Retigeric acid B attenuates the virulence of candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Chang, Wenqiang ^a   Li, Ying ^a   Zhang, Li ^a   Cheng, Aixia ^a   Lou, Hongxiang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADHESIN; ANTIFUNGAL AGENT; CELL PROTEIN; CYCLIC AMP; FARNESOL; FLUCONAZOLE; PROTEIN CDC35; PROTEIN DPP3; PROTEIN EFG1; RAS1 PROTEIN; RETIGERIC ACID B; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CAENORHABDITIS ELEGANS; CANDIDA ALBICANS; CANDIDIASIS; CELL LEVEL; CELL TRANSFORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FUNGAL PHENOMENA AND FUNCTIONS; FUNGAL STRUCTURES; FUNGAL VIRULENCE; FUNGUS HYPHAE; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MASS FRAGMENTOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; MORPHOLOGIC TRANSITION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; YEAST TO HYPHAL TRANSITION;

ADENYLATE CYCLASE; ANIMALS; ANTIFUNGAL AGENTS; CAENORHABDITIS ELEGANS; CANDIDA ALBICANS; CYCLIC AMP; DNA-BINDING PROTEINS; FARNESOL; FUNGAL PROTEINS; HYPHAE; INTRACELLULAR SPACE; RAS PROTEINS; TRANSCRIPTION FACTORS; TRITERPENES;

CANDIDA ALBICANS; NEMATODA;

EID: 84864257452     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041624     Document Type: Article

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