USP1 regulates AKT phosphorylation by modulating the stability of PHLPP1 in lung cancer cells

Journal of Cancer Research and Clinical Oncology

Volumn 138, Issue 7, 2012, Pages 1231-1238

  Zhang, Zhiqiang ^a   Qinghui, Yang ^a   Zhang, Yongqiang ^a   Zhang, Jian ^a   Xin, Zhao ^a   Haiying, Ma ^a   Yuepeng, Guo ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

AKT phosphorylation deubiquitination; Lung cancer; PHLPP1; USP1

Indexed keywords

MESSENGER RNA; PEPTIDASE; PH DOMAIN LEUCINE RICH PROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE; UBIQUITIN SPECIFIC PEPTIDASE 1; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

CELL DEATH; CELL LINE, TUMOR; ENDOPEPTIDASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; UBIQUITINATION;

EID: 84864355390     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1193-3     Document Type: Article

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