Structural insight into African horsesickness virus infection

Journal of Virology

Volumn 86, Issue 15, 2012, Pages 7858-7866

  Manole, Violeta ^a   Laurinmäki, Pasi ^a   Van Wyngaardt, Wouter ^b   Potgieter, Christiaan A ^b,e   Wright, Isabella M ^b,e   Venter, Gert J ^b   van Dijk, Alberdina A ^c   Sewell, B Trevor ^d   Butcher, Sarah J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b ONDERSTEPOORT VETERINARY INSTITUTE   (South Africa)

^c NORTH WEST UNIVERSITY   (South Africa)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e Deltamune (Pty) Ltd   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; HELICASE; PROTEIN VP2; PROTEIN VP3; RNA POLYMERASE;

AFRICAN HORSE SICKNESS; AFRICAN HORSE SICKNESS VIRUS; AFRICAN HORSE SICKNESS VIRUS SEROTYPE 4; AFRICAN HORSE SICKNESS VIRUS SEROTYPE 7; ANIMAL CELL; ARTICLE; BLUETONGUE ORBIVIRUS; CONTROLLED STUDY; INTERMETHOD COMPARISON; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA SEQUENCE; SEQUENCE ANALYSIS; STRAIN IDENTIFICATION; STRUCTURE ANALYSIS; VIRION; VIRUS GENOME; VIRUS IDENTIFICATION; VIRUS MORPHOLOGY; VIRUS REPLICATION; VIRUS STRAIN;

AFRICAN HORSE SICKNESS; AFRICAN HORSE SICKNESS VIRUS; ANIMALS; CAPSID PROTEINS; CERCOPITHECUS AETHIOPS; HORSES; MODELS, MOLECULAR; RNA REPLICASE; RNA, DOUBLE-STRANDED; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS; VIRAL CORE PROTEINS; VIRION;

AFRICAN HORSE SICKNESS VIRUS 4; AFRICAN HORSESICKNESS VIRUS; BLUETONGUE VIRUS; EQUIDAE; ORBIVIRUS;

EID: 84864378100     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00517-12     Document Type: Article

References (74)

1. Adrian M, Dubochet J, Lepault J, McDowall AW. 1984. Cryo-electron microscopy of viruses. Nature 308:32-36.
2. Basak AK, Gouet P, Grimes J, Roy P, Stuart D. 1996. Crystal structure of the top domain of African horse sickness virus VP7: comparisons with bluetongue virus VP7. J. Virol. 70:3797-3806.
3. Belhouchet M, et al. 2011. Detection of a fourth orbivirus non-structural protein. PLoS One 6:e25697. doi:10.1371/journal.pone.0025697.
4. Bentley L, Fehrsen J, Jordaan F, Huismans H, du Plessis DH. 2000. Identification of antigenic regions on VP2 of African horsesickness virus serotype 3 by using phage-displayed epitope libraries. J. Gen. Virol. 81: 993-1000.
5. Bremer CW. 1976. A gel electrophoretic study of the protein and nucleic acid components of African horsesickness virus. Onderstepoort J. Vet. Res. 43:193-200.
6. Bremer CW, Huismans H, Van Dijk AA. 1990. Characterization and cloning of the African horsesickness virus genome. J. Gen. Virol. 71:793-799.
7. Burrage TG, Trevejo R, Stone-Marschat M, Laegreid WW. 1993. Neutralizing epitopes of African horsesickness virus serotype 4 are located on VP2. Virology 196:799-803.
8. Burroughs JN, et al. 1994. Purification and properties of virus particles, infectious subviral particles, cores and VP7 crystals of African horsesickness virus serotype 9. J. Gen. Virol. 75:1849-1857.
9. Carrillo-Tripp M, et al. 2009. VIPERdb2: an enhanced and web API enabled relational database for structural virology. Nucleic Acids Res. 37: D436-D442.
10. Castillo-Olivares J, et al. 2011. A modified vaccinia Ankara virus (MVA) vaccine expressing African horsesickness virus (AHSV) VP2 protects against AHSV challenge in an IFNAR_/_ mouse model. PLoS One 6:e16503. doi:10.1371/journal.pone.0016503.
11. Chen JZ, et al. 2009. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc. Natl. Acad. Sci. U. S. A. 106:10644-10648.
12. Coetzer JA, Erasmus BJ. 1994. African horsesickness, p 460-475. In Coetzer JA, Thomson CR, Tustin RC (ed), Infectious disease of livestock with special reference to southern Africa, vol 1. Oxford University Press, Oxford, United Kingdom.
13. Darpel KE, et al. 2011. Saliva proteins of vector Culicoides modify structure and infectivity of bluetongue virus particles. PLoS One 6:e17545. doi:10.1371/journal.pone.0017545.
14. Diprose JM, et al. 2001. Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core. EMBO J. 20:7229-7239.
15. du Plessis M, Cloete M, Aitchison H, Van Dijk AA. 1998. Protein aggregation complicates the development of baculovirus-expressed African horsesickness virus serotype 5 VP2 subunit vaccines. Onderstepoort J. Vet. Res. 65:321-329.
16. Erasmus BJ. 1973. The pathogenesis of African horsesickness, p 1-11. In Bryans JT, Gerber H (ed), Proceedings of the Third International Conference on Equine Infectious Diseases. Equine infectious diseases, vol III. S. Karger, Basel, Switzerland.
17. Firth AE. 2008. Bioinformatic analysis suggests that the orbivirus VP6 cistron encodes an overlapping gene. Virol. J. 5:48.
18. Forzan M, Marsh M, Roy P. 2007. Bluetongue virus entry into cells. J. Virol. 81:4819-4827.
19. Forzan M, Wirblich C, Roy P. 2004. A capsid protein of nonenveloped bluetongue virus exhibits membrane fusion activity. Proc. Natl. Acad. Sci. U. S. A. 101:2100-2105.
20. Gouet P, et al. 1999. The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography. Cell 97:481-490.
21. Goujon M, et al. 2010. A new bioinformatics analysis tools framework at EMBL-EBI. Nucleic Acids Res. 38:W695-W699.
22. Grimes JM, et al. 1998. The atomic structure of the bluetongue virus core. Nature 395:470-478.
23. Grubman MJ, Lewis SA. 1992. Identification and characterization of the structural and nonstructural proteins of African horsesickness virus and determination of the genome coding assignments. Virology 186:444-451.
24. Harauz G, van Heel M. 1986. Similarity measures between images. Exact filters for general geometry of 3D reconstructions. Optik 73:146-156.
25. Hassan SH, Wirblich C, Forzan M, Roy P. 2001. Expression and functional characterization of bluetongue virus VP5 protein: role in cellular permeabilization. J. Virol. 75:8356-8367.
26. Hassan SS, Roy P. 1999. Expression and functional characterization of bluetongue virus VP2 protein: role in cell entry. J. Virol. 73:9832-9842.
27. Hewat EA, Booth TF, Roy P. 1992. Structure of bluetongue virus particles by cryoelectron microscopy. J. Struct. Biol. 109:61-69.
28. Hewat EA, Booth TF, Wade RH, Roy P. 1992. 3-D reconstruction of bluetongue virus tubules using cryoelectron microscopy. J. Struct. Biol. 108:35-48.
29. Heymann JB. 2001. Bsoft: image and molecular processing in electron microscopy. J. Struct. Biol. 133:156-169.
30. Howell PG. 1960. The 1960 epizootic of African horsesickness in the Middle East and SW Asia. J. South Afr. Vet. Assoc. 31:329-335.
31. Howell PG. 1962. The isolation and identification of further antigenic types of African horsesickness virus. Onderstepoort J. Vet. Res. 29:139-149.
32. Huiskonen JT, et al. 2006. Structure of the bacteriophage π6 nucleocapsid suggests a mechanism for sequential RNA packaging. Structure 14: 1039-1048.
33. Huismans H, van der Walt NT, Cloete M, Erasmus BJ. 1987. Isolation of a capsid protein of bluetongue virus that induces a protective immune response in sheep. Virology 157:172-179.
34. Jäälinoja HT, Huiskonen JT, Butcher SJ. 2007. Electron cryomicroscopy comparison of the architectures of the enveloped bacteriophages π6 and π8. Structure 15:157-167.
35. Larkin MA, et al. 2007. Clustal W and Clustal X version 2.0. Bioinformatics 23:2947-2948.
36. Lubroth J. 1988. African horsesickness and the epizootic in Spain 1987. Equine Pract. 10:26-33.
37. Lupas A, Van Dyke M, Stock J. 1991. Predicting coiled coils from protein sequences. Science 252:1162-1164.
38. Marchi PR, et al. 1995. Proteolytic cleavage of VP2, an outer capsid protein of African horsesickness virus, by species-specific serum proteases enhances infectivity in Culicoides. J. Gen. Virol. 76:2607-2611.
39. Martinez-Torrecuadrada JL, Casal JI. 1995. Identification of a linear neutralization domain in the protein VP2 of African horsesickness virus. Virology 210:391-399.
40. Matsuo E, Celma CC, Roy P. 2010. A reverse genetics system of African horsesickness virus reveals existence of primary replication. FEBS Lett. 584:3386-3391.
41. McIntosh BM. 1958. Immunological types of horsesickness virus and their significance in immunization. Onderstepoort J. Vet. Res. 27:465-538.
42. Meiswinkel R, Paweska JT. 2003. Evidence for a new field Culicoides vector of African horsesickness in South Africa. Prev. Vet. Med. 60:243-253.
43. Meiswinkel R, van Rijn P, Leijs P, Goffredo M. 2007. Potential new Culicoides vector of bluetongue virus in northern Europe. Vet. Rec. 161: 564-565.
44. Mellor PS. 1992. Culicoides as potential orbivirus vectors in Europe, p 278-283. In Walton E, Osburn BI (ed), Bluetongue, African horsesickness, and related orbiviruses. CRC Press Inc, Boca Raton, FL.
45. Mellor PS, Boorman J, Baylis M. 2000. Culicoides biting midges: their role as arbovirus vectors. Annu. Rev. Entomol. 45:307-340.
46. Mellor PS, Carpenter S, White DM. 2009. Bluetongue virus in the insect host, p 295-320. In Mellor PSB, et al (ed), Bluetongue. Elsevier, Paris, France.
47. Mellor PS, Hamblin C. 2004. African horsesickness. Vet. Res. 35:445-466.
48. Mellor PS, Pitzolis G. 1979. Observations on breeding sites and light-trap collections of Culicoides during an outbreak of bluetongue in Cyprus. Bull. Entomol. Res. 69:229-234.
49. Mirchamsy H, Hazrati A. 1973. A review of the aetiology and pathology of African horsesickness. Arch. Hessarek Iran 25:23-46.
50. Naitow H, Tang J, Canady M, Wickner RB, Johnson JE. 2002. L-A virus at 3.4 Å resolution reveals particle architecture and mRNA decapping mechanism. Nat. Struct. Biol. 9:725-728.
51. Nason EL, et al. 2004. Interactions between the inner and outer capsids of bluetongue virus. J. Virol. 78:8059-8067.
52. Needleman SB, Wunsch CD. 1970. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 48:443-453.
53. Oellermann RA. 1970. Plaque formation by African horsesickness virus and characterization of its RNA. Onderstepoort J. Vet. Res. 37:137-143.
54. Pettersen EF, et al. 2004. UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25:1605-1612.
55. Potgieter AC, et al. 2009. Improved strategies for sequence-independent amplification and sequencing of viral double-stranded RNA genomes. J. Gen. Virol. 90:1423-1432.
56. Purse BV, et al. 2005. Climate change and the recent emergence of bluetongue in Europe. Nat. Rev. Microbiol. 3:171-181.
57. Rafyi A. 1961. Horse sickness. Bull. Off. Int. Epizoot. 56:216-250.
58. Reinisch KM, Nibert ML, Harrison SC. 2000. Structure of the reovirus core at 3.6 Å resolution. Nature 404:960-967.
59. Roy A, Kucukural A, Zhang Y. 2010. I-TASSER: a unified platform for automated protein structure and function prediction. Nat. Protoc. 5:725-738.
60. Roy P, Bishop DH, Howard S, Aitchison H, Erasmus B. 1996. Recombinant baculovirus-synthesized African horsesickness virus (AHSV) outer-capsid protein VP2 provides protection against virulent AHSV challenge. J. Gen. Virol. 77:2053-2057.
61. Roy P, Mertens PP, Casal I. 1994. African horsesickness virus structure. Comp. Immunol. Microbiol. Infect. Dis. 17:243-273.
62. Scanlen M, Paweska JT, Verschoor JA, van Dijk AA. 2002. The protective efficacy of a recombinant VP2-based African horsesickness subunit vaccine candidate is determined by adjuvant. Vaccine 20:1079-1088.
63. Seitsonen J, et al. 2010. Interaction of alphaVbeta3 and alphaVbeta6 integrins with human parechovirus 1. J. Virol. 84:8509-8519.
64. Stone-Marschat MA, et al. 1996. Immunization with VP2 is sufficient for protection against lethal challenge with African horsesickness virus type 4. Virology 220:219-222.
65. Theiler A. 1921. African horse sickness (pestis equorum). South Afr. Dept. Agric. Sci. Bull. 19:30.
66. Thiry E, et al. 2006. Bluetongue in northern Europe. Vet. Rec. 159:327.
67. van Staden V, Huismans H. 1991. A comparison of the genes which encode non-structural protein NS3 of different orbiviruses. J. Gen. Virol. 72:1073-1079.
68. van Staden V, Theron J, Greyling BJ, Huismans H, Nel LH. 1991. A comparison of the nucleotide sequences of cognate NS2 genes of three different orbiviruses. Virology 185:500-504.
69. Venter GJ, Wright IM, Van Der Linde TC, Paweska JT. 2009. The oral susceptibility of South African field populations of Culicoides to African horsesickness virus. Med. Vet. Entomol. 23:367-378.
70. Wilson A, Mellor PS, Szmaragd C, Mertens PP. 2009. Adaptive strategies of African horsesickness virus to facilitate vector transmission. Vet. Res. 40:16.
71. Yan X, Sinkovits RS, Baker TS. 2007. AUTO3DEM-an automated and high throughput program for image reconstruction of icosahedral particles. J. Struct. Biol. 157:73-82.
72. Zhang X, et al. 2010. Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins. Proc. Natl. Acad. Sci. U. S. A. 107:6292-6297.
73. Zhang X, et al. 2008. Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. Proc. Natl. Acad. Sci. U. S. A. 105:1867-1872.
74. Zhang Y. 2008. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics 9:40. doi:10.1186/1471-2105-9-40.