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Volumn 7, Issue 7, 2012, Pages

Genipin inhibits mitochondrial uncoupling protein 2 expression and Ameliorates podocyte injury in diabetic mice

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; GENIPIN; GLUCOSE; MITOCHONDRIAL PROTEIN; PODOCIN; UNCOUPLING PROTEIN 2; WT1 PROTEIN;

EID: 84864034725     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041391     Document Type: Article
Times cited : (41)

References (41)
  • 1
    • 79955011399 scopus 로고    scopus 로고
    • Prevalence of diabetes and impaired fasting glucose in Chinese adults, China National Nutrition and Health Survey
    • Liu S, Wang W, Zhang J, He Y, Yao C, et al. (2002) Prevalence of diabetes and impaired fasting glucose in Chinese adults, China National Nutrition and Health Survey. Prev Chronic Dis 8: A13.
    • (2002) Prev Chronic Dis , vol.8
    • Liu, S.1    Wang, W.2    Zhang, J.3    He, Y.4    Yao, C.5
  • 2
    • 79551478706 scopus 로고    scopus 로고
    • High prevalence of diabetes and impaired fasting glucose among Chinese immigrants in New York City
    • Rajpathak SN, Wylie-Rosett J, (2011) High prevalence of diabetes and impaired fasting glucose among Chinese immigrants in New York City. J Immigr Minor Health 13: 181-183.
    • (2011) J Immigr Minor Health , vol.13 , pp. 181-183
    • Rajpathak, S.N.1    Wylie-Rosett, J.2
  • 3
    • 79951719256 scopus 로고    scopus 로고
    • Trends in the prevalence of type 2 diabetes in Asians versus whites: results from the United States National Health Interview Survey, 1997-2008
    • Lee JW, Brancati FL, Yeh HC, (2011) Trends in the prevalence of type 2 diabetes in Asians versus whites: results from the United States National Health Interview Survey, 1997-2008. Diabetes Care 34: 353-357.
    • (2011) Diabetes Care , vol.34 , pp. 353-357
    • Lee, J.W.1    Brancati, F.L.2    Yeh, H.C.3
  • 4
    • 78349286393 scopus 로고    scopus 로고
    • High prevalence of diabetic neuropathy in population-based patients diagnosed with type 2 diabetes in the Shanghai downtown
    • Lu B, Yang Z, Wang M, Yang Z, Gong W, et al. (2011) High prevalence of diabetic neuropathy in population-based patients diagnosed with type 2 diabetes in the Shanghai downtown. Diabetes Res Clin Pract 88: 289-294.
    • (2011) Diabetes Res Clin Pract , vol.88 , pp. 289-294
    • Lu, B.1    Yang, Z.2    Wang, M.3    Yang, Z.4    Gong, W.5
  • 5
    • 77950263954 scopus 로고    scopus 로고
    • Prevalence of diabetes among men and women in China
    • Yang W, Lu J, Weng J, Jia W, Ji L, et al. (2011) Prevalence of diabetes among men and women in China. N Engl J Med 362: 1090-1101.
    • (2011) N Engl J Med , vol.362 , pp. 1090-1101
    • Yang, W.1    Lu, J.2    Weng, J.3    Jia, W.4    Ji, L.5
  • 6
    • 78650647192 scopus 로고    scopus 로고
    • Renal biopsy in type 2 diabetes: timing of complications and evaluating of safety in Chinese patients
    • Zhang PP, Ge YC, Li SJ, Xie HL, Li LS, et al. (2011) Renal biopsy in type 2 diabetes: timing of complications and evaluating of safety in Chinese patients. Nephrology (Carlton) 16: 100-105.
    • (2011) Nephrology (Carlton) , vol.16 , pp. 100-105
    • Zhang, P.P.1    Ge, Y.C.2    Li, S.J.3    Xie, H.L.4    Li, L.S.5
  • 7
    • 0036433059 scopus 로고    scopus 로고
    • Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition
    • Langham RG, Kelly DJ, Cox AJ, Thomson NM, Holthofer H, et al. (2002) Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition. Diabetologia 45: 1572-1576.
    • (2002) Diabetologia , vol.45 , pp. 1572-1576
    • Langham, R.G.1    Kelly, D.J.2    Cox, A.J.3    Thomson, N.M.4    Holthofer, H.5
  • 8
    • 0036789206 scopus 로고    scopus 로고
    • Podocyte number in normotensive type 1 diabetic patients with albuminuria
    • White KE, Bilous RW, Marshall SM, El Nahas M, Remuzzi G, et al. (2002) Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes 51: 3083-3089.
    • (2002) Diabetes , vol.51 , pp. 3083-3089
    • White, K.E.1    Bilous, R.W.2    Marshall, S.M.3    El Nahas, M.4    Remuzzi, G.5
  • 9
    • 20044362239 scopus 로고    scopus 로고
    • From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy
    • Wolf G, Chen S, Ziyadeh FN, (2005) From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 54: 1626-1634.
    • (2005) Diabetes , vol.54 , pp. 1626-1634
    • Wolf, G.1    Chen, S.2    Ziyadeh, F.N.3
  • 10
    • 15844397902 scopus 로고    scopus 로고
    • Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice
    • Dai C, Yang J, Bastacky S, Xia J, Li Y, et al. (2004) Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice. J Am Soc Nephrol 15: 2637-2647.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2637-2647
    • Dai, C.1    Yang, J.2    Bastacky, S.3    Xia, J.4    Li, Y.5
  • 11
    • 79952767139 scopus 로고    scopus 로고
    • Role of angiotensin II in the development of nephropathy and podocytopathy of diabetes
    • Campbell KN, Raij L, Mundel P, (2011) Role of angiotensin II in the development of nephropathy and podocytopathy of diabetes. Curr Diabetes Rev 7: 3-7.
    • (2011) Curr Diabetes Rev , vol.7 , pp. 3-7
    • Campbell, K.N.1    Raij, L.2    Mundel, P.3
  • 13
    • 34547611903 scopus 로고    scopus 로고
    • Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy
    • Toyoda M, Najafian B, Kim Y, Caramori ML, Mauer M, (2007) Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy. Diabetes 56: 2155-2160.
    • (2007) Diabetes , vol.56 , pp. 2155-2160
    • Toyoda, M.1    Najafian, B.2    Kim, Y.3    Caramori, M.L.4    Mauer, M.5
  • 14
    • 33644783770 scopus 로고    scopus 로고
    • Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
    • Susztak K, Raff AC, Schiffer M, Bottinger EP, (2006) Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55: 225-233.
    • (2006) Diabetes , vol.55 , pp. 225-233
    • Susztak, K.1    Raff, A.C.2    Schiffer, M.3    Bottinger, E.P.4
  • 15
    • 69849089270 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria
    • Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, et al. (2009) Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol 20: 1997-2008.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1997-2008
    • Dai, C.1    Stolz, D.B.2    Kiss, L.P.3    Monga, S.P.4    Holzman, L.B.5
  • 16
    • 29144490392 scopus 로고    scopus 로고
    • Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene
    • Wharram BL, Goyal M, Wiggins JE, Sanden SK, Hussain S, et al. (2005) Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol 16: 2941-2952.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2941-2952
    • Wharram, B.L.1    Goyal, M.2    Wiggins, J.E.3    Sanden, S.K.4    Hussain, S.5
  • 17
    • 78650980097 scopus 로고    scopus 로고
    • Hypertension, dyslipidemia, and insulin resistance in patients with diabetes mellitus or the cardiometabolic syndrome: benefits of vasodilating beta-blockers
    • Deedwania P, (2011) Hypertension, dyslipidemia, and insulin resistance in patients with diabetes mellitus or the cardiometabolic syndrome: benefits of vasodilating beta-blockers. J Clin Hypertens (Greenwich) 13: 52-59.
    • (2011) J Clin Hypertens (Greenwich) , vol.13 , pp. 52-59
    • Deedwania, P.1
  • 18
    • 78651315324 scopus 로고    scopus 로고
    • Executive summary: standards of medical care in diabetes -2011
    • Executive summary: standards of medical care in diabetes -2011. Diabetes Care 34: S4-10.
    • Diabetes Care , vol.34
  • 19
    • 78650583734 scopus 로고    scopus 로고
    • Behavioral strategies in diabetes prevention programs: a systematic review of randomized controlled trials
    • Baker MK, Simpson K, Lloyd B, Bauman AE, Singh MA, (2011) Behavioral strategies in diabetes prevention programs: a systematic review of randomized controlled trials. Diabetes Res Clin Pract 91: 1-12.
    • (2011) Diabetes Res Clin Pract , vol.91 , pp. 1-12
    • Baker, M.K.1    Simpson, K.2    Lloyd, B.3    Bauman, A.E.4    Singh, M.A.5
  • 20
    • 79251613671 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus in 2010: individualizing treatment targets in diabetes care
    • Buse JB, (2011) Type 2 diabetes mellitus in 2010: individualizing treatment targets in diabetes care. Nat Rev Endocrinol 7: 67-68.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 67-68
    • Buse, J.B.1
  • 21
    • 77955875400 scopus 로고    scopus 로고
    • Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes
    • Deb DK, Sun T, Wong KE, Zhang Z, Ning G, et al. (2011) Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney Int 77: 1000-1009.
    • (2011) Kidney Int , vol.77 , pp. 1000-1009
    • Deb, D.K.1    Sun, T.2    Wong, K.E.3    Zhang, Z.4    Ning, G.5
  • 22
    • 79952197634 scopus 로고    scopus 로고
    • Treatment of db/db diabetic mice with triptolide: a novel therapy for diabetic nephropathy
    • Gao Q, Shen W, Qin W, Zheng C, Zhang M, et al. (2011) Treatment of db/db diabetic mice with triptolide: a novel therapy for diabetic nephropathy. Nephrol Dial Transplant 25: 3539-3547.
    • (2011) Nephrol Dial Transplant , vol.25 , pp. 3539-3547
    • Gao, Q.1    Shen, W.2    Qin, W.3    Zheng, C.4    Zhang, M.5
  • 23
    • 33748335467 scopus 로고    scopus 로고
    • Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms
    • Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, et al. (2006) Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms. Diabetes 55: 1666-1677.
    • (2006) Diabetes , vol.55 , pp. 1666-1677
    • Okada, T.1    Wada, J.2    Hida, K.3    Eguchi, J.4    Hashimoto, I.5
  • 24
    • 33744548069 scopus 로고    scopus 로고
    • Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets
    • Zhang CY, Parton LE, Ye CP, Krauss S, Shen R, et al. (2006) Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets. Cell Metab 3: 417-427.
    • (2006) Cell Metab , vol.3 , pp. 417-427
    • Zhang, C.Y.1    Parton, L.E.2    Ye, C.P.3    Krauss, S.4    Shen, R.5
  • 25
    • 0035875087 scopus 로고    scopus 로고
    • Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes
    • Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, et al. (2001) Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell 105: 745-755.
    • (2001) Cell , vol.105 , pp. 745-755
    • Zhang, C.Y.1    Baffy, G.2    Perret, P.3    Krauss, S.4    Peroni, O.5
  • 26
    • 48249127629 scopus 로고    scopus 로고
    • From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy
    • Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC 3rd (2008) From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 57: 1439-1445.
    • (2008) Diabetes , vol.57 , pp. 1439-1445
    • Qian, Y.1    Feldman, E.2    Pennathur, S.3    Kretzler, M.4    Brosius 3rd, F.C.5
  • 27
    • 20844432671 scopus 로고    scopus 로고
    • Pathogenetic mechanisms of diabetic nephropathy
    • Schena FP, Gesualdo L, (2005) Pathogenetic mechanisms of diabetic nephropathy. J Am Soc Nephrol 16: S30-33.
    • (2005) J Am Soc Nephrol , vol.16
    • Schena, F.P.1    Gesualdo, L.2
  • 28
    • 0037408389 scopus 로고    scopus 로고
    • Diabetic nephropathy in type 2 diabetes prevention and patient management
    • Wolf G, Ritz E, (2003) Diabetic nephropathy in type 2 diabetes prevention and patient management. J Am Soc Nephrol 14: 1396-1405.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1396-1405
    • Wolf, G.1    Ritz, E.2
  • 29
    • 0037407935 scopus 로고    scopus 로고
    • Overview: combating diabetic nephropathy
    • Ziyadeh FN, Sharma K, (2003) Overview: combating diabetic nephropathy. J Am Soc Nephrol 14: 1355-1357.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1355-1357
    • Ziyadeh, F.N.1    Sharma, K.2
  • 30
    • 0037408533 scopus 로고    scopus 로고
    • Overview of glucose signaling in mesangial cells in diabetic nephropathy
    • Haneda M, Koya D, Isono M, Kikkawa R, (2003) Overview of glucose signaling in mesangial cells in diabetic nephropathy. J Am Soc Nephrol 14: 1374-1382.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1374-1382
    • Haneda, M.1    Koya, D.2    Isono, M.3    Kikkawa, R.4
  • 31
    • 0037407520 scopus 로고    scopus 로고
    • Extracellular matrix metabolism in diabetic nephropathy
    • Mason RM, Wahab NA, (2003) Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol 14: 1358-1373.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1358-1373
    • Mason, R.M.1    Wahab, N.A.2
  • 32
    • 0037381607 scopus 로고    scopus 로고
    • Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes
    • Dalla Vestra M, Masiero A, Roiter AM, Saller A, Crepaldi G, et al. (2003) Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes. Diabetes 52: 1031-1035.
    • (2003) Diabetes , vol.52 , pp. 1031-1035
    • Dalla Vestra, M.1    Masiero, A.2    Roiter, A.M.3    Saller, A.4    Crepaldi, G.5
  • 33
    • 55749110018 scopus 로고    scopus 로고
    • Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy
    • Zheng S, Carlson EC, Yang L, Kralik PM, Huang Y, et al. (2008) Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy. J Am Soc Nephrol 19: 2077-2085.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2077-2085
    • Zheng, S.1    Carlson, E.C.2    Yang, L.3    Kralik, P.M.4    Huang, Y.5
  • 34
    • 34547628176 scopus 로고    scopus 로고
    • Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia
    • Davis B, Dei Cas A, Long DA, White KE, Hayward A, et al. (2007) Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia. J Am Soc Nephrol 18: 2320-2329.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2320-2329
    • Davis, B.1    Dei Cas, A.2    Long, D.A.3    White, K.E.4    Hayward, A.5
  • 35
    • 33645456580 scopus 로고    scopus 로고
    • Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival
    • Eremina V, Cui S, Gerber H, Ferrara N, Haigh J, et al. (2006) Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol 17: 724-735.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 724-735
    • Eremina, V.1    Cui, S.2    Gerber, H.3    Ferrara, N.4    Haigh, J.5
  • 36
    • 79957881425 scopus 로고    scopus 로고
    • Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
    • Godel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, et al. (2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 121: 2197-2209.
    • (2011) J Clin Invest , vol.121 , pp. 2197-2209
    • Godel, M.1    Hartleben, B.2    Herbach, N.3    Liu, S.4    Zschiedrich, S.5
  • 37
    • 33746491157 scopus 로고    scopus 로고
    • Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling
    • Dai C, Stolz DB, Bastacky SI, St-Arnaud R, Wu C, et al. (2006) Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling. J Am Soc Nephrol 17: 2164-2175.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2164-2175
    • Dai, C.1    Stolz, D.B.2    Bastacky, S.I.3    St-Arnaud, R.4    Wu, C.5
  • 38
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J, Liu Y, (2001) Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 159: 1465-1475.
    • (2001) Am J Pathol , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 39
    • 80053377598 scopus 로고    scopus 로고
    • Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glomerular podocytes
    • Bu X, Zhou Y, Zhang H, Qiu W, Chen L, et al. (2011) Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glomerular podocytes. Am J Physiol Renal Physiol 301: F784-792.
    • (2011) Am J Physiol Renal Physiol , vol.301
    • Bu, X.1    Zhou, Y.2    Zhang, H.3    Qiu, W.4    Chen, L.5
  • 40
    • 39549098861 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria
    • Li Y, Kang YS, Dai C, Kiss LP, Wen X, et al. (2008) Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol 172: 299-308.
    • (2008) Am J Pathol , vol.172 , pp. 299-308
    • Li, Y.1    Kang, Y.S.2    Dai, C.3    Kiss, L.P.4    Wen, X.5
  • 41
    • 22344443467 scopus 로고    scopus 로고
    • WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment
    • Rico M, Mukherjee A, Konieczkowski M, Bruggeman LA, Miller RT, et al. (2005) WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment. Am J Physiol Renal Physiol 289: F431-441.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Rico, M.1    Mukherjee, A.2    Konieczkowski, M.3    Bruggeman, L.A.4    Miller, R.T.5


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