Global levels of H3K27me3 track with differentiation in Vivo and are deregulated by MYC in prostate cancer

American Journal of Pathology

Volumn 181, Issue 2, 2012, Pages 560-569

  Pellakuru, Laxmi G ^a   Iwata, Tsuyoshi ^a   Gurel, Bora ^a   Schultz, Denise ^a   Hicks, Jessica ^a   Bethel, Carlise ^a   Yegnasubramanian, Srinivasan ^a,b   De Marzo, Angelo M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; LYSINE; MYC PROTEIN; TRANSCRIPTION FACTOR EZH2;

ANIMAL TISSUE; ARTICLE; ATROPHY; CANCER CELL; CANCER STAGING; CELL DIFFERENTIATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; GENE OVEREXPRESSION; HISTONE METHYLATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROSTATE CARCINOMA; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN CONTENT; PROTEIN EXPRESSION; STEM CELL; TISSUE LEVEL;

ANIMALS; CELL COMPARTMENTATION; CELL DIFFERENTIATION; CELL LINE, TUMOR; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LYSINE; MALE; METHYLATION; MICE; ORGAN SPECIFICITY; POLYCOMB REPRESSIVE COMPLEX 2; PROSTATE; PROSTATECTOMY; PROSTATIC NEOPLASMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MYC; RNA, SMALL INTERFERING; STEM CELLS; TISSUE ARRAY ANALYSIS;

EID: 84864140283     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.04.021     Document Type: Article

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