Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells

Genes to Cells

Volumn 17, Issue 8, 2012, Pages 720-727

  Yachi, Rieko ^a   Uchida, Yasunori ^a   Balakrishna, Bhat Hema ^b   Anderluh, Gregor ^c,d   Kobayashi, Toshihide ^b   Taguchi, Tomohiko ^a   Arai, Hiroyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b RIKEN   (Japan)

^c NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^d UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

EQUINATOXIN II; LYSENIN; PROTEIN; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN SYNTHASE 1; SPHINGOMYELIN SYNTHASE 2; TOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; ENDOSOME; GENE SILENCING; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS;

ANIMALS; BRIDGED COMPOUNDS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CNIDARIAN VENOMS; COS CELLS; MEMBRANE PROTEINS; RNA, SMALL INTERFERING; SPHINGOMYELINS; STAINING AND LABELING; THIONES; TOXINS, BIOLOGICAL; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

CERCOPITHECUS AETHIOPS; MAMMALIA;

EID: 84864301066     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2012.01621.x     Document Type: Article

References (23)

1. Abe, M., Makino, A., Hullin-Matsuda, F., Kamijo, K., Ohno-Iwashita, Y., Hanada, K., Mizuno, H., Miyawaki, A. & Kobayashi, T. (2012) A role for sphingomyelin-rich lipid domains in the accumulation of phosphatidylinositol-4, 5-bisphosphate to the cleavage furrow during cytokinesis. Mol. Cell. Biol. 32, 1396-1407.
2. Bakrac, B., Gutierrez-Aguirre, I., Podlesek, Z., Sonnen, A.F., Gilbert, R.J., Macek, P., Lakey, J.H. & Anderluh, G. (2008) Molecular determinants of sphingomyelin specificity of a eukaryotic pore-forming toxin. J. Biol. Chem. 283, 18665-18677.
3. Bakrac, B., Kladnik, A., Macek, P., McHaffie, G., Werner, A., Lakey, J.H. & Anderluh, G. (2010) A toxin-based probe reveals cytoplasmic exposure of Golgi sphingomyelin. J. Biol. Chem. 285, 22186-22195.
4. Barlic, A., Gutierrez-Aguirre, I., Caaveiro, J.M., Cruz, A., Ruiz-Arguello, M.B., Perez-Gil, J. & Gonzalez-Manas, J.M. (2004) Lipid phase coexistence favors membrane insertion of equinatoxin-II, a pore-forming toxin from Actinia equina. J. Biol. Chem. 279, 34209-34216.
5. Gagescu, R., Demaurex, N., Parton, R.G., Hunziker, W., Huber, L.A. & Gruenberg, J. (2000) The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components. Mol. Biol. Cell 11, 2775-2791.
6. Gonzalez-Roura, A., Casas, J. & Llebaria, A. (2002) Synthesis and phospholipase C inhibitory activity of D609 diastereomers. Lipids 37, 401-406.
7. Hanada, K., Kumagai, K., Yasuda, S., Miura, Y., Kawano, M., Fukasawa, M. & Nishijima, M. (2003) Molecular machinery for non-vesicular trafficking of ceramide. Nature 426, 803-809.
8. Hannun, Y.A. & Obeid, L.M. (2008) Principles of bioactive lipid signalling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9, 139-150.
9. Huitema, K., van den Dikkenberg, J., Brouwers, J.F. & Holthuis, J.C. (2004) Identification of a family of animal sphingomyelin synthases. EMBO J. 23, 33-44.
10. Ishitsuka, R., Yamaji-Hasegawa, A., Makino, A., Hirabayashi, Y. & Kobayashi, T. (2004) A lipid-specific toxin reveals heterogeneity of sphingomyelin-containing membranes. Biophys. J. 86, 296-307.
11. Keenan, T.W. & Morre, D.J. (1970) Phospholipid class and fatty acid composition of golgi apparatus isolated from rat liver and comparison with other cell fractions. Biochemistry 9, 19-25.
12. Kidani, Y., Ohshima, K., Sakai, H., Kohno, T., Baba, A. & Hattori, M. (2012) Differential localization of sphingomyelin synthase isoforms in neurons regulates sphingomyelin cluster formation. Biochem. Biophys. Res. Commun. 417, 1014-1017.
13. Lajoie, P., Goetz, J.G., Dennis, J.W. & Nabi, I.R. (2009) Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J. Cell Biol. 185, 381-385.
14. Lingwood, D. & Simons, K. (2010) Lipid rafts as a membrane-organizing principle. Science 327, 46-50.
15. Meng, A., Luberto, C., Meier, P., Bai, A., Yang, X., Hannun, Y.A. & Zhou, D. (2004) Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells. Exp. Cell Res. 292, 385-392.
16. Misaki, R., Nakagawa, T., Fukuda, M., Taniguchi, N. & Taguchi, T. (2007) Spatial segregation of degradation- and recycling-trafficking pathways in COS-1 cells. Biochem. Biophys. Res. Commun. 360, 580-585.
17. Paulick, M.G. & Bertozzi, C.R. (2008) The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry 47, 6991-7000.
18. Prior, I.A., Muncke, C., Parton, R.G. & Hancock, J.F. (2003) Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J. Cell Biol. 160, 165-170.
19. Schon, P., Garcia-Saez, A.J., Malovrh, P., Bacia, K., Anderluh, G. & Schwille, P. (2008) Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence. Biophys. J. 95, 691-698.
20. Spessott, W., Uliana, A. & Maccioni, H.J. (2010) Cog2 null mutant CHO cells show defective sphingomyelin synthesis. J. Biol. Chem. 285, 41472-41482.
21. Tafesse, F.G., Huitema, K., Hermansson, M., van der Poel, S., van den Dikkenberg, J., Uphoff, A., Somerharju, P. & Holthuis, J.C. (2007) Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells. J. Biol. Chem. 282, 17537-17547.
22. Yamaji, A., Sekizawa, Y., Emoto, K., Sakuraba, H., Inoue, K., Kobayashi, H. & Umeda, M. (1998) Lysenin, a novel sphingomyelin-specific binding protein. J. Biol. Chem. 273, 5300-5306.
23. Yamaoka, S., Miyaji, M., Kitano, T., Umehara, H. & Okazaki, T. (2004) Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells. J. Biol. Chem. 279, 18688-18693.