메뉴 건너뛰기




Volumn 25, Issue 4, 2012, Pages 319-324

Dexamethasone down-regulates the inflammatory mediators but fails to reduce the tissue injury in the lung of acute pancreatitis rat models

Author keywords

Adhesion molecules; Chemokines; Glucocorticoids; Pulmonary damage

Indexed keywords

AMYLASE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; DEXAMETHASONE; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PADGEM PROTEIN;

EID: 84864038731     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2012.05.009     Document Type: Article
Times cited : (17)

References (37)
  • 1
    • 0026012825 scopus 로고
    • Evidence of intracellular activation of serine proteases in acute cerulein-induced pancreatitis in rats
    • Bialek R., Willemer S., Arnold R., Adler G. Evidence of intracellular activation of serine proteases in acute cerulein-induced pancreatitis in rats. Scand J Gastroenterol 1991, 26:190-196.
    • (1991) Scand J Gastroenterol , vol.26 , pp. 190-196
    • Bialek, R.1    Willemer, S.2    Arnold, R.3    Adler, G.4
  • 2
    • 0025979308 scopus 로고
    • Intracellular activation of digestive zymogens in rat pancreatic acini. Stimulation with high doses of cholecystokinin
    • Leach S.D., Modlin I.M., Scheele G.A., Gorelick F.S. Intracellular activation of digestive zymogens in rat pancreatic acini. Stimulation with high doses of cholecystokinin. J Clin Invest 1991, 87:362-366.
    • (1991) J Clin Invest , vol.87 , pp. 362-366
    • Leach, S.D.1    Modlin, I.M.2    Scheele, G.A.3    Gorelick, F.S.4
  • 3
    • 0031984853 scopus 로고    scopus 로고
    • The role of cytokines in the pathogenesis of acute pancreatitis
    • Norman J. The role of cytokines in the pathogenesis of acute pancreatitis. Am J Surg 1998, 175:76-83.
    • (1998) Am J Surg , vol.175 , pp. 76-83
    • Norman, J.1
  • 5
    • 0023724554 scopus 로고
    • Lung vascular permeability in patients with acute pancreatitis
    • Robertson C.S., Basran G.S., Hardy J.G. Lung vascular permeability in patients with acute pancreatitis. Pancreas 1988, 3:162-165.
    • (1988) Pancreas , vol.3 , pp. 162-165
    • Robertson, C.S.1    Basran, G.S.2    Hardy, J.G.3
  • 6
    • 0028231065 scopus 로고
    • Adhesion molecules and inflammatory injury
    • Albelda S.M., Smith C.W., Ward P.A. Adhesion molecules and inflammatory injury. FASEB J 1994, 8:504-512.
    • (1994) FASEB J , vol.8 , pp. 504-512
    • Albelda, S.M.1    Smith, C.W.2    Ward, P.A.3
  • 7
    • 1142299409 scopus 로고    scopus 로고
    • Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome
    • Bhatia M., Moochala S. Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. J Pathol 2004, 202:145-156.
    • (2004) J Pathol , vol.202 , pp. 145-156
    • Bhatia, M.1    Moochala, S.2
  • 8
    • 0024811721 scopus 로고
    • Neutrophil-dependent, oxygen-radical mediated lung injury associated with acute pancreatitis
    • Guice K.S., Oldham K.T., Caty M.G., Jonson K.J., Ward P.A. Neutrophil-dependent, oxygen-radical mediated lung injury associated with acute pancreatitis. Ann Surg 1989, 210:740-747.
    • (1989) Ann Surg , vol.210 , pp. 740-747
    • Guice, K.S.1    Oldham, K.T.2    Caty, M.G.3    Jonson, K.J.4    Ward, P.A.5
  • 10
    • 0023713254 scopus 로고
    • Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock
    • Luce J.M., Montgomery A.B., Marks J.D., Turner J., Metz C.A., Murray J.F. Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am Rev Respir Dis 1988, 138:62-68.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 62-68
    • Luce, J.M.1    Montgomery, A.B.2    Marks, J.D.3    Turner, J.4    Metz, C.A.5    Murray, J.F.6
  • 11
    • 0032496894 scopus 로고    scopus 로고
    • Effects of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome; a randomized controlled trial
    • Meduri G.U., Headley A.S., Goleen E., Carson S.J., Umberger R.A., Kelso T., et al. Effects of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome; a randomized controlled trial. J Am Med Assoc 1998, 280:159-165.
    • (1998) J Am Med Assoc , vol.280 , pp. 159-165
    • Meduri, G.U.1    Headley, A.S.2    Goleen, E.3    Carson, S.J.4    Umberger, R.A.5    Kelso, T.6
  • 12
    • 0032778048 scopus 로고    scopus 로고
    • Beneficial effects of hydrocortisone in a model of experimental acute pancreatitis
    • Osman M.O., Jacobsen N.O., Krestensen J.U., Larsen C.G., Jensen S.L. Beneficial effects of hydrocortisone in a model of experimental acute pancreatitis. Dig Surg 1999, 16:214-221.
    • (1999) Dig Surg , vol.16 , pp. 214-221
    • Osman, M.O.1    Jacobsen, N.O.2    Krestensen, J.U.3    Larsen, C.G.4    Jensen, S.L.5
  • 13
    • 3042737167 scopus 로고    scopus 로고
    • The role of glucocorticoid-dependent mechanism in the progression of sodium taurocholate-induced acute pancreatitis in the rat
    • Paszt A., Takács T., Rakonczay Z., Kaszaki J., Wolfard A., Tiszlavicz L., et al. The role of glucocorticoid-dependent mechanism in the progression of sodium taurocholate-induced acute pancreatitis in the rat. Pancreas 2004, 29:75-82.
    • (2004) Pancreas , vol.29 , pp. 75-82
    • Paszt, A.1    Takács, T.2    Rakonczay, Z.3    Kaszaki, J.4    Wolfard, A.5    Tiszlavicz, L.6
  • 14
    • 71849098246 scopus 로고    scopus 로고
    • Mechanisms of dexamethasone-mediated chemokine down-regulation in mild and severe acute pancreatitis
    • Yubero S., Ramudo L., Manso M.A., De Dios I. Mechanisms of dexamethasone-mediated chemokine down-regulation in mild and severe acute pancreatitis. Biochim Biophys Acta 2009, 1792:1205-1211.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 1205-1211
    • Yubero, S.1    Ramudo, L.2    Manso, M.A.3    De Dios, I.4
  • 15
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappaB by activated glucocorticoid receptors
    • Scheinman R.I., Gualberto A., Jewell C.M., Cidlowski J.A., Baldwin A.S. Characterization of mechanisms involved in transrepression of NF-kappaB by activated glucocorticoid receptors. Mol Cell Biol 1995, 15:943-953.
    • (1995) Mol Cell Biol , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin, A.S.5
  • 16
    • 0025188132 scopus 로고
    • Transcriptional interferente between c-Jun and the glucocortcoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction
    • Yang-Yen H.F., Chambord J.C., Sun Y.L., Smeal T., Schmidt T.J., Drovin J., et al. Transcriptional interferente between c-Jun and the glucocortcoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 1990, 62:1205-1215.
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.F.1    Chambord, J.C.2    Sun, Y.L.3    Smeal, T.4    Schmidt, T.J.5    Drovin, J.6
  • 17
    • 68149162963 scopus 로고    scopus 로고
    • Signal transduction of MCP-1 expression induced by pancreatitis-associated ascitic fluid in pancreatic cells
    • Ramudo L., Yubero S., Manso M.A., Vicente S., De Dios I. Signal transduction of MCP-1 expression induced by pancreatitis-associated ascitic fluid in pancreatic cells. J Cell Mol Med 2009, 7:1314-1320.
    • (2009) J Cell Mol Med , vol.7 , pp. 1314-1320
    • Ramudo, L.1    Yubero, S.2    Manso, M.A.3    Vicente, S.4    De Dios, I.5
  • 18
    • 36148941339 scopus 로고    scopus 로고
    • Beneficial effects of hydrocortisone in induced acute pancreatitis in rats
    • Sun W., Watanabe Y., Toki A., Wang Z. Beneficial effects of hydrocortisone in induced acute pancreatitis in rats. Chin Med J 2007, 120:1757-1761.
    • (2007) Chin Med J , vol.120 , pp. 1757-1761
    • Sun, W.1    Watanabe, Y.2    Toki, A.3    Wang, Z.4
  • 19
    • 34547929311 scopus 로고    scopus 로고
    • Study of the protective effects of dexamethasone on multiple organ injury in rats with severe acute pancreatitis
    • Zhang X.P., Zhang L., Wang Y., Cheng Q.H., Wang J.M., Cai W., et al. Study of the protective effects of dexamethasone on multiple organ injury in rats with severe acute pancreatitis. J Páncreas 2007, 8:400-412.
    • (2007) J Páncreas , vol.8 , pp. 400-412
    • Zhang, X.P.1    Zhang, L.2    Wang, Y.3    Cheng, Q.H.4    Wang, J.M.5    Cai, W.6
  • 21
    • 67349089319 scopus 로고    scopus 로고
    • Selective NF-κB inhibition, but not dexamethasone, decreases acute lung injury in a newborn piglet airway inflammation model
    • Von Bismarck P., Klemm K., Garcia-Wistdädt C.F., Winoto-Morbach S., Schütze S., Krause M.F. Selective NF-κB inhibition, but not dexamethasone, decreases acute lung injury in a newborn piglet airway inflammation model. Pulm Pharmacol Ther 2009, 22:297-304.
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 297-304
    • Von Bismarck, P.1    Klemm, K.2    Garcia-Wistdädt, C.F.3    Winoto-Morbach, S.4    Schütze, S.5    Krause, M.F.6
  • 22
    • 55949126332 scopus 로고    scopus 로고
    • Corticosteroid enhances TNFα-mediated leukocyte adhesion to pulmonary microvascular endotelial cells
    • Matsuda A., Orihara K., Fukuda S., Fujinaga H., Matsumoto K., Saito H. Corticosteroid enhances TNFα-mediated leukocyte adhesion to pulmonary microvascular endotelial cells. Allergy 2008, 63:1610-1616.
    • (2008) Allergy , vol.63 , pp. 1610-1616
    • Matsuda, A.1    Orihara, K.2    Fukuda, S.3    Fujinaga, H.4    Matsumoto, K.5    Saito, H.6
  • 23
    • 0242577362 scopus 로고    scopus 로고
    • N-acetylcysteine prevents intra-acinar oxygen free radical production in pancreatic duct obstruction-induced acute pancreatitis
    • Sevillano S., De la Mano A.M., Manso M.A., Orfao A., de Dios I. N-acetylcysteine prevents intra-acinar oxygen free radical production in pancreatic duct obstruction-induced acute pancreatitis. Biochim Biophys Acta 2003, 1639:177-184.
    • (2003) Biochim Biophys Acta , vol.1639 , pp. 177-184
    • Sevillano, S.1    De la Mano, A.M.2    Manso, M.A.3    Orfao, A.4    de Dios, I.5
  • 24
    • 0018876135 scopus 로고
    • Experimental pancreatitis in the rat. Ultrastructure of sodium taurocholate-induced pancreatic lesions
    • Aho H.J., Nevaleinen T.J. Experimental pancreatitis in the rat. Ultrastructure of sodium taurocholate-induced pancreatic lesions. Scand J Gastroenterol 1980, 15:417-424.
    • (1980) Scand J Gastroenterol , vol.15 , pp. 417-424
    • Aho, H.J.1    Nevaleinen, T.J.2
  • 25
    • 0014737490 scopus 로고
    • The secretion of pancreatic juice in response to stimulation of the vagus nerves in the pig
    • Hickson J.C. The secretion of pancreatic juice in response to stimulation of the vagus nerves in the pig. J Physiol 1970, 206:275-297.
    • (1970) J Physiol , vol.206 , pp. 275-297
    • Hickson, J.C.1
  • 26
    • 0033665578 scopus 로고    scopus 로고
    • Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury
    • Bhatia M., Brady M., Zagorski J., Christmas S.E., Campbell F., Neoptolemos J.P., et al. Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury. Gut 2000, 47:838-844.
    • (2000) Gut , vol.47 , pp. 838-844
    • Bhatia, M.1    Brady, M.2    Zagorski, J.3    Christmas, S.E.4    Campbell, F.5    Neoptolemos, J.P.6
  • 27
    • 0032464662 scopus 로고    scopus 로고
    • A rat model of acute respiratory distress syndrome (ARDS): part 1. Time dependency of histological and pathological changes
    • Germann P.G., Häfner D. A rat model of acute respiratory distress syndrome (ARDS): part 1. Time dependency of histological and pathological changes. J Pharmacol Toxicol Methods 1998, 40:101-107.
    • (1998) J Pharmacol Toxicol Methods , vol.40 , pp. 101-107
    • Germann, P.G.1    Häfner, D.2
  • 28
    • 0026970404 scopus 로고
    • Nuclear factor kappa B. An oxidative stress-responsive transcription factor of eukaryotic cells (a review)
    • Schreck T., Albermann K., Bauerle P.A. Nuclear factor kappa B. An oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radic Res Commun 1992, 17:221-223.
    • (1992) Free Radic Res Commun , vol.17 , pp. 221-223
    • Schreck, T.1    Albermann, K.2    Bauerle, P.A.3
  • 29
    • 0032416113 scopus 로고    scopus 로고
    • Activation of the JAK-STAT pathway by reactive oxygen species
    • Simon A.R., Rai U., Fanburg B.L., Cochran B.H. Activation of the JAK-STAT pathway by reactive oxygen species. Am J Physiol 1998, 275:C1640-C1652.
    • (1998) Am J Physiol , vol.275
    • Simon, A.R.1    Rai, U.2    Fanburg, B.L.3    Cochran, B.H.4
  • 30
    • 0033743875 scopus 로고    scopus 로고
    • Reactive oxygen species activate mitogen-activated protein kinases in pancreatic acinar cells
    • Dabrowski A., Boguslowicz C., Dabrowska M., Tribillo I., Gabryelewicz A. Reactive oxygen species activate mitogen-activated protein kinases in pancreatic acinar cells. Pancreas 2000, 21:376-384.
    • (2000) Pancreas , vol.21 , pp. 376-384
    • Dabrowski, A.1    Boguslowicz, C.2    Dabrowska, M.3    Tribillo, I.4    Gabryelewicz, A.5
  • 32
    • 59649120706 scopus 로고    scopus 로고
    • Targeting peripheral immune response reduces the severity of necrotizing acute pancreatitis
    • Yubero S., Ramudo L., Manso M.A., De Dios I. Targeting peripheral immune response reduces the severity of necrotizing acute pancreatitis. Crit Care Med 2009, 37:240-245.
    • (2009) Crit Care Med , vol.37 , pp. 240-245
    • Yubero, S.1    Ramudo, L.2    Manso, M.A.3    De Dios, I.4
  • 33
    • 63849135869 scopus 로고    scopus 로고
    • Effect of dexamethasone on acute respiratory distress syndrome induced by the H5N1 virus in mice
    • Xu T., Quiao J., Zhao L., He G., Li K., Wang J., et al. Effect of dexamethasone on acute respiratory distress syndrome induced by the H5N1 virus in mice. Eur Respir J 2009, 33:852-860.
    • (2009) Eur Respir J , vol.33 , pp. 852-860
    • Xu, T.1    Quiao, J.2    Zhao, L.3    He, G.4    Li, K.5    Wang, J.6
  • 34
    • 0025040966 scopus 로고
    • Evaluation of N-acetylcysteine and methylprednisolone as therapies for oxygen and acrolein-induced lung damage
    • Critchley J.A., Beeley J.M., Clark R.J., Summerfield M., Bell S., Spurlock M.S., et al. Evaluation of N-acetylcysteine and methylprednisolone as therapies for oxygen and acrolein-induced lung damage. Environ Health Perspect 1990, 85:89-94.
    • (1990) Environ Health Perspect , vol.85 , pp. 89-94
    • Critchley, J.A.1    Beeley, J.M.2    Clark, R.J.3    Summerfield, M.4    Bell, S.5    Spurlock, M.S.6
  • 35
    • 0031726450 scopus 로고    scopus 로고
    • Dexamethasone enhancement of hyperoxic lung inflammation in rats independent of adhesion molecule expression
    • Ramsay P.L., Smith C.V., Geske R.S., Montgomery C.A., Welty S.E. Dexamethasone enhancement of hyperoxic lung inflammation in rats independent of adhesion molecule expression. Biochem Pharmacol 1998, 56:259-268.
    • (1998) Biochem Pharmacol , vol.56 , pp. 259-268
    • Ramsay, P.L.1    Smith, C.V.2    Geske, R.S.3    Montgomery, C.A.4    Welty, S.E.5
  • 36
    • 0032717264 scopus 로고    scopus 로고
    • The role of polymorphonuclear leukocytes and oxygen-derived free radicals in experimental acute pancreatitis: mediators of local destruction and activators of local destruction and activators of inflammation
    • Poch B., Gansauge F., Rau B., Wittel U., Gansauge S., Nüssler A.K., et al. The role of polymorphonuclear leukocytes and oxygen-derived free radicals in experimental acute pancreatitis: mediators of local destruction and activators of local destruction and activators of inflammation. FEBS Lett 1999, 461:268-272.
    • (1999) FEBS Lett , vol.461 , pp. 268-272
    • Poch, B.1    Gansauge, F.2    Rau, B.3    Wittel, U.4    Gansauge, S.5    Nüssler, A.K.6
  • 37
    • 77949273899 scopus 로고    scopus 로고
    • Effect of dexamethasone on peripheral blood leukocyte immune response in bile-pancreatic duct obstruction-induced acute pancreatitis
    • Ramudo L., Yubero S., Manso M.A., Recio J.S., Werruaga E., De Dios I. Effect of dexamethasone on peripheral blood leukocyte immune response in bile-pancreatic duct obstruction-induced acute pancreatitis. Steroids 2010, 75:362-367.
    • (2010) Steroids , vol.75 , pp. 362-367
    • Ramudo, L.1    Yubero, S.2    Manso, M.A.3    Recio, J.S.4    Werruaga, E.5    De Dios, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.