein -717C>T genetic polymorphism associates with esophagectomy-induced stress hyperglycemia
    • Motoyama S., Miura M., Hinai Y., Maruyama K., Murata K., Ogawa J. C-reactive protein -717C>T genetic polymorphism associates with esophagectomy-induced stress hyperglycemia. World J Surg 2010, 34:1001-1007.
    • (2010) World J Surg , vol.34 , pp. 1001-1007
    • Motoyama, S.1    Miura, M.2    Hinai, Y.3    Maruyama, K.4    Murata, K.5    Ogawa, J.6
  • 86
    • 0032990516 scopus 로고    scopus 로고
    • Expression and up-regulation of interleukin-6 in oesophageal carcinoma cells by n-sodium butyrate
    • Wang L.S., Chow K.C., Wu C.W. Expression and up-regulation of interleukin-6 in oesophageal carcinoma cells by n-sodium butyrate. Br J Cancer 1999, 80:1617-1622.
    • (1999) Br J Cancer , vol.80 , pp. 1617-1622
    • Wang, L.S.1    Chow, K.C.2    Wu, C.W.3
  • 87
    • 79953094796 scopus 로고    scopus 로고
    • Esophageal carcinosarcoma presenting as a fever with elevated serum interleukin-6
    • Hayama S., Okushiba S., Shichinohe T., Hirano S., Tanaka E., Kondo S. Esophageal carcinosarcoma presenting as a fever with elevated serum interleukin-6. Ann Thorac Surg 2011, 91:1288-1290.
    • (2011) Ann Thorac Surg , vol.91 , pp. 1288-1290
    • Hayama, S.1    Okushiba, S.2    Shichinohe, T.3    Hirano, S.4    Tanaka, E.5    Kondo, S.6
  • 88
    • 39849101635 scopus 로고    scopus 로고
    • Acute-phase response proteins are related to cachexia and accelerated angiogenesis in gastroesophageal cancers
    • Krzystek-Korpacka M., Matusiewicz M., Diakowska D., et al. Acute-phase response proteins are related to cachexia and accelerated angiogenesis in gastroesophageal cancers. Clin Chem Lab Med 2008, 46:359-364.
    • (2008) Clin Chem Lab Med , vol.46 , pp. 359-364
    • Krzystek-Korpacka, M.1    Matusiewicz, M.2    Diakowska, D.3
  • 89
    • 33745475012 scopus 로고    scopus 로고
    • Significance of preoperative C-reactive protein as a parameter of the perioperative course and long-term prognosis in squamous cell carcinoma and adenocarcinoma of the oesophagus
    • Gockel I., Dirksen K., Messow C.M., Junginger T. Significance of preoperative C-reactive protein as a parameter of the perioperative course and long-term prognosis in squamous cell carcinoma and adenocarcinoma of the oesophagus. World J Gastroenterol 2006, 12:3746-3750.
    • (2006) World J Gastroenterol , vol.12 , pp. 3746-3750
    • Gockel, I.1    Dirksen, K.2    Messow, C.M.3    Junginger, T.4
  • 90
    • 0041708071 scopus 로고    scopus 로고
    • Elevation of preoperative serum C-reactive protein level is related to poor prognosis in esophageal squamous cell carcinoma
    • Shimada H., Nabeya Y., Okazumi S., et al. Elevation of preoperative serum C-reactive protein level is related to poor prognosis in esophageal squamous cell carcinoma. J Surg Oncol 2003, 83:248-252.
    • (2003) J Surg Oncol , vol.83 , pp. 248-252
    • Shimada, H.1    Nabeya, Y.2    Okazumi, S.3
  • 91
    • 0034808015 scopus 로고    scopus 로고
    • Significance of preoperative elevation of serum C-reactive protein as an indicator of prognosis in esophageal carcinoma
    • Nozoe T., Saeki H., Sugimachi K. Significance of preoperative elevation of serum C-reactive protein as an indicator of prognosis in esophageal carcinoma. Am J Surg 2001, 182:197-201.
    • (2001) Am J Surg , vol.182 , pp. 197-201
    • Nozoe, T.1    Saeki, H.2    Sugimachi, K.3
  • 92
    • 29144492820 scopus 로고    scopus 로고
    • Elevated serum levels of C-reactive protein are indicative of a poor prognosis in patients with esophageal cancer
    • Guillem P., Triboulet J. Elevated serum levels of C-reactive protein are indicative of a poor prognosis in patients with esophageal cancer. Dis Esophagus 2005, 18:146-150.
    • (2005) Dis Esophagus , vol.18 , pp. 146-150
    • Guillem, P.1    Triboulet, J.2
  • 93
    • 84859640183 scopus 로고    scopus 로고
    • Higher importance of interleukin 6 than classic tumor markers (carcinoembryonic antigen and squamous cell cancer antigen) in the diagnosis of esophageal cancer patients
    • [Online] Available at: Acces
    • Łukaszewicz-Zajac M, Mroczko B, Kozłowski M, Nikliński J, Laudański J, Szmitkowski M. Higher importance of interleukin 6 than classic tumor markers (carcinoembryonic antigen and squamous cell cancer antigen) in the diagnosis of esophageal cancer patients. Dis Esophagus [Online] Available at: Accessed on 17 March 2012. http://onlinelibrary.wiley.com/doi/10.1111/j.1442-2050.2011.01242.x/pdf.
    • Dis Esophagus
    • Łukaszewicz-Zajac, M.1    Mroczko, B.2    Kozłowski, M.3    Nikliński, J.4    Laudański, J.5    Szmitkowski, M.6
  • 94
    • 79851470620 scopus 로고    scopus 로고
    • Overexpression of Interleukin-6 suppresses cisplatin-induced cytotoxicity in esophageal squamous cell carcinoma cells
    • Suchi K., Fujiwara H., Okamura S., et al. Overexpression of Interleukin-6 suppresses cisplatin-induced cytotoxicity in esophageal squamous cell carcinoma cells. Anticancer Res 2011, 31:67-75.
    • (2011) Anticancer Res , vol.31 , pp. 67-75
    • Suchi, K.1    Fujiwara, H.2    Okamura, S.3
  • 95
    • 78650666975 scopus 로고    scopus 로고
    • Elevated serum CRP levels after induction chemoradiotherapy reflect poor treatment response in association with IL-6 in serum and local tumor site in patients with advanced esophageal cancer
    • Fujiwara H., Suchi K., Okamura S., et al. Elevated serum CRP levels after induction chemoradiotherapy reflect poor treatment response in association with IL-6 in serum and local tumor site in patients with advanced esophageal cancer. J Surg Oncol 2011, 103:62-68.
    • (2011) J Surg Oncol , vol.103 , pp. 62-68
    • Fujiwara, H.1    Suchi, K.2    Okamura, S.3
  • 98
    • 79954543947 scopus 로고    scopus 로고
    • Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells
    • Zhang H.Y., Zhang Q., Zhang X., et al. Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells. Am J Physiol Gastrointest Liver Physiol 2011, 300:G454-G460.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.300
    • Zhang, H.Y.1    Zhang, Q.2    Zhang, X.3
  • 99
    • 12144287275 scopus 로고    scopus 로고
    • Increased expression and secretion of interleukin-6 in patients with Barrett's esophagus
    • Dvorakova K., Payne C.M., Ramsey L., et al. Increased expression and secretion of interleukin-6 in patients with Barrett's esophagus. Clin Cancer Res 2004, 10:2020-2028.
    • (2004) Clin Cancer Res , vol.10 , pp. 2020-2028
    • Dvorakova, K.1    Payne, C.M.2    Ramsey, L.3
  • 100
    • 34848856813 scopus 로고    scopus 로고
    • Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to Barrett's esophagus
    • Dvorak K., Chavarria M., Payne C.M., et al. Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to Barrett's esophagus. Clin Cancer Res 2007, 13:5305-5313.
    • (2007) Clin Cancer Res , vol.13 , pp. 5305-5313
    • Dvorak, K.1    Chavarria, M.2    Payne, C.M.3
  • 101
    • 33745595547 scopus 로고    scopus 로고
    • Prostaglandins as mediators of COX-2 derived carcinogenesis in gastrointestinal tract
    • Konturek P.C., Kania J., Burnat G., Hahn E.G., Konturek S.J. Prostaglandins as mediators of COX-2 derived carcinogenesis in gastrointestinal tract. J Physiol Pharmacol 2005, 56:57-73.
    • (2005) J Physiol Pharmacol , vol.56 , pp. 57-73
    • Konturek, P.C.1    Kania, J.2    Burnat, G.3    Hahn, E.G.4    Konturek, S.J.5
  • 102
    • 0037219463 scopus 로고    scopus 로고
    • Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and metaanalysis
    • Corley D.A., Kerlikowske K., Verma R., et al. Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and metaanalysis. Gastroenterology 2003, 124:47-56.
    • (2003) Gastroenterology , vol.124 , pp. 47-56
    • Corley, D.A.1    Kerlikowske, K.2    Verma, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.