TGFβ1 inhibits lymphatic endothelial cell differentiation from mouse embryonic stem cells

Journal of Cellular Physiology

Volumn 227, Issue 11, 2012, Pages 3593-3602

  Vittet, Daniel ^a,b,c   Merdzhanova, Galina ^a,b,c   Prandini, Marie Hélène ^a,b,c   Feige, Jean Jacques ^a,b,c   Bailly, Sabine ^a,b,c  

^a INSERM   (France)

^b CEA GRENOBLE   (France)

^c UNIV GRENOBLE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; TRANSCRIPTION FACTOR SOX18; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; COCULTURE; EMBRYO; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; LYMPHATIC SYSTEM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; COCULTURE TECHNIQUES; COUP TRANSCRIPTION FACTOR II; CULTURE MEDIA, SERUM-FREE; EMBRYONIC STEM CELLS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; MICE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SOXF TRANSCRIPTION FACTORS; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

MURINAE;

EID: 84864102624     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24063     Document Type: Article

References (28)

1. Avraham T, Daluvoy S, Zampell J, Yan A, Haviv YS, Rockson SG, Mehrara BJ. 2010. Blockade of transforming growth factor-beta1 accelerates lymphatic regeneration during wound repair. Am J Pathol 177: 3202-3214.
2. Berthier R, Prandini MH, Schweitzer A, Thevenon D, Martin-Sisteron H, Uzan G. 1997. The MS-5 murine stromal cell line and hematopoietic growth factors synergize to support the megakaryocytic differentiation of embryonic stem cells. Exp Hematol 25: 481-490.
3. Calonge MJ, Seoane J, Massague J. 2004. Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta. J Biol Chem 279: 23759-23765.
4. Clavin NW, Avraham T, Fernandez J, Daluvoy SV, Soares MA, Chaudhry A, Mehrara BJ. 2008. TGF-beta1 is a negative regulator of lymphatic regeneration during wound repair. Am J Physiol Heart Circ Physiol 295: H2113-H2127.
5. Francois M, Caprini A, Hosking B, Orsenigo F, Wilhelm D, Browne C, Paavonen K, Karnezis T, Shayan R, Downes M, Davidson T, Tutt D, Cheah KS, Stacker SA, Muscat GE, Achen MG, Dejana E, Koopman P. 2008. Sox18 induces development of the lymphatic vasculature in mice. Nature 456: 643-647.
6. Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, Reith AD, Laping NJ, Hill CS. 2002. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 62: 65-74.
7. Jakobsson L, Kreuger J, Claesson-Welsh L. 2007. Building blood vessels-stem cell models in vascular biology. J Cell Biol 177: 751-755.
8. Karpanen T, Alitalo K. 2008. Molecular biology and pathology of lymphangiogenesis. Annu Rev Pathol 3: 367-397.
9. Kattman SJ, Huber TL, Keller GM. 2006. Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell 11: 723-732.
10. Kiefer F, Adams RH. 2008. Lymphatic endothelial differentiation: Start out with Sox-carry on with Prox. Genome Biol 9: 243.
11. Kitajima K, Tanaka M, Zheng J, Sakai-Ogawa E, Nakano T. 2003. In vitro differentiation of mouse embryonic stem cells to hematopoietic cells on an OP9 stromal cell monolayer. Methods Enzymol 365: 72-783.
12. Kono T, Kubo H, Shimazu C, Ueda Y, Takahashi M, Yanagi K, Fujita N, Tsuruo T, Wada H, Yamashita JK. 2006. Differentiation of lymphatic endothelial cells from embryonic stem cells on OP9 stromal cells. Arterioscler Thromb Vasc Biol 26: 2070-2076.
13. Kreuger J, Nilsson I, Kerjaschki D, Petrova T, Alitalo K, Claesson-Welsh L. 2006. Early lymph vessel development from embryonic stem cells. Arterioscler Thromb Vasc Biol 26: 1073-1078.
14. Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T. 2009. M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 206: 1089-1102.
15. Liersch R, Nay F, Lu L, Detmar M. 2006. Induction of lymphatic endothelial cell differentiation in embryoid bodies. Blood 107: 1214-1216.
16. Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY. 2010. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest 120: 1694-1707.
17. Mallet C, Vittet D, Feige JJ, Bailly S. 2006. TGFbeta1 induces vasculogenesis and inhibits angiogenic sprouting in an embryonic stem cell differentiation model: Respective contribution of ALK1 and ALK5. Stem Cells 24: 2420-2427.
18. Nonaka H, Watabe T, Saito S, Miyazono K, Miyajima A. 2008. Development of stabilin2+ endothelial cells from mouse embryonic stem cells by inhibition of TGFbeta/activin signaling. Biochem Biophys Res Commun 375: 256-260.
19. Norrmen C, Tammela T, Petrova TV, Alitalo K. 2011. Biological basis of therapeutic lymphangiogenesis. Circulation 123: 1335-1351.
20. Oka M, Iwata C, Suzuki HI, Kiyono K, Morishita Y, Watabe T, Komuro A, Kano MR, Miyazono K. 2008. Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis. Blood 111: 4571-4579.
21. Prandini MH, Desroches-Castan A, Feraud O, Vittet D. 2007. No evidence for vasculogenesis regulation by angiostatin during mouse embryonic stem cell differentiation. J Cell Physiol 213: 27-35.
22. Risebro CA, Searles RG, Melville AA, Ehler E, Jina N, Shah S, Pallas J, Hubank M, Dillard M, Harvey NL, Schwartz RJ, Chien KR, Oliver G, Riley PR. 2009. Prox1 maintains muscle structure and growth in the developing heart. Development 136: 495-505.
23. Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G. 2010. The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev 24: 696-707.
24. Swiatek PJ, Gridley T. 1993. Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. Genes Dev 7: 2071-2084.
25. Tammela T, Alitalo K. 2010. Lymphangiogenesis: Molecular mechanisms and future promise. Cell 140: 460-476.
26. Vecchi A, Garlanda C, Lampugnani MG, Resnati M, Matteucci C, Stoppacciaro A, Schnurch H, Risau W, Ruco L, Mantovani A, Dejana E. 1994. Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium. Eur J Cell Biol 63: 247-254.
27. Vittet D, Prandini MH, Berthier R, Schweitzer A, Martin-Sisteron H, Uzan G, Dejana E. 1996. Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood 88: 3424-3431.
28. Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM. 2008. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature 453: 524-528.