Synthesis and characterization of a hypoxia-sensitive MRI probe

Chemistry - A European Journal

Volumn 18, Issue 31, 2012, Pages 9669-9676

  Rojas Quijano, Federico A ^a   Tircsõ, Gyula ^b   Tircsõné Benyõ, Enikó ^b   Baranyai, Zsolt ^b   Tran Hoang, Huan ^b   Kálmán, Ferenc K ^b   Gulaka, Praveen K ^c   Kodibagkar, Vikram D ^c   Aime, Silvio ^d   Kovács, Zoltán ^a   Sherry, A Dean ^a,e  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF TURIN   (Italy)

^e UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

imaging agents; imaging of hypoxic tissue; ligand design; relaxation properties; stability

Indexed keywords

AMIDE LINKAGES; BOUND WATERS; CARBOXYL GROUPS; GLIOMA CELLS; HYPOXIC CELLS; HYPOXIC TISSUES; IMAGING AGENT; IMAGING METHOD; IN-VITRO; IN-VIVO; ISCHEMIC HEART DISEASE; LIGAND DESIGN; MOLECULAR SIZE; MR IMAGING; NITROIMIDAZOLES; PATHOLOGIC CONDITIONS; PROTON NUCLEAR MAGNETIC RELAXATION DISPERSION; RELAXATION PROPERTY; RELAXIVITY; ROTATIONAL CORRELATION TIME; SIDE-CHAINS; TISSUE HYPOXIA; VARIABLE TEMPERATURE;

AMIDES; CONVERGENCE OF NUMERICAL METHODS; CYTOLOGY; DISEASES; GADOLINIUM; LIGANDS; MAGNETIC RESONANCE IMAGING; NITROGEN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTONS; RATS; TUMORS;

CELLS;

DIAGNOSTIC AGENT; GADOLINIUM; GADOLINIUM 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE; GADOTERIC ACID; HETEROCYCLIC COMPOUND; ORGANOMETALLIC COMPOUND;

ANIMAL; ANOXIA; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; MALE; METHODOLOGY; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; SYNTHESIS;

ANIMALS; ANOXIA; GADOLINIUM; HETEROCYCLIC COMPOUNDS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; RATS;

EID: 84864144412     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201200266     Document Type: Article

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