Signal transduction using an artificial receptor system that undergoes dimerization upon addition of a bivalent leucine-zipper ligand

Angewandte Chemie - International Edition

Volumn 51, Issue 30, 2012, Pages 7464-7467

  Nakase, Ikuhiko ^a   Okumura, Shinya ^a   Tanaka, Gen ^a   Osaki, Katsuhiro ^a   Imanishi, Miki ^a   Futaki, Shiroh ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

epidermal growth factor; leucine zipper peptides; protein protein interactions; receptor dimerization; receptors

Indexed keywords

ARTIFICIAL RECEPTORS; CYTOPLASMIC DOMAINS; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL GROWTH FACTORS; EXTRACELLULAR; PROTEIN-PROTEIN INTERACTIONS; RECEPTORS; SIGNALING CASCADES; TRANSMEMBRANES;

DIMERIZATION; LIGANDS; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACIDS;

EPIDERMAL GROWTH FACTOR RECEPTOR; LEUCINE ZIPPER PROTEIN; LIGAND; PEPTIDE;

ANIMAL; ARTICLE; CELL MOTION; CHEMISTRY; CHO CELL; GENE EXPRESSION; GENETICS; HAMSTER; METABOLISM; PROTEIN ANALYSIS; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; CHO CELLS; CRICETINAE; GENE EXPRESSION; LEUCINE ZIPPERS; LIGANDS; PEPTIDES; PROTEIN INTERACTION MAPPING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84864255691     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201201805     Document Type: Article

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