Early cerebral perfusion pressure augmentation with phenylephrine after traumatic brain injury may be neuroprotective in a pediatric swine model

Critical Care Medicine

Volumn 40, Issue 8, 2012, Pages 2400-2406

  Friess, Stuart H ^a   Smith, Colin ^c   Kilbaugh, Todd J ^a   Frangos, Suzanne G ^a   Ralston, Jill ^b   Helfaer, Mark A ^a   Margulies, Susan S ^b,d  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

cerebral blood flow; cerebral perfusion pressure; neuroprotection; pediatric head injury; phenylephrine; swine

Indexed keywords

LACTIC ACID; PHENYLEPHRINE; PYRUVIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN PERFUSION; BRAIN TISSUE; CELL DAMAGE; CEREBRAL PERFUSION PRESSURE; CONTROLLED STUDY; EARLY INTERVENTION; FEMALE; INTRACRANIAL PRESSURE; MICRODIALYSIS; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TRAUMATIC BRAIN INJURY; VASOCONSTRICTION;

ANIMALS; BRAIN; BRAIN INJURIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; FEMALE; MICRODIALYSIS; MONITORING, PHYSIOLOGIC; NEUROPROTECTIVE AGENTS; PHENYLEPHRINE; SWINE;

EID: 84864219421     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31825333e6     Document Type: Article

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