Scutellarin inhibits cytochrome P450 isoenzyme 1A2 (CYP1A2) in rats

Phytotherapy Research

Volumn 26, Issue 8, 2012, Pages 1226-1230

  Jian, Tun Yu ^a,b   He, Jian Chang ^a   He, Gong Hao ^a   Feng, En Fu ^a   Li, Hong Liang ^a,b   Bai, Min ^a,b   Xu, Gui Li ^a,b  

^a KUNMING GENERAL HOSPITAL   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

CYP1A2; phenacetin; rat liver microsomes; scutellarin

Indexed keywords

CYTOCHROME P450 1A2; PARACETAMOL; PHENACETIN; SCUTELLARIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE COMPARISON; DRUG HALF LIFE; DRUG METABOLISM; ENZYME INHIBITION; FEMALE; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; SINGLE DRUG DOSE;

ANIMALS; APIGENIN; AREA UNDER CURVE; CYTOCHROMES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; ERIGERON; FEMALE; GLUCURONATES; INHIBITORY CONCENTRATION 50; LIVER; MALE; MICROSOMES, LIVER; PHENACETIN; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

ANIMALIA; ERIGERON BREVISCAPUS; RATTUS;

EID: 84864279610     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3723     Document Type: Article

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