A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation

Genes and Development

Volumn 26, Issue 14, 2012, Pages 1587-1601

  Huang, Hui ^a   Woo, Andrew J ^a   Waldon, Zachary ^a   Schindler, Yocheved ^a   Moran, Tyler B ^a   Zhu, Helen H ^b   Feng, Gen Sheng ^b   Steen, Hanno ^a   Cantor, Alan B ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

C Src; Megakaryocyte; RUNX1; Shp2; T cell; Tyrosine phosphorylation

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE SHP 2; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR RUNX1;

ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; DNA BINDING; GENETIC TRANSDUCTION; HEMATOPOIESIS; INHIBITION KINETICS; LYMPHOCYTE DIFFERENTIATION; MEGAKARYOCYTE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; RETROVIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE; CHROMOSOMAL PROTEINS, NON-HISTONE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; GATA1 TRANSCRIPTION FACTOR; HEMATOPOIESIS; HUMANS; MEGAKARYOCYTES; MICE; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSCRIPTION FACTORS;

EID: 84864019022     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.192054.112     Document Type: Article

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