Proteomic Strategies to Investigate Adaptive Processes

Methods in Animal Proteomics

Volumn , Issue , 2011, Pages 189-209

  Epperson, L Elaine ^a   Martin, Sandra L ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

2D gels in combination, with fluorescent Cy dyes (DIGE; GE Healthcare) internal reference for normalization common to every gel; Hibernation physiology and behavior mammalian hibernation and circannual rhythm; Hibernation, like other adaptive phenotypes environmental cues for maintenance and transitions; Label and gel free proteomic approach investigating hibernation in liver of arctic ground squirrels; Living organisms, subject to changes in environment, challenges met by altering protein expression and enzymatic activities; Proper statistical analysis critical for arriving at accurate and meaningful results; Proteomics in animal biology investigating adaptive processes; Robust sampling strategy assessing changes in adaptive processes, critical phenotypic features in natural behavioral cycle; Two switch model of hibernation shifts in biomolecules, physiological and behavioral cycles of hibernation; Unique challenges, arising questions pertaining to behavioral adaptation of animals

Indexed keywords

EID: 84864067784     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470960660.ch8     Document Type: Chapter

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