Fetal exposure to high isoflurane concentration induces postnatal memory and learning deficits in rats

Biochemical Pharmacology

Volumn 84, Issue 4, 2012, Pages 558-563

  Kong, Fei Juan ^a   Ma, Lei Lei ^b   Hu, Wen Wen ^b   Wang, Wen Na ^b   Lu, Hui Shun ^b   Chen, Shu Ping ^a  

^a HANGZHOU FIRST PEOPLE'S HOSPITAL   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Fetal rats; Isoflurane; Memory and learning deficits; Neuron apoptosis; Synaptic plasticity

Indexed keywords

CASPASE 3; ISOFLURANE;

AMNESIA; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; FEMALE; FETUS; GESTATIONAL AGE; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEARNING DISORDER; MALE; MAZE TEST; NERVE CELL; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; SPATIAL MEMORY; SYNAPSE; TRANSMISSION ELECTRON MICROSCOPY;

ANESTHETICS, INHALATION; ANIMALS; CA1 REGION, HIPPOCAMPAL; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; ISOFLURANE; LEARNING; MATERNAL-FETAL EXCHANGE; MAZE LEARNING; MEMORY; NEURONS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS;

EID: 84864121983     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.06.001     Document Type: Article

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