Novel solvent-free gelucire extract of Plumbago zeylanica using non-everted rat intestinal sac method for improved therapeutic efficacy of plumbagin

Journal of Pharmacological and Toxicological Methods

Volumn 66, Issue 1, 2012, Pages 35-42

  Bothiraja, Chellampillai ^a   Pawar, Atmaram P ^b   Dama, Ganesh Y ^a   Joshi, Prajakta P ^a   Shaikh, Karimunnisa S ^c  

^a Sharadchandra Pawar College of Pharmacy   (India)

^b BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^c Affiliated to Savitribai Phule Pune University   (India)

Author keywords

Flux; Gelucire 44 14; In vivo study; Non everted rat intestinal sac model; Permeability coefficient; Plumbago zeylanica

Indexed keywords

ALCOHOL; CARBOXYMETHYLCELLULOSE; GELUCIRE; INDOMETACIN; PLUMBAGIN; PLUMBAGO ZEYLANICA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG ISOLATION; DRUG SOLUBILITY; DUODENUM; GASTROINTESTINAL TRACT; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HISTOPATHOLOGY; HYDROPHILICITY; ILEUM; INFLAMMATION; INTESTINE ABSORPTION; NONHUMAN; PAW EDEMA; PERMEABILITY; PLANT ROOT; RAT; THERMAL ANALYSIS; TOXICITY TESTING; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; CARRAGEENAN; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INFLAMMATION; INTESTINAL ABSORPTION; INTESTINES; LIQUID-LIQUID EXTRACTION; MALE; MICE; MODELS, BIOLOGICAL; NAPHTHOQUINONES; PERMEABILITY; PLANT EXTRACTS; PLUMBAGINACEAE; POLYETHYLENE GLYCOLS; RATS; TOXICITY TESTS, ACUTE; WATER;

PLUMBAGO ZEYLANICA; RATTUS;

EID: 84864078285     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2012.05.007     Document Type: Article

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