Structured three-dimensional co-culture of mesenchymal stem cells with meniscus cells promotes meniscal phenotype without hypertrophy

Biotechnology and Bioengineering

Volumn 109, Issue 9, 2012, Pages 2369-2380

  Cui, Xiaofeng ^a,b   Hasegawa, Akihiko ^a   Lotz, Martin ^a   D'Lima, Darryl ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SCRIPPS CLINIC   (United States)

Author keywords

Extracellular matrix; Fibrochondrocyte; Hypertrophy; Meniscus tissue engineering; Mesenchymal stem cells

Indexed keywords

ARTICULAR CARTILAGES; CELL PELLETS; CHONDROGENIC; CLINICAL TREATMENTS; CO-CULTURES; COCULTURE; COLLAGEN FIBER; COLLAGEN TYPE I; DIFFERENTIATED CELLS; EXTRACELLULAR MATRICES; FIBROCHONDROCYTE; GLYCOSAMINOGLYCANS; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; KNEE JOINT; LOAD BEARING; MECHANICAL STRESS; MENISCECTOMIES; MESENCHYMAL STEM CELL; PROTEOGLYCANS; SHOCK ABSORPTION; TRANSFORMING GROWTH FACTOR BETA; WEIGHT DISTRIBUTIONS;

CARTILAGE; CELLS; COLLAGEN; ENZYME INHIBITION; GENE EXPRESSION; JOINTS (ANATOMY); PATHOLOGY; PELLETIZING; STRESSES; TISSUE; TISSUE ENGINEERING;

CELL CULTURE;

COLLAGEN; COLLAGEN FIBER; COLLAGEN TYPE 1; GLYCOSAMINOGLYCAN; PROTEOGLYCAN; TRANSFORMING GROWTH FACTOR BETA3;

ARTICLE; CELL CULTURE; CELL STRUCTURE; CHEMICAL ANALYSIS; COCULTURE; COL10A1 GENE; COLLAGENASE 3 GENE; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MENISCAL CELL; MESENCHYMAL STEM CELL; PHENOTYPE; TISSUE ENGINEERING;

CELLS, CULTURED; COCULTURE TECHNIQUES; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION; HUMANS; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MENISCI, TIBIAL; MESENCHYMAL STROMAL CELLS; PARTICLE SIZE; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA;

EID: 84864299759     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24495     Document Type: Article

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