Subcutaneous administration of polymerized type i collagen downregulates interleukin (IL)-17A, IL-22 and transforming growth factor-β1 expression, and increases Foxp3-expressing cells in localized scleroderma

Clinical and Experimental Dermatology

Volumn 37, Issue 6, 2012, Pages 599-609

  Furuzawa Carballeda, J ^a   Ortiz Avalos M ^b   Lima, G ^a   Jurado Santa Cruz, F ^b   Llorente, L ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b Dermatologic Centre Ladislao de la Pascua   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 4; METHYLPREDNISOLONE; POLYMERIZED COLLAGEN TYPE 1; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CLINICAL TRIAL; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; ECCHYMOSIS; FEMALE; FLOW CYTOMETRY; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INJECTION SITE PAIN; LOCALIZED SCLERODERMA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRURITUS; REGULATORY T LYMPHOCYTE; SKIN; SKIN ATROPHY; SKIN BIOPSY; SKIN FIBROSIS; T LYMPHOCYTE SUBPOPULATION; TREATMENT DURATION; UPREGULATION;

ADOLESCENT; ADULT; AGED; COLLAGEN TYPE II; DOUBLE-BLIND METHOD; DOWN-REGULATION; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-17; INTERLEUKINS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SCLERODERMA, LOCALIZED; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 84864129064     PISSN: 03076938     EISSN: 13652230     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2012.04385.x     Document Type: Article

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