A neuronal transmembrane protein LRFN4 complexes with 14-3-3s and NCK1 to induce morphological change in monocytic cells via Rac1-mediated actin cytoskeleton reorganization

FEBS Letters

Volumn 586, Issue 16, 2012, Pages 2251-2259

  Konakahara, Shu ^a   Suzuki, Yuki ^a   Kawakami, Takao ^b,c   Saitou, Maki ^a   Kajikawa, Masunori ^d   Masuho, Yasuhiko ^a   Kohroki, Junya ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c Yokohama Bio Industry Center   (Japan)

^d ACTGen Inc   (Japan)

Author keywords

14 3 3; Actin cytoskeleton reorganization; Cell migration; Leucine rich repeat protein; Monocytic cells; Morphological change; NCK1; Rac1

Indexed keywords

ADAPTOR PROTEIN; LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 4 PROTEIN; MEMBRANE PROTEIN; PROTEIN 14 3 3; PROTEIN NCK1; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; BINDING SITE; CELL ELONGATION; CELL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; LAMELLIPODIUM; MONOCYTE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL MEMBRANE; CYTOPLASM; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HELA CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MONOCYTES; NERVE TISSUE PROTEINS; NEURONS; ONCOGENE PROTEINS; PROTEIN BINDING; PROTEIN ISOFORMS; RAC1 GTP-BINDING PROTEIN;

EID: 84864278070     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.05.053     Document Type: Article

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