메뉴 건너뛰기




Volumn 287, Issue 30, 2012, Pages 25640-25649

A venom-derived neurotoxin, Cstx-1, from the spider Cupiennius salei exhibits cytolytic activities

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; C TERMINUS; C-TERMINAL TAIL; CD MEASUREMENTS; CDNA LIBRARIES; CYTOLYTIC ACTIVITIES; EUKARYOTIC CELLS; HELICAL STRUCTURES; INSECT LARVAE; ION PERMEABILITY; MUSCLE CELL; NEW MECHANISMS; TRIFLUOROETHANOL; VENOM GLAND; XENOPUS OOCYTE;

EID: 84864106646     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.339051     Document Type: Article
Times cited : (36)

References (45)
  • 1
    • 58549091081 scopus 로고    scopus 로고
    • Fossil evidence for the origin of spider spinnerets, and a proposed arachnid order
    • Selden, P. A., Shear, W. A., and Sutton, M. D. (2008) Fossil evidence for the origin of spider spinnerets, and a proposed arachnid order. Proc. Natl. Acad. Sci. U.S.A. 105, 20781-20785
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 20781-20785
    • Selden, P.A.1    Shear, W.A.2    Sutton, M.D.3
  • 2
    • 80051742678 scopus 로고    scopus 로고
    • Version 11.5. online at research.amnh.org/entomology/spiders/catalog/ index.html.
    • Platnick, N. I. (2011) The World Spider Catalog, Version 11.5. online at research.amnh.org/entomology/spiders/catalog/index.html.
    • (2011) The World Spider Catalog
    • Platnick, N.I.1
  • 3
    • 80053531681 scopus 로고    scopus 로고
    • Venom composition and strategies in spiders. Is everything possible?
    • Kuhn-Nentwig, L., Stöcklin, R., and Nentwig, W. (2011) Venom composition and strategies in spiders. Is everything possible? Adv. Insect. Physiol. 40, 1-86
    • (2011) Adv. Insect. Physiol. , vol.40 , pp. 1-86
    • Kuhn-Nentwig, L.1    Stöcklin, R.2    Nentwig, W.3
  • 4
    • 0000833385 scopus 로고
    • Purification and characterization of an antibacterial peptide from venom of Lycosa singoriensis
    • Xu, K., Ji, Y., and Qu, X. (1989) Purification and characterization of an antibacterial peptide from venom of Lycosa singoriensis. Acta Zool. Sin. 35, 300-305
    • (1989) Acta Zool. Sin. , vol.35 , pp. 300-305
    • Xu, K.1    Ji, Y.2    Qu, X.3
  • 6
    • 76449103951 scopus 로고    scopus 로고
    • Transcriptome analysis of the venom glands of the Chinese wolf spider Lycosa singoriensis
    • Zhang, Y., Chen, J., Tang, X., Wang, F., Jiang, L., Xiong, X., Wang, M., Rong, M., Liu, Z., and Liang, S. (2010) Transcriptome analysis of the venom glands of the Chinese wolf spider Lycosa singoriensis. Zoology 113, 10-18
    • (2010) Zoology , vol.113 , pp. 10-18
    • Zhang, Y.1    Chen, J.2    Tang, X.3    Wang, F.4    Jiang, L.5    Xiong, X.6    Wang, M.7    Rong, M.8    Liu, Z.9    Liang, S.10
  • 7
    • 49649104531 scopus 로고    scopus 로고
    • Biochemical characterization of cysteine-rich peptides from Oxyopes sp. venom that block calcium ion channels
    • Villegas, E., Adachi-Akahane, S., Bosmans, F., Tytgat, J., Nakajima, T., and Corzo, G. (2008) Biochemical characterization of cysteine-rich peptides from Oxyopes sp. venom that block calcium ion channels. Toxicon 52, 228-236
    • (2008) Toxicon , vol.52 , pp. 228-236
    • Villegas, E.1    Adachi-Akahane, S.2    Bosmans, F.3    Tytgat, J.4    Nakajima, T.5    Corzo, G.6
  • 8
    • 0037189567 scopus 로고    scopus 로고
    • Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins
    • DOI 10.1074/jbc.M200511200
    • Corzo, G., Villegas, E., Gómez-Lagunas, F., Possani, L. D., Belokoneva, O. S., and Nakajima, T. (2002) Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins. J. Biol. Chem. 277, 23627-23637 (Pubitemid 34952200)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.26 , pp. 23627-23637
    • Corzo, G.1    Villegas, E.2    Gomez-Lagunas, F.3    Possani, L.D.4    Belokoneva, O.S.5    Nakajima, T.6
  • 10
    • 1942534998 scopus 로고    scopus 로고
    • Biochemistry, toxicology and ecology of the venom of the spider Cupiennius salei (Ctenidae)
    • DOI 10.1016/j.toxicon.2004.02.009, PII S0041010104000583
    • Kuhn-Nentwig, L., Schaller, J., and Nentwig, W. (2004) Biochemistry, toxicology and ecology of the venom of the spider Cupiennius salei (Ctenidae). Toxicon 43, 543-553 (Pubitemid 38520195)
    • (2004) Toxicon , vol.43 , Issue.5 , pp. 543-553
    • Kuhn-Nentwig, L.1    Schaller, J.2    Nentwig, W.3
  • 11
    • 77955656759 scopus 로고    scopus 로고
    • Howl, J., and Jones, S., eds. CRC Press, Taylor & Francis Group, Boca Raton, FL
    • Kuhn-Nentwig, L., Trachsel, C., Nentwig, W. (2009) in Bioactive Peptides (Howl, J., and Jones, S., eds.) pp. 447-464, CRC Press, Taylor & Francis Group, Boca Raton, FL
    • (2009) Bioactive Peptides , pp. 447-464
    • Kuhn-Nentwig, L.1    Trachsel, C.2    Nentwig, W.3
  • 13
    • 20744435937 scopus 로고    scopus 로고
    • Spider venom: Enhancement of venom efficacy mediated by different synergistic strategies in Cupiennius salei
    • DOI 10.1242/jeb.01594
    • Wullschleger, B., Nentwig, W., and Kuhn-Nentwig, L. (2005) Spider venom. Enhancement of venom efficacy mediated by different synergistic strategies in Cupiennius salei. J. Exp. Biol. 208, 2115-2121 (Pubitemid 40849981)
    • (2005) Journal of Experimental Biology , vol.208 , Issue.11 , pp. 2115-2121
    • Wullschleger, B.1    Nentwig, W.2    Kuhn-Nentwig, L.3
  • 15
    • 0028218809 scopus 로고
    • Purification of toxic peptides and the amino acid sequence of CSTX-1 from the multicomponent venom of Cupiennius salei (Araneae:Ctenidae)
    • DOI 10.1016/0041-0101(94)90082-5
    • Kuhn-Nentwig, L., Schaller, J., and Nentwig, W. (1994) Purification of toxic peptides and the amino acid sequence of CSTX-1 from the multicomponent venom of Cupiennius salei (Araneae:Ctenidae). Toxicon 32, 287-302 (Pubitemid 24104439)
    • (1994) Toxicon , vol.32 , Issue.3 , pp. 287-302
    • Kuhn-Nentwig, L.1    Schaller, J.2    Nentwig, W.3
  • 16
    • 34249809422 scopus 로고    scopus 로고
    • CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons
    • DOI 10.1016/j.neuropharm.2007.03.012, PII S0028390807000925
    • Kubista, H., Mafra, R. A., Chong, Y., Nicholson, G. M., Beirão, P. S., Cruz, J. S., Boehm, S., Nentwig, W., and Kuhn-Nentwig, L. (2007) CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons. Neuropharmacology 52, 1650-1662 (Pubitemid 46850752)
    • (2007) Neuropharmacology , vol.52 , Issue.8 , pp. 1650-1662
    • Kubista, H.1    Mafra, R.A.2    Chong, Y.3    Nicholson, G.M.4    Beirao, P.S.L.5    Cruz, J.S.6    Boehm, S.7    Nentwig, W.8    Kuhn-Nentwig, L.9
  • 17
    • 0034218788 scopus 로고    scopus 로고
    • A lysine rich C-terminal tail is directly involved in the toxicity of CSTX-1, a neurotoxic peptide from the venom of the spider Cupiennius salei
    • Kuhn-Nentwig, L., Schaller, J., Kämpfer, U., Imboden, H., Malli, H., and Nentwig, W. (2000) A lysine rich C-terminal tail is directly involved in the toxicity of CSTX-1, a neurotoxic peptide from the venom of the spider Cupiennius salei. Arch. Insect. Biochem. Physiol. 44, 101-111
    • (2000) Arch. Insect. Biochem. Physiol. , vol.44 , pp. 101-111
    • Kuhn-Nentwig, L.1    Schaller, J.2    Kämpfer, U.3    Imboden, H.4    Malli, H.5    Nentwig, W.6
  • 18
    • 0034672325 scopus 로고    scopus 로고
    • Estimation of protein secondary structure from circular dichroism spectra: Comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set
    • DOI 10.1006/abio.2000.4880
    • Sreerama, N., and Woody, R. W. (2000) Estimation of protein secondary structure from circular dichroism spectra. Comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Anal. Biochem. 287, 252-260 (Pubitemid 32006234)
    • (2000) Analytical Biochemistry , vol.287 , Issue.2 , pp. 252-260
    • Sreerama, N.1    Woody, R.W.2
  • 19
    • 3242877618 scopus 로고    scopus 로고
    • DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data
    • DOI 10.1093/nar/gkh371
    • Whitmore, L., and Wallace, B. A. (2004) DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data. Nucleic Acids Res. 32, W668-W673 (Pubitemid 38997420)
    • (2004) Nucleic Acids Research , vol.32 , Issue.WEB SERVER ISS.
    • Whitmore, L.1    Wallace, B.A.2
  • 20
    • 45849096536 scopus 로고    scopus 로고
    • Protein secondary structure analyses from circular dichroism spectroscopy. Methods and reference databases
    • Whitmore, L., and Wallace, B. A. (2008) Protein secondary structure analyses from circular dichroism spectroscopy. Methods and reference databases. Biopolymers 89, 392-400
    • (2008) Biopolymers , vol.89 , pp. 392-400
    • Whitmore, L.1    Wallace, B.A.2
  • 21
    • 78751582195 scopus 로고    scopus 로고
    • Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells
    • Kuhn-Nentwig, L., Willems, J., Seebeck, T., Shalaby, T., Kaiser, M., and Nentwig, W. (2011) Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells. Amino Acids 40, 69-76
    • (2011) Amino Acids , vol.40 , pp. 69-76
    • Kuhn-Nentwig, L.1    Willems, J.2    Seebeck, T.3    Shalaby, T.4    Kaiser, M.5    Nentwig, W.6
  • 24
    • 0023159107 scopus 로고
    • Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid
    • Sigel, E. (1987) Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid. J. Physiol. 386, 73-90
    • (1987) J. Physiol. , vol.386 , pp. 73-90
    • Sigel, E.1
  • 26
    • 33947311685 scopus 로고    scopus 로고
    • The universal algorithm of maturation for secretory and excretory protein precursors
    • DOI 10.1016/j.toxicon.2006.11.007, PII S0041010106004259
    • Kozlov, S. A., and Grishin, E. V. (2007) The universal algorithm of maturation for secretory and excretory protein precursors. Toxicon 49, 721-726 (Pubitemid 46441365)
    • (2007) Toxicon , vol.49 , Issue.5 , pp. 721-726
    • Kozlov, S.A.1    Grishin, E.V.2
  • 27
    • 0027418132 scopus 로고
    • Peptidylglycine α-amidating monooxygenase: A multifunctional protein with catalytic, processing, and routing domains
    • Eipper, B. A., Milgram, S. L., Husten, E. J., Yun, H. Y., and Mains, R. E. (1993) Peptidylglycine α-amidating monooxygenase. A multifunctional protein with catalytic, processing, and routing domains. Protein Sci. 2, 489-497 (Pubitemid 23119300)
    • (1993) Protein Science , vol.2 , Issue.4 , pp. 489-497
    • Eipper, B.A.1    Milgram, S.L.2    Husten, E.J.3    Yun, H.-Y.4    Mains, R.E.5
  • 29
    • 0025300073 scopus 로고
    • Peptide α-helicity in aqueous trifluoroethanol: Correlations with predicted α-helicity and the secondary structure of the corresponding regions of bovine growth hormone
    • DOI 10.1021/bi00475a025
    • Lehrman, S. R., Tuls, J. L., and Lund, M. (1990) Peptide α-helicity in aqueous trifluoroethanol. Correlations with predicted α-helicity and the secondary structure of the corresponding regions of bovine growth hormone. Biochemistry 29, 5590-5596 (Pubitemid 20202286)
    • (1990) Biochemistry , vol.29 , Issue.23 , pp. 5590-5596
    • Lehrman, S.R.1    Tuls, J.L.2    Lund, M.3
  • 30
    • 0029884694 scopus 로고    scopus 로고
    • GOR method for predicting protein secondary structure from amino acid sequence
    • Garnier, J., Gibrat, J. F., and Robson, B. (1996) GOR method for predicting protein secondary structure from amino acid sequence. Methods Enzymol. 266, 540-553
    • (1996) Methods Enzymol. , vol.266 , pp. 540-553
    • Garnier, J.1    Gibrat, J.F.2    Robson, B.3
  • 33
    • 62949143593 scopus 로고    scopus 로고
    • Concentration-dependent effect of GsMTx4 on mechanosensitive channels of small conductance in E. coli spheroplasts
    • Hurst, A. C., Gottlieb, P. A., and Martinac, B. (2009) Concentration-dependent effect of GsMTx4 on mechanosensitive channels of small conductance in E. coli spheroplasts. Eur. Biophys. J. 38, 415-425
    • (2009) Eur. Biophys. J. , vol.38 , pp. 415-425
    • Hurst, A.C.1    Gottlieb, P.A.2    Martinac, B.3
  • 34
    • 34250372979 scopus 로고    scopus 로고
    • Molecular dynamics simulations of a stretch-activated channel inhibitor GsMTx4 with lipid membranes: Two binding modes and effects of lipid structure
    • DOI 10.1529/biophysj.106.101071
    • Nishizawa, M., and Nishizawa, K. (2007) Molecular dynamics simulations of a stretch-activated channel inhibitor GsMTx4 with lipid membranes. Two binding modes and effects of lipid structure. Biophys. J. 92, 4233-4243 (Pubitemid 46910539)
    • (2007) Biophysical Journal , vol.92 , Issue.12 , pp. 4233-4243
    • Nishizawa, M.1    Nishizawa, K.2
  • 36
    • 51749085388 scopus 로고    scopus 로고
    • HELIQUEST.A web server to screen sequences with specific α-helical properties
    • Gautier, R., Douguet, D., Antonny, B., and Drin, G. (2008) HELIQUEST.A web server to screen sequences with specific α-helical properties. Bioinformatics 24, 2101-2102
    • (2008) Bioinformatics , vol.24 , pp. 2101-2102
    • Gautier, R.1    Douguet, D.2    Antonny, B.3    Drin, G.4
  • 37
    • 77953271751 scopus 로고    scopus 로고
    • A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain
    • Bohlen, C. J., Priel, A., Zhou, S., King, D., Siemens, J., and Julius, D. (2010) A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain. Cell 141, 834-845
    • (2010) Cell , vol.141 , pp. 834-845
    • Bohlen, C.J.1    Priel, A.2    Zhou, S.3    King, D.4    Siemens, J.5    Julius, D.6
  • 39
    • 3843082908 scopus 로고    scopus 로고
    • The scorpine family of defensins: Gene structure, alternative polyadenylation and fold recognition
    • Zhu, S., and Tytgat, J. (2004) The scorpine family of defensins. Gene structure, alternative polyadenylation, and -fold recognition. Cell. Mol. Life Sci. 61, 1751-1763 (Pubitemid 39044253)
    • (2004) Cellular and Molecular Life Sciences , vol.61 , Issue.14 , pp. 1751-1763
    • Zhu, S.1    Tytgat, J.2
  • 40
    • 0034646815 scopus 로고    scopus 로고
    • Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom
    • DOI 10.1016/S0014-5793(00)01384-3, PII S0014579300013843
    • Conde, R., Zamudio, F. Z., Rodríguez, M. H., and Possani, L. D. (2000) Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom. FEBS Lett. 471, 165-168 (Pubitemid 30190058)
    • (2000) FEBS Letters , vol.471 , Issue.2-3 , pp. 165-168
    • Conde, R.1    Zamudio, F.Z.2    Rodriguez, M.H.3    Possani, L.D.4
  • 42
    • 33845647560 scopus 로고    scopus 로고
    • Wide phylogenetic distribution of Scorpine and long-chain β-KTx-like peptides in scorpion venoms: Identification of "orphan" components
    • DOI 10.1016/j.peptides.2006.06.012, PII S0196978106004712, Invertebrate Neuropeptides VII
    • Diego-García, E., Schwartz, E. F., D'Suze, G., González, S. A., Batista, C. V., García, B. I., de la Vega, R. C., and Possani, L. D. (2007) Wide phylogenetic distribution of scorpine and long-chain β-KTx-like peptides in scorpion venoms. Identification of "orphan" components. Peptides 28, 31-37 (Pubitemid 44959184)
    • (2007) Peptides , vol.28 , Issue.1 , pp. 31-37
    • Diego-Garcia, E.1    Schwartz, E.F.2    D'Suze, G.3    Gonzalez, S.A.R.4    Batista, C.V.F.5    Garcia, B.I.6    De La, V.R.C.R.7    Possani, L.D.8
  • 45
    • 0037192798 scopus 로고    scopus 로고
    • Cupiennin 1, a new family of highly basic antimicrobial peptides in the venom of the spider Cupiennius salei (Ctenidae)
    • DOI 10.1074/jbc.M111099200
    • Kuhn-Nentwig, L., Müller, J., Schaller, J., Walz, A., Dathe, M., and Nentwig, W. (2002) Cupiennin 1, a new family of highly basic antimicrobial peptides in the venom of the spider Cupiennius salei (Ctenidae). J. Biol. Chem. 277, 11208-11216 (Pubitemid 34952883)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.13 , pp. 11208-11216
    • Kuhn-Nentwig, L.1    Muller, J.2    Schaller, J.3    Walz, A.4    Dathe, M.5    Nentwig, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.