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Volumn 7, Issue 7, 2012, Pages

Identifying novel drug indications through automated reasoning

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DIPYRIDAMOLE; ERLOTINIB; LEVODOPA; MOCLOBEMIDE; TAZAROTENE;

EID: 84864238297     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040946     Document Type: Article
Times cited : (18)

References (33)
  • 1
    • 0037374498 scopus 로고    scopus 로고
    • The price of innovation: new estimates of drug development costs
    • 10.1016/S0167-6296(02)00126-1
    • DiMasi JA, Hansen RW, Grabowski HG, (2003) The price of innovation: new estimates of drug development costs. Journal of Health Economics 22: 151-185 doi:10.1016/S0167-6296(02)00126-1.
    • (2003) Journal of Health Economics , vol.22 , pp. 151-185
    • DiMasi, J.A.1    Hansen, R.W.2    Grabowski, H.G.3
  • 2
    • 4344668661 scopus 로고    scopus 로고
    • Drug repositioning: identifying and developing new uses for existing drugs
    • 10.1038/nrd1468
    • Ashburn TT, Thor KB, (2004) Drug repositioning: identifying and developing new uses for existing drugs. Nature Reviews Drug Discovery 3: 673-683 doi:10.1038/nrd1468.
    • (2004) Nature Reviews Drug Discovery , vol.3 , pp. 673-683
    • Ashburn, T.T.1    Thor, K.B.2
  • 3
    • 33746584053 scopus 로고    scopus 로고
    • Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond
    • 10.1038/nrd2030
    • Ghofrani HA, Osterloh IH, Grimminger F, (2006) Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond. Nature Reviews Drug Discovery 5: 689-702 doi:10.1038/nrd2030.
    • (2006) Nature Reviews Drug Discovery , vol.5 , pp. 689-702
    • Ghofrani, H.A.1    Osterloh, I.H.2    Grimminger, F.3
  • 4
    • 77953387346 scopus 로고    scopus 로고
    • Drug repositioning using in silico compound profiling
    • 10.4155/fmc.09.123
    • Dubus E, Ijjaali I, Barberan O, Petitet F, (2009) Drug repositioning using in silico compound profiling. Future Medicinal Chemistry 1: 1723-1736 doi:10.4155/fmc.09.123.
    • (2009) Future Medicinal Chemistry , vol.1 , pp. 1723-1736
    • Dubus, E.1    Ijjaali, I.2    Barberan, O.3    Petitet, F.4
  • 8
    • 0037545622 scopus 로고    scopus 로고
    • Generating hypotheses by discovering implicit associations in the literature: a case report of a search for new potential therapeutic uses for thalidomide
    • 10.1197/jamia.M1158
    • Weeber M, Vos R, Klein H, De Jong-Van Den Berg LTW, Aronson AR, et al. (2003) Generating hypotheses by discovering implicit associations in the literature: a case report of a search for new potential therapeutic uses for thalidomide. Journal of the American Medical Informatics Association 10: 252-259 doi:10.1197/jamia.M1158.
    • (2003) Journal of the American Medical Informatics Association , vol.10 , pp. 252-259
    • Weeber, M.1    Vos, R.2    Klein, H.3    de Jong-Van Den Berg, L.T.W.4    Aronson, A.R.5
  • 9
    • 33750742458 scopus 로고    scopus 로고
    • Using statistical and knowledge-based approaches for literature-based discovery
    • 10.1016/j.jbi.2005.11.010
    • Yetisgen-Yildiz M, Pratt W, (2006) Using statistical and knowledge-based approaches for literature-based discovery. Journal of Biomedical informatics 39: 600-611 doi:10.1016/j.jbi.2005.11.010.
    • (2006) Journal of Biomedical Informatics , vol.39 , pp. 600-611
    • Yetisgen-Yildiz, M.1    Pratt, W.2
  • 12
    • 44349084276 scopus 로고    scopus 로고
    • IDMap: facilitating the detection of potential leads with therapeutic targets
    • 10.1093/bioinformatics/btn138
    • Ha S, Seo Y-J, Kwon M-S, Chang B-H, Han C-K, et al. (2008) IDMap: facilitating the detection of potential leads with therapeutic targets. Bioinformatics 24: 1413-1415 doi:10.1093/bioinformatics/btn138.
    • (2008) Bioinformatics , vol.24 , pp. 1413-1415
    • Ha, S.1    Seo, Y.-J.2    Kwon, M.-S.3    Chang, B.-H.4    Han, C.-K.5
  • 13
    • 79960766975 scopus 로고    scopus 로고
    • Literature mining, ontologies and information visualization for drug repurposing
    • 10.1093/bib/bbr005
    • Andronis C, Sharma A, Virvilis V, Deftereos S, Persidis A, (2011) Literature mining, ontologies and information visualization for drug repurposing. Briefings in Bioinformatics 12: 357-368 doi:10.1093/bib/bbr005.
    • (2011) Briefings in Bioinformatics , vol.12 , pp. 357-368
    • Andronis, C.1    Sharma, A.2    Virvilis, V.3    Deftereos, S.4    Persidis, A.5
  • 14
    • 57349093766 scopus 로고    scopus 로고
    • Levodopa for the treatment of Parkinson's disease
    • 10.1056/NEJMct0800326
    • Lewitt PA, (2008) Levodopa for the treatment of Parkinson's disease. The New England Journal of Medicine 359: 2468-2476 doi:10.1056/NEJMct0800326.
    • (2008) The New England Journal of Medicine , vol.359 , pp. 2468-2476
    • Lewitt, P.A.1
  • 15
    • 33645217263 scopus 로고    scopus 로고
    • EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization
    • 10.1007/s10549-005-9011-0
    • Lo H-W, Hsu S-C, Hung M-C, (2006) EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Research and Treatment 95: 211-218 doi:10.1007/s10549-005-9011-0.
    • (2006) Breast Cancer Research and Treatment , vol.95 , pp. 211-218
    • Lo, H.-W.1    Hsu, S.-C.2    Hung, M.-C.3
  • 16
    • 33644876210 scopus 로고    scopus 로고
    • DrugBank: a comprehensive resource for in silico drug discovery and exploration
    • 10.1093/nar/gkj067
    • Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, et al. (2006) DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic acids research 34: D668-72 doi:10.1093/nar/gkj067.
    • (2006) Nucleic Acids Research , vol.34
    • Wishart, D.S.1    Knox, C.2    Guo, A.C.3    Shrivastava, S.4    Hassanali, M.5
  • 17
    • 0035755351 scopus 로고    scopus 로고
    • Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base
    • Klein TE, Chang JT, Cho MK, Easton KL, Fergerson R, et al. (2001) Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. The Pharmacogenomics Journal 1: 167-170.
    • (2001) The Pharmacogenomics Journal , vol.1 , pp. 167-170
    • Klein, T.E.1    Chang, J.T.2    Cho, M.K.3    Easton, K.L.4    Fergerson, R.5
  • 21
    • 40549140499 scopus 로고    scopus 로고
    • BANNER: an executable survey of advances in biomedical named entity recognition
    • Leaman R, Gonzalez G, (2008) BANNER: an executable survey of advances in biomedical named entity recognition. Pacific Symposium on Biocomputing pp. 652-663.
    • (2008) Pacific Symposium on Biocomputing , pp. 652-663
    • Leaman, R.1    Gonzalez, G.2
  • 22
    • 49549120418 scopus 로고    scopus 로고
    • Inter-species normalization of gene mentions with GNAT
    • 10.1093/bioinformatics/btn299
    • Hakenberg J, Plake C, Leaman R, Schroeder M, Gonzalez G, (2008) Inter-species normalization of gene mentions with GNAT. Bioinformatics 24: i126-132 doi:10.1093/bioinformatics/btn299.
    • (2008) Bioinformatics , vol.24
    • Hakenberg, J.1    Plake, C.2    Leaman, R.3    Schroeder, M.4    Gonzalez, G.5
  • 24
    • 77951505493 scopus 로고
    • Classical Negation in Logic Programs and Disjunctive Databases
    • Gelfond M, Lifschitz V, (1991) Classical Negation in Logic Programs and Disjunctive Databases. New Generation Computing pp. 365-387.
    • (1991) New Generation Computing , pp. 365-387
    • Gelfond, M.1    Lifschitz, V.2
  • 27
    • 85020443875 scopus 로고    scopus 로고
    • Phase I Study of Disulfiram, Copper Gluconate for the Treatment of Refractory Solid Tumors Involving the Liver
    • Phase I Study of Disulfiram, Copper Gluconate for the Treatment of Refractory Solid Tumors Involving the Liver, (2008) Available http://clinicaltrials.gov/ct2/show/NCT00742911.
    • (2008)
  • 28
    • 84875372834 scopus 로고    scopus 로고
    • Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer
    • Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer, Basal Cell Nevus Syndrome on the Chest, Back (2008) Available http://clinicaltrials.gov/ct2/show/NCT00783965.
    • (2008) Basal Cell Nevus Syndrome on the Chest
  • 29
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • 10.1038/nature01322
    • Coussens LM, Werb Z, (2002) Inflammation and cancer. Nature 420: 860-867 doi:10.1038/nature01322.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 30
    • 43749110484 scopus 로고    scopus 로고
    • Extraction of semantic biomedical relations from text using conditional random fields
    • 10.1186/1471-2105-9-207
    • Bundschus M, Dejori M, Stetter M, Tresp V, Kriegel H-P, (2008) Extraction of semantic biomedical relations from text using conditional random fields. BMC Bioinformatics 9: 207 doi:10.1186/1471-2105-9-207.
    • (2008) BMC Bioinformatics , vol.9 , pp. 207
    • Bundschus, M.1    Dejori, M.2    Stetter, M.3    Tresp, V.4    Kriegel, H.-P.5
  • 31
    • 33847608309 scopus 로고    scopus 로고
    • BioInfer: a corpus for information extraction in the biomedical domain
    • 10.1186/1471-2105-8-50
    • Pyysalo S, Ginter F, Heimonen J, Björne J, Boberg J, et al. (2007) BioInfer: a corpus for information extraction in the biomedical domain. BMC Bioinformatics 8: 50 doi:10.1186/1471-2105-8-50.
    • (2007) BMC Bioinformatics , vol.8 , pp. 50
    • Pyysalo, S.1    Ginter, F.2    Heimonen, J.3    Björne, J.4    Boberg, J.5
  • 32
    • 84873040259 scopus 로고    scopus 로고
    • Synthesis of pharmacokinetic pathways through knowledge acquisition and automated reasoning
    • Tari L, Anwar S, Liang S, Hakenberg J, Baral C, (2010) Synthesis of pharmacokinetic pathways through knowledge acquisition and automated reasoning. Pacific Symposium on Biocomputing. Vol. 476: 465-476.
    • (2010) Pacific Symposium on Biocomputing , vol.476 , pp. 465-476
    • Tari, L.1    Anwar, S.2    Liang, S.3    Hakenberg, J.4    Baral, C.5
  • 33
    • 77956517407 scopus 로고    scopus 로고
    • Discovering drug-drug interactions: a text-mining and reasoning approach based on properties of drug metabolism
    • 10.1093/bioinformatics/btq382
    • Tari L, Anwar S, Liang S, Cai J, Baral C, (2010) Discovering drug-drug interactions: a text-mining and reasoning approach based on properties of drug metabolism. Bioinformatics 26: i547-53 doi:10.1093/bioinformatics/btq382.
    • (2010) Bioinformatics , vol.26
    • Tari, L.1    Anwar, S.2    Liang, S.3    Cai, J.4    Baral, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.