The complex actions of sumatriptan on rat dural afferents

Cephalalgia

Volumn 32, Issue 10, 2012, Pages 738-749

  Harriott, Andrea M ^a,b   Scheff, Nicole N ^b   Gold, Michael S ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

current clamp; in vitro; Nociceptor sensitization; patch clamp

Indexed keywords

BRADYKININ; HISTAMINE; POTASSIUM CHANNEL; PROSTAGLANDIN E2; SUMATRIPTAN; TRIPTAN DERIVATIVE; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CHLORIDE CURRENT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DURA MATER; IN VITRO STUDY; INFLAMMATION; MIGRAINE; NOCICEPTION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RAT; SENSITIZATION; SENSORY NERVE; SODIUM CURRENT;

ANIMALS; CALCIUM CHANNELS; DURA MATER; FEMALE; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SUMATRIPTAN;

EID: 84864243367     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102412451356     Document Type: Article

References (42)

1. Lipton RB, Stewart WF, Scher AI. Epidemiology and economic impact of migraine. Curr Med Res Opin. 2001 ; 17 (Suppl 1). s4 - s12
2. Galletti F, Cupini LM, Corbelli I, Calabresi P, Sarchielli P. Pathophysiological basis of migraine prophylaxis. Prog Neurobiol. 2009 ; 89: 176-192
3. Tfelt-Hansen P, De Vries P, Saxena PR. Triptans in migraine: a comparative review of pharmacology, pharmacokinetics and efficacy. Drugs. 2000 ; 60: 1259-1287
4. Sarchielli P, Alberti A, Codini M, Floridi A, Gallai V. Nitric oxide metabolites, prostaglandins and trigeminal vasoactive peptides in internal jugular vein blood during spontaneous migraine attacks. Cephalalgia. 2000 ; 20: 907-918
5. Strassman AM, Raymond SA, Burstein R. Sensitization of meningeal sensory neurons and the origin of headaches. Nature. 1996 ; 384: 560-564
6. Harriott AM, Gold MS. Electrophysiological properties of dural afferents in the absence and presence of inflammatory mediators. J Neurophysiol. 2009 ; 101: 3126-3134
7. Vaughn AH, Gold MS. Ionic mechanisms underlying inflammatory mediator-induced sensitization of dural afferents. J Neurosci. 2010 ; 30: 7878-7888
8. Harriott AM, Gold MS. Serotonin type 1D receptors (5HTR) are differentially distributed in nerve fibres innervating craniofacial tissues. Cephalalgia. 2008 ; 28: 933-944
9. Potrebic S, Ahn AH, Skinner K, Fields HL, Basbaum AI. Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans. J Neurosci. 2003 ; 23: 10988-10997
10. Dao TT, Lund JP, Remillard G, Lavigne GJ. Is myofascial pain of the temporal muscles relieved by oral sumatriptan? A cross-over pilot study. Pain. 1995 ; 62: 241-244
11. Pierce PA, Xie GX, Peroutka SJ, Levine JD. Dual effect of the serotonin agonist, sumatriptan, on peripheral neurogenic inflammation. Reg Anesth. 1996 ; 21: 219-225
12. Nikai T, Basbaum AI, Ahn AH. Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan. Pain. 2008 ; 139: 533-540
13. Vera-Portocarrero LP, Ossipov MH, King T, Porreca F. Reversal of inflammatory and noninflammatory visceral pain by central or peripheral actions of sumatriptan. Gastroenterology. 2008 ; 135: 1369-1378
14. Ottani A, Ferraris E, Giuliani D, Mioni C, Bertolini A, Sternieri E, Ferrari A. Effect of sumatriptan in different models of pain in rats. Eur J Pharmacol. 2004 ; 497: 181-186
15. Kayser V, Aubel B, Hamon M, Bourgoin S. The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain. Br J Pharmacol. 2002 ; 137: 1287-1297
16. Cumberbatch MJ, Hill RG, Hargreaves RJ. Differential effects of the 5HT1B/1D receptor agonist naratriptan on trigeminal versus spinal nociceptive responses. Cephalalgia. 1998 ; 18: 659-663
17. Morikawa T, Matsuzawa Y, Makita K, Katayama Y. Antimigraine drug, zolmitriptan, inhibits high-voltage activated calcium currents in a population of acutely dissociated rat trigeminal sensory neurons. Mol Pain. 2006 ; 2: 10-10
18. 2+ channels. J Neurosci. 1999 ; 19: 890-899
19. Ikeda SR. Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits. Nature. 1996 ; 380: 255-258
20. Jiang M, Gold MS, Boulay G, Spicher K, Peyton M, Brabet P, et al. Multiple neurological abnormalities in mice deficient in the G protein Go. Proc Natl Acad Sci U S A. 1998 ; 95: 3269-3274
21. Fox AW. Onset of effect of 5-HT1B/1D agonists: a model with pharmacokinetic validation. Headache. 2004 ; 44: 142-147
22. Pilgrim AJ. The clinical profile of sumatriptan: efficacy in migraine. Eur Neurol. 1994 ; 34 (Suppl 2): 26-34
23. Akaike N. Gramicidin perforated patch recording and intracellular chloride activity in excitable cells. Prog Biophys Mol Biol. 1996 ; 65: 251-264
24. Evans MS, Cheng X, Jeffry JA, Disney KE, Premkumar LS. Sumatriptan inhibits TRPV1 channels in trigeminal neurons. Headache. 2012 ; 52: 773-784
25. Burstein R, Jakubowski M, Levy D. Anti-migraine action of triptans is preceded by transient aggravation of headache caused by activation of meningeal nociceptors. Pain. 2005 ; 115: 21-28
26. Strassman AM, Levy D. The anti-migraine agent sumatriptan induces a calcium-dependent discharge in meningeal sensory neurons. Neuroreport. 2004 ; 15: 1409-1412
27. Gold MS, Shuster MJ, Levine JD. Characterization of six voltage-gated K+ currents in adult rat sensory neurons. J Neurophysiol. 1996 ; 75: 2629-2646
28. Zhang XL, Mok LP, Katz EJ, Gold MS. BK(Ca) currents are enriched in a subpopulation of adult rat cutaneous nociceptive dorsal root ganglion neurons. Eur J Neurosci. 2010 ; 31: 450-462
29. Zhang X-L, Mok L, Charbonnet M, Lee K-Y, Gold MS. Inflammation-induced changes in BKCa currents in cutaneous dorsal root ganglion neurons from the adult rat. Mol Pain 2012; 8(1): 37.
30. Bocksteins E, Raes AL, Van de Vijver G, Bruyns T, Van Bogaert PP, Snyders DJ. Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons. Am J Physiol Cell Physiol. 2009 ; 296: C1271 - C1278
31. Park KS, Mohapatra DP, Misonou H, Trimmer JS. Graded regulation of the Kv2.1 potassium channel by variable phosphorylation. Science. 2006 ; 313: 976-979
32. Nicholson R, Small J, Dixon AK, Spanswick D, Lee K. Serotonin receptor mRNA expression in rat dorsal root ganglion neurons. Neurosci Lett. 2003 ; 337: 119-122
33. Hou M, Kanje M, Longmore J, Tajti J, Uddman R, Edvinsson L. 5-HT(1B) and 5-HT(1D) receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase. Brain Res. 2001 ; 909: 112-120
34. Razzaque Z, Pickard JD, Ma QP, Shaw D, Morrison K, Wang T, Longmore J. 5-HT1B-receptors and vascular reactivity in human isolated blood vessels: assessment of the potential craniovascular selectivity of sumatriptan. Br J Clin Pharmacol. 2002 ; 53: 266-274
35. Donaldson C, Boers PM, Hoskin KL, Zagami AS, Lambert GA. The role of 5-HT1B and 5-HT1D receptors in the selective inhibitory effect of naratriptan on trigeminovascular neurons. Neuropharmacology. 2002 ; 42: 374-385
36. Levy D, Jakubowski M, Burstein R. Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists. Proc Natl Acad Sci U S A. 2004 ; 101: 4274-4279
37. Zamponi GW, Lewis RJ, Todorovic SM, Arneric SP, Snutch TP. Role of voltage-gated calcium channels in ascending pain pathways. Brain Res Rev. 2009 ; 60: 84-89
38. 2+ current in the action potentials of nociceptive sensory neurons. J Neurosci. 2002 ; 22: 10277-10290
39. Czirjak G, Enyedi P. TRESK background K(+) channel is inhibited by phosphorylation via two distinct pathways. J Biol Chem. 2010 ; 285: 14549-14557
40. 2+ channels. J Neurosci. 1995 ; 15: 4124-4132
41. Sanderson TM, Collingridge GL, Fitzjohn SM. Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs. Mol Brain. 2011 ; 4: 30-30
42. Goadsby PJ, Sprenger T. Current practice and future directions in the prevention and acute management of migraine. Lancet Neurol. 2010 ; 9: 285-298