Centrally administered apelin-13 induces depression-like behavior in mice

Brain Research Bulletin

Volumn 88, Issue 6, 2012, Pages 574-580

  Lv, Shuang Yu ^a   Qin, Yao Jun ^a   Wang, Hai Ting ^a   Xu, Ning ^a   Yang, Yan Jie ^a   Chen, Qiang ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Apelin 13; Depression; Forced swimming test; Opioid; Spontaneous activity

Indexed keywords

APELIN; APELIN 13; APELIN RECEPTOR; CORTICOTROPIN RELEASING FACTOR; KAPPA OPIATE RECEPTOR; NALOXONE; NORBINALTORPHIMINE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEPRESSION; EXPERIMENTAL TEST; FORCED SWIMMING TEST; IMMOBILIZATION; MALE; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; ROTAROD TEST; TAIL SUSPENSION TEST; WIRE HANGING TEST;

AMINO ACID SEQUENCE; ANIMALS; CORTICOTROPIN-RELEASING HORMONE; DEPRESSION; INJECTIONS; INJECTIONS, INTRAVENTRICULAR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MOTOR ACTIVITY; NALOXONE; NALTREXONE; PEPTIDE FRAGMENTS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, KAPPA; ROTAROD PERFORMANCE TEST; SINGLE-BLIND METHOD;

EID: 84864083981     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2012.06.003     Document Type: Article

References (58)

1. Arborelius L., Owens M.J., Plotsky P.M., Nemeroff C.B. The role of corticotropin-releasing factor in depression and anxiety disorders. Journal of Endocrinology 1999, 160:1-12.
2. Bals-Kubik R., Herz A., Shippenberg T.S. Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated. Psychopharmacology 1989, 98:203-206.
3. Befort K., Filliol D., Darcq E., Ghate A., Matifas A., Lardenois A., Muller J., Thibault C., Dembele D., Poch O., Kieffer B.L. Gene expression is altered in the lateral hypothalamus upon activation of the mu opioid receptor. Annals of the New York Academy of Sciences 2008, 1129:175-184.
4. Berrocoso E., Sanchez-Blazquez P., Garzon J., Mico J.A. Opiates as antidepressants. Current Pharmaceutical Design 2009, 15:1612-1622.
5. Bodkin J.A., Zornberg G.L., Lukas S.E., Cole J.O. Buprenorphine treatment of refractory depression. Journal of Clinical Psychopharmacology 1995, 15:49-57.
6. Borsini F., Meli A. Is the forced swimming test a suitable model for revealing an-tidepressant activity?. Psychopharmacology 1988, 94:147-161.
7. Boucher J., Masri B., Daviaud D., Gesta S., Guigné C., Mazzucotelli A., Castan-Laurell I., Tack I., Knibiehler B., Carpéné C., Audigier Y., Saulnier-Blache J.S., Valet P. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 2005, 146:1764-1771.
8. Carbajal D., Ravelo Y., Molina V., Mas R., Mde L. Arruzazabala D-004, a lipid extract from royal palm fruit, exhibits antidepressant effects in the forced swim test and the tail suspension test in mice. Pharmacology Biochemistry and Behavior 2009, 92:465-468.
9. Carlezon W.A., Béguin C., DiNieri J.A., Baumann M.H., Richards M.R., Todtenkopf M.S., Rothman R.B., Ma Z., Lee D.Y., Cohen B.M. Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats. Journal of Pharmacology and Experimental Therapeutics 2006, 316:440-447.
10. Cayabyab M., Hinuma S., Farzan M., Choe H., Fukusumi S., Kitada C., Nishizawa N., Hosoya M., Nishimura O., Messele T., Pollakis G., Goudsmit J., Fujino M., Sodroski J. Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry. Journal of Virology 2000, 74:11972-11976.
11. Christensen L. The effect of food intake on mood. Clinical Nutrition 2001, 20(Suppl. 1):161-166.
12. Darko D.F., Risch S.C., Gillin J.C., Golshan S. Association of beta-endorphin with specific clinical symptoms of depression. American Journal of Psychiatry 1992, 149:1162-1167.
13. Diamant M., de Wied D. Autonomic and behavioral effects of centrally administered corticotropin-releasing factor in rats. Endocrinology 1991, 129:446-454.
14. Falcão-Pires I., Goncalves N., Henriques-Coelho T., Moreira-Goncalves D., Roncon-Albuquerque R., Leite-Moreira A.F. Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension. American Journal of Physiology - Heart and Circulatory Physiology 2009, 296:H2007-H2014.
15. Ghadirian A.M., Gianoulakis C., Nair N.P. The effect of electroconvulsive therapy on endorphins in depression. Biological Psychiatry 1988, 23:459-464.
16. Haley T.J., McCormick W.G. Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse. British Journal of Pharmacology 1957, 12:12-15.
17. Holsboer F. The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety. Journal of Psychiatric Research 1999, 33:181-214.
18. Hosoya M., Kawamata Y., Fukusumi S., Fujii R., Habata Y., Hinuma S., Kitada C., Honda S., Kurokawa T., Onda H., Nishimura O., Fujino M. Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin. Journal of Biological Chemistry 2000, 275:21061-21067.
19. Jászberényi M., Bujdosó E., Telegdy G. Behavioral, neuroendocrine and thermoregulatory actions of apelin-13. Neuroscience 2004, 129:811-816.
20. Johnson S.A., Fournier N.M., Kalynchuk L.E. Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor. Behavioural Brain Research 2006, 168:280-288.
21. Kaster M.P., Budni J., Santos A.R., Rodrigues A.L. Pharmacological evidence for the involvement of the opioid system in the antidepressant-like effect of adenosine in the mouse forced swimming test. European Journal of Pharmacology 2007, 576:91-98.
22. 2A receptors. Neuroscience Letters 2004, 355:21-24.
23. Kawamata Y., Habata Y., Fukusumi S., Hosoya M., Fujii R., Hinuma S., Nishizawa N., Kitada C., Onda H., Nishimura O., Fujino M. Molecular properties of apelin: tissue distribution and receptor binding. Biochimica et Biophysica Acta 2001, 1538:162-171.
24. Kokare D.M., Dandekar M.P., Singru P.S., Gupta G.L., Subhedar N.K. Involvement of alpha-MSH in the social isolation induced anxiety- and depression-like behaviors in rat. Neuropharmacology 2010, 58:1009-1018.
25. Kuteeva E., Wardi T., Hökfelt T., Ogren S.O. Galanin enhances and a galanin antagonist attenuates depression-like behaviour in the rat. European Neuropsychopharmacology 2007, 17:64-69.
26. Lee D.K., Cheng R., Nguyen T., Fan T., Kariyawasam A.P., Liu Y., Osmond D.H., George S.R., O'Dowd B.F. Characterization of apelin, the ligand for the APJ receptor. Journal of Neurochemistry 2000, 74:34-41.
27. Lee D.K., Saldivia V.R., Nguyen T., Cheng R., George S.R., O'Dowd B.F. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action. Endocrinology 2005, 146:231-236.
28. Lee H.J., Tomioka M., Takaki Y., Masumoto H., Saido T.C. Molecular cloning and expression of aminopeptidase a isoforms from rat hippocampus. Biochimica et Biophysica Acta 2000, 1493:273-278.
29. Li Y., Chen J., Bai B., Du H., Liu Y., Liu H. Heterodimerization of human apelin and kappa opioid receptors: roles in signal transduction. Cellular Signalling 2012, 24:991-1001.
30. Licinio-Paixao J. Hyperinsulinemia; a mediator of decreased food intake and weight loss in anorexia nervosa and major depression. Medical Hypotheses 1989, 28:125-130.
31. Loewen N., Chen J., Dudley V.J., Sarthy V.P., Mathura J.R. Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network. Experimental Eye Research 2009, 88:928-937.
32. Lutter M., Sakata I., Osborne-Lawrence S., Rovinsky S.A., Anderson J.G., Jung S., Birnbaum S., Yanagisawa M., Elmquist J.K., Nestler E.J., Zigman J.M. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nature Neuroscience 2008, 11:752-753.
33. Lv S.Y., Yang Y.J., Qin Y.J., Mo J.R., Wang N.B., Wang Y.J., Chen Q. Central apelin-13 inhibits food intake via the CRF receptor in mice. Peptides 2012, 33:132-138.
34. Lv S.Y., Yang Y.J., Qin Y.J., Xiong W., Chen Q. Effect of centrally administered apelin-13 on gastric emptying and gastrointestinal transit in mice. Peptides 2011, 32:978-982.
35. Mansour A., Khachaturian H., Lewis M.E., Akil H., Waltson S.J. Anatomy of CNS opioid receptors. Trends in Neurosciences 1988, 11:308-314.
36. Masri B., Lahlou H., Mazarguil H., Knibiehler B., Audigier Y. Apelin (65-77) activates extracellular signal-regulated kinases via a PTX-sensitive G protein. Biochemical and Biophysical Research Communications 2002, 290:539-545.
37. Masri B., Morin N., Cornu M., Knibiehler B., Audigier Y. Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells. FASEB Journal 2004, 18:1909-1911.
38. Matussek N. Opioid system in depression. International Journal of Neuropsychopharmacology 2003, 6:443.
39. Mitra A., Katovich M.J., Mecca A., Rowland N.E. Effects of central and peripheral injections of apelin on fluid intake and cardiovascular parameters in rats. Physiology and Behavior 2006, 89:221-225.
40. Newson M.J., Roberts E.M., Pope G.R., Lolait S.J., O'Carroll A.M. The effects of apelin on hypothalamic-pituitary-adrenal axis neuroendocrine function are mediated through corticotrophin-releasing factor- and vasopressin-dependent mechanisms,. Journal of Endocrinology 2009, 202:123-129.
41. Niimi K., Takahashi E., Itakura C. Analysis of motor function and dopamine systems of SAMP6 mouse. Physiology and Behavior 2009, 96:464-469.
42. Porsolt R.D., Bertin A., Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Archives Internationales de Pharmacodynamie et de Therapie 1977, 229:327-336.
43. Reaux A., De Mota N., Skultetyova I., Lenkei Z., El Messari S., Gallatz K., Corvol P., Palkovits M., Llorens-Cortes C. Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain. Journal of Neurochemistry 2001, 77:1085-1096.
44. Reul J.M., Holsboer F. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Current Opinion in Pharmacology 2002, 2:23-33.
45. Saitoh A., Kimura Y., Suzuki T., Kawai K., Nagase H., Kamei J. Potential anxiolytic and antidepressant-like activities of SNC80, a selective delta-opioid agonist, in behavioral models in rodents. Journal of Pharmacological Sciences 2004, 95:374-380.
46. Steru L., Chermat R., Thierry B., Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 1985, 85:367-370.
47. Stogner K.A., Holmes P.V. Neuropeptide-Y exerts antidepressant-like effects in the forced swim test in rats. European Journal of Pharmacology 2000, 387:9-10.
48. Stoll A.L., Rueter S. Treatment augmentation with opiates in severe and refractory major depression. American Journal of Psychiatry 1999, 156:2017.
49. Sunter D., Hewson A.K., Dickson S.L. Intracerebroventricular injection of apelin-13 reduces food intake in the rat. Neuroscience Letters 2003, 353:1-4.
50. Taheri S., Murphy K., Cohen M., Sujkovic E., Kennedy A., Dhillo W., Dakin C., Sajedi A., Ghatei M., Bloom S. The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats. Biochemical and Biophysical Research Communications 2002, 291:1208-1212.
51. Tatemoto K., Hosoya M., Habata Y., Fujii R., Kakegawa T., Zou M.X., Kawamata Y., Fukusumi S., Hinuma S., Kitada C., Kurokawa T., Onda H., Fujino M. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochemical and Biophysical Research Communications 1998, 251:471-476.
52. Tatemoto K., Takayama K., Zou M.X., Kumaki I., Zhang W., Kumano K., Fujimiya M. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regulatory Peptides 2001, 99:87-92.
53. Wadenberg M.L. A review of the properties of spiradoline: a potent and selective κ-opioid receptor agonist. CNS Drug Reviews 2003, 9:187-198.
54. Xu N., Wang H., Fan L., Chen Q. Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice. Peptides 2009, 30:1153-1157.
55. Yang Y.J., Lv S.Y., Xiu M.H., Xu N., Chen Q. Intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice. Peptides 2010, 31:2241-2246.
56. Zeng X.J., Zhang L.K., Wang H.X., Lu L.Q., Ma L.Q., Tang C.S. Apelin protects heart against ischemia/reperfusion injury in rat. Peptides 2009, 30:1144-1152.
57. Zhou Y., Ren Y., Ma Z., Jia G., Gao X., Zhang L., Qin X. Identification and quantification of the major volatile constituents in antidepressant active fraction of xiaoyaosan by gas chromatography-mass spectrometry. Journal of Ethnopharmacology 2012, 141:187-192.
58. Zomkowski A.D., Santos A.R., Rodrigues A.L. Evidence for the involvement of the opioid system in the agmatine antidepressant-like effect in the forced swimming test. Neuroscience Letters 2005, 381:279-283.