A drug rape case involving triazolam detected in hair and urine

International Journal of Legal Medicine

Volumn 126, Issue 4, 2012, Pages 637-643

  Johansen, S Stybe ^a   Dahl Sorensen R ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Drug facilitated crime; Hair; Triazolam and metabolite hydroxytriazolam; Urine

Indexed keywords

ALPHA HYDROXYTRIAZOLAM; ALPHA-HYDROXYTRIAZOLAM; DRUG DERIVATIVE; HYPNOTIC SEDATIVE AGENT; TRIAZOLAM;

ADULT; ARTICLE; CASE REPORT; CHEMISTRY; FEMALE; HAIR; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RAPE; TANDEM MASS SPECTROMETRY; URINE;

ADULT; CHROMATOGRAPHY, LIQUID; FEMALE; HAIR; HUMANS; HYPNOTICS AND SEDATIVES; MASS SPECTROMETRY; RAPE; TANDEM MASS SPECTROMETRY; TRIAZOLAM;

EID: 84864059230     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-011-0654-6     Document Type: Article

References (15)

1. Kintz P (2007) Analytical and practical aspects ofdrug testing in hair. CRC Press, Taylor and Francis Group, Boca Raton, Florida, USA
2. Ropero-Miller JD (2007) A decade revisited - the forensic and clinical applications ofhairtesting. Forensic Sci Rev 19:49-67
3. Papadodima SA, Athanaselis SA, Spiliopoulou C (2007) Toxico-logical investigation of drug-facilitated sexual assaults. Int J Clin Pract 61:259-264
4. Chèze M, Duffort G, Deveaux M, Pépin G (2005) Hair analysis by liquid chromatography-tandem mass spectrometry in toxicological investigation ofdrug-facilitated crimes: Report of 128 cases over the period June 2003-May 2004 in metropolitan Paris. Forensic Sci Int 153:3-10 (Pubitemid 41008645)
5. Kintz P (2007) Bioanalytical procedures for detection of chemical agents in hair in the case of drug-facilitated crimes. Anal Bioanal Chem 388:1467-1474 (Pubitemid 47150873)
6. LeBeau MA, Mozayani A (2001) Drug-facilitated sexual assault: a forensic handbook. Academic Press, San Diego
7. Nielsen MKK, Johansen SS, Dalsgaard PW, Linnet K (2010) Simultaneous screening and quantification of 52 common pharma-ceuticals and drugs ofabuse in hair using UPLC-TOF-MS. Forensic Sci Int 196:85-92
8. Sun Q, Xiang P, Shen B, Yan H, Shen M (2010) Determination of triazolam and alpha-hydroxytriazolam in guinea pig hair after a single dose. J Anal Tox 34:89-94
9. Irving RC, Dickson SJ (2007) The detection of sedatives in hair and nail samples using tandem LC-MS-MS. Forensic Sci Int 166:58-67 (Pubitemid 46162012)
10. Chèze M, Muckensturm A, Hoizey G, Pépin G, Deveaux M (2010) A tendency for re-offending in drug-facilitated crime. Forensic Sci Int 196:14-17
11. Salomone A, Gerace E, Di Corcia D, Martra G, Petrarulo M, Vincenti M (2011) Hair analysis of drugs involved in drug-facilitated sexual assault and detection of zolpidem in a sus-pected case. Int J Legal Med, in press: DOI 10.1007/s00414-011-597-y
12. Toyo'oka T, Kanbori M, Kumaki Y, Nakahara Y (2001) Determi-nation of triazolam involving its hydroxy metabolites in hair shaft and hair root by reversed-phase liquid chromatography with elec-trospray ionization mass spectrometry and application to human hair analysis. Anal Biochem 295:172-179 (Pubitemid 32756971)
13. Xiang P, Qiran S, Shen B, Shen M (2011) Disposition ofketamine and norketamine in hair after a single dose. Int J Legal Med 125:831-840
14. Tsujikawa K, Kuwayama K, Miyaguchi H, Kanamori K, Iwata Y, Inoue H, Kishi T (2005) Urinary excretion profiles of two major triazolam metabolites, alpha-hydroxytriazolam and 4-hydroxytriazolam. J Anal Toxicol 29:240-243 (Pubitemid 40827570)
15. Pan RN, Hsiong CH, Huang PW, Tsai WS, Li WY, Pao LH (2011) Simultaneous quantification of triazolam and its metabolites in human urine by liquid chromatography-tandem mass spectrometry. J Anal Toxicol 35:170-175