One-pot synthesis of poly(N-isopropylacrylamide)/chitosan composite microspheres via microemulsion

Carbohydrate Polymers

Volumn 90, Issue 1, 2012, Pages 690-695

  Gong, Yi ^a   Liu, Qing Lin ^a   Zhu, Ai Mei ^a   Zhang, Qiu Gen ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Chitosan; Drug delivery; Multisensitive microspheres; One pot synthesis; Poly(N isopropylacrylamide)

Indexed keywords

ACIDIC ENVIRONMENT; COMPOSITE MICROSPHERES; CROSS LINKED CHITOSAN; DRUG CARRIER; ENCAPSULATION EFFICIENCY; ISOPROPYLACRYLAMIDE; MULTI-RESPONSIVE; N-ISOPROPYLACRYLAMIDES; ONE-POT SYNTHESIS; PH RESPONSE; POTENTIAL APPLICATIONS; PREPARATION METHOD; TEMPERATURE-INDUCED; VOLUME PHASE TRANSITION;

ACRYLIC MONOMERS; ALKALINITY; CHITOSAN; DRUG DELIVERY; ENCAPSULATION; MICROEMULSIONS;

MICROSPHERES;

ACRYLIC ACID RESIN; CHITOSAN; EMULSION; MICROSPHERE; POLY-N-ISOPROPYLACRYLAMIDE;

EMULSION; MEDICINAL CHEMISTRY; METABOLISM; PROCEDURES; SYNTHESIS; X RAY DIFFRACTION;

ACRYLIC RESINS; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; EMULSIONS; MICROSPHERES; X-RAY DIFFRACTION;

EID: 84864153588     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2012.05.098     Document Type: Article

References (24)

1. B.L. Elodie Organic/inorganic nanocomposite colloids Encyclopedia of Nanoscience and Nanotechnology 8 1 2004 305 332
2. F. Chen, R.B. Shi, Y. Xue, L. Chen, and Q.H. Wan Templated synthesis of monodisperse mesoporous maghemite/silica microspheres for magnetic separation of genomic DNA Journal of Magnetism and Magnetic Materials 322 16 2010 2439 2445
3. C.Y. Chuang, T.M. Don, and W.Y. Chiu Preparation of environmental- responsive chitosan-based nanoparticles by self-assembly method Carbohydrate Polymers 84 2 2011 765 769
4. 2 nanoparticles Colloids and Surfaces A: Physicochemical and Engineering Aspects 318 1-3 2008 111 121
5. C. Duan, D. Zhang, F. Wang, D. Zheng, L. Jia, and F. Feng Chitosan-g-poly(N-isopropylacrylamide) based nanogels for tumor extracellular targeting International Journal of Pharmaceutics 409 1-2 2011 252 259
6. G. Fundueanu, M. Constantin, and P. Ascenzi Poly(vinyl alcohol) microspheres with pH- and thermosensitive properties as temperature-controlled drug delivery Acta Biomaterialia 6 10 2010 3899 3907
7. Y.Y. Gao, X.R. Chen, B. Liao, X.B. Ding, Z.H. Zheng, and X. Cheng Polyelectrolyte self-assembly approach to smart nanocontainers Polymer Bulletin 56 4-5 2006 305 311
8. A. Housni, and R. Narain Aqueous solution behavior of p(N-isopropyl acrylamide) in the presence of water-soluble macromolecular species European Polymer Journal 43 10 2007 4344 4354
9. G. Jiang, W. Qiu, and P.P. DeLuca Preparation and in vitro/in vivo evaluation of insulin-loaded poly(acryloyl-hydroxyethyl starch)-PLGA composite microspheres Pharmaceutical Research 20 3 2003 452 459
10. L.Y. Li, G.Y. Liu, D.B. Qin, and X.L. Yang Synthesis of P(EGDMA-co-MAA)/P(EGDMA-co-VPy)/titania/polymer tetra-layer microspheres Polymer Chemistry 1 5 2010 650 657
11. 4/poly(N-isopropylacrylamide)/chitosan composite microspheres with multiresponsive properties Industrial & Engineering Chemistry Research 47 20 2008 7700 7706
12. C.Y. Liu, J. Guo, W.L. Yang, J.H. Hu, C.C. Wang, and S.K. Fu Magnetic mesoporous silica microspheres with thermo-sensitive polymer shell for controlled drug release Journal of Materials Chemistry 19 27 2009 4764 4770
13. S. Medeiros, A. Santos, H. Fessi, and A. Elaissari Stimuli-responsive magnetic particles for biomedical applications International Journal of Pharmaceutics 403 1 2011 139 161
14. R.A.A. Muzzarelli Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone Carbohydrate Polymers 76 2 2009 167 182
15. R.A.A. Muzzarelli, J. Boudrant, D. Meyer, N. Manno, M. DeMarchis, and M.G. Paoletti Current views on fungal chitin/chitosan, human chitinases, food preservation, glucans, pectins and inulin: A tribute to Henri Braconnot, precursor of the carbohydrate polymers science, on the chitin bicentennial Carbohydrate Polymers 87 2 2012 995 1012
16. R.A.A. Muzzarelli, F. Greco, A. Busilacchi, V. Sollazzo, and A. Gigante Chitosan, hyaluronan and chondroitin sulfate in tissue engineering for cartilage regeneration: A review Carbohydrate Polymers 89 3 2012 723 739
17. R.H. Müller Colloidal carriers for controlled drug delivery and targeting: Modification, characterization and in vivo distribution 1991 CRC Press
18. K. Nagpal, S.K. Singh, and D.N. Mishra Chitosan nanoparticles: A promising system in novel drug delivery Chemical & Pharmaceutical Bulletin 58 11 2010 1423 1430
19. N. Sanoj Rejinold, P.R. Sreerekha, K.P. Chennazhi, S.V. Nair, and R. Jayakumar Biocompatible, biodegradable and thermo-sensitive chitosan-g-poly (N-isopropylacrylamide) nanocarrier for curcumin drug delivery International Journal of Biological Macromolecules 49 2 2011 161 172
20. R.M. Silva, G.A. Silva, O.P. Coutinho, J.F. Mano, and R.L. Reis Preparation and characterisation in simulated body conditions of glutaraldehyde crosslinked chitosan membranes Journal of Materials Science: Materials in Medicine 15 10 2004 1105 1112
21. V.R. Sinha, A.K. Singla, S. Wadhawan, R. Kaushik, R. Kumria, and K. Bansal Chitosan microspheres as a potential carrier for drugs International Journal of Pharmaceutics 274 1-2 2004 1 33
22. 2 composites for degradation of methyl orange European Polymer Journal 47 5 2011 1168 1175
23. W. Wei, L.Y. Wang, L. Yuan, Q. Wei, X.D. Yang, and Z.G. Su Preparation and application of novel microspheres possessing autofluorescent properties Advanced Functional Materials 17 16 2007 3153 3158
24. A.M. Zalfen, D. Nizet, C. Jerome, F. Frankenne, J.M. Foidart, and V. Maquet Controlled release of drugs from multi-component biomaterials Acta Biomaterialia 4 6 2008 1788 1796